2 results match your criteria: "and Pathology. Complutense University of Madrid[Affiliation]"

Impact of probiotic treatment on clinical symptom reduction in schizophrenia: A systematic review and meta-analysis.

J Psychiatr Res

January 2025

Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain; CIBERSAM-ISCIII (Biomedical Research Networking Centre for Mental Health/Carlos III Health Institute), Spain; Department of Legal Medicine, Psychiatry, and Pathology. Complutense University of Madrid, Madrid, Spain. Electronic address:

Introduction: Recent research has identified gut microbiota dysbiosis as a potential contributing factor in schizophrenia, leading to growing interest in exploring probiotics as a complementary approach to traditional antipsychotic treatments. This study aims to systematically evaluate the current evidence on the efficacy of probiotics in improving clinical symptoms of schizophrenia, offering a novel perspective into their potential role as an adjunctive strategy.

Methods: A systematic search was conducted to review randomized clinical trials, adhering to the PRISMA guidelines.

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Social dysfunction relates to shifts within socioaffective brain systems among Schizophrenia and Alzheimer's disease patients.

Eur Neuropsychopharmacol

September 2024

Amsterdam UMC, location Vrije Universiteit Amsterdam, Department of Psychiatry, Boelelaan 1117, Amsterdam, the Netherlands; Institute of Education & Child Studies, Section Forensic Family & Youth Care, Leiden University, the Netherlands.

Article Synopsis
  • Social dysfunction is a common feature of neuropsychiatric disorders like Schizophrenia and Alzheimer's disease, impacting socioaffective neural processing.
  • A study analyzed how social dysfunction correlates with brain system activity in SZ and AD patients through fMRI tasks, revealing patterns related to emotional responses.
  • The research found that severe behavioral social dysfunction linked to hyperactivity and hypoactivity in specific brain regions, highlighting the potential for tailored care based on individual social behavior.
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