6 results match your criteria: "and Neuromed Institute IRCCS[Affiliation]"
Neurol Sci
January 2019
Department of Neurology and Psychiatry, Sapienza University of Rome, and Neuromed Institute IRCCS, Pozzilli, Italy.
Background: Diagnosis of focal dystonia is based on clinical grounds and is therefore open to bias. To date, diagnostic guidelines have been only proposed for blepharospasm and laryngeal dystonia. To provide practical guidance for clinicians with less expertise in dystonia, a group of Italian Movement Disorder experts formulated clinical diagnostic recommendations for cervical, oromandibular, and limb dystonia.
View Article and Find Full Text PDFExpert Rev Neurother
February 2017
a Department of Neurology and Psychiatry , Sapienza University of Rome and Neuromed Institute IRCCS, Pozzilli , Italy.
This review will first discuss evidence of motor and sensory abnormalities as yielded by neurophysiological techniques in patients with PD. It will then go on to describe the effects of L-dopa replacement on motor and sensory abnormalities in PD as assessed by neurophysiological studies. Areas covered: We analyzed papers in English using Pubmed with the following keywords: L-dopa, dopamine, bradykinesia, basal ganglia, kinematic analysis, TMS, motor cortex plasticity, motor cortex excitability, somatosensory discrimination threshold, pain Expert commentary: L-dopa improves the amplitude and speed of upper limb voluntary movements, but it does not restore abnormalities in the sequence effect or voluntary facial movements.
View Article and Find Full Text PDFJ Neurol
June 2008
Department of Neurological Sciences and Neuromed Institute (IRCCS), University of Rome "La Sapienza", Viale dell'Università, 30, 00185 Roma, Italy.
Objective: To investigate possible changes in autonomic cardiovascular regulation and cardiopulmonary baroreflex sensitivity in patients with primary cervical dystonia receiving chronic treatment with botulinum toxin type A.
Methods: Short-term power spectral analysis of heart rate and systolic blood pressure variability, high-frequency and low-frequency oscillations of heart rate variability, low frequency/high frequency ratio and baroreflex sensitivity (alpha index) were measured in 12 patients with cervical dystonia before and 2-4 weeks after botulinum toxin type A injection and compared with normative data.
Results: Before treatment, at rest, patients had significantly lower high frequency power than healthy subjects (p < 0.
Eur J Neurol
February 2008
Department of Neurological Sciences and Neuromed Institute (IRCCS), 'La Sapienza' University of Rome, Rome, Italy.
Diffusion tensor imaging (DTI) analyses the movement of water molecules within the cerebral white matter thus providing information on ultrastructural brain changes. We studied 18 patients with cervical dystonia (CD), 16 with blepharospasm (BSP) and 35 years age-matched healthy controls. DTI data were obtained with a Philips 1.
View Article and Find Full Text PDFMov Disord
January 2008
Department of Neurological Sciences and Neuromed Institute (IRCCS), La Sapienza University of Rome, Rome, Italy.
Mirror movements (MM) refer to ipsilateral involuntary movements that appear during voluntary activity in contralateral homologous body regions. This study aimed to compare the frequency and distribution of MM in an unselected sample of 274 patients with Parkinson's disease (PD) and 100 healthy subjects, and to check a possible relationship between MM and parkinsonian features. MM of the hand were scored according to the Woods and Teuber scale.
View Article and Find Full Text PDFMov Disord
July 2007
Department of Neurological Sciences and Neuromed Institute (IRCCS), University of Rome "La Sapienza", Rome, Italy.
Repetitive transcranial magnetic stimulation (rTMS) delivered at 5 Hz frequency and suprathreshold (RMT) intensity produces a progressive facilitation of motor-evoked potential (MEP) amplitude that outlasts the end of stimulation. This phenomenon is related to a short-term enhancement of cortical excitatory interneurones. In this study, we investigated whether 5 Hz-rTMS elicits similar MEP facilitation during stimulation and similar facilitatory after-effects in patients with upper limb dystonia and healthy subjects.
View Article and Find Full Text PDF