3 results match your criteria: "and National Institutes for Food and Drug Control[Affiliation]"
Competitive adsorption on gold nanoparticles for human papillomavirus 16 L1 protein detection by LDI-MS.
Analyst
November 2019
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
The detection of the HPV L1 protein provides information about the infection status of the virus, reflects the replication status of the HPV virus in cervical cells, and helps understand the regression and progress of cervical lesions. Herein, we report a novel laser desorption ionization mass spectrometry (LDI MS) method for the sensitive detection of the HPV 16 L1 protein, based on non-covalent competitive adsorption between the HPV 16 L1 aptamer and melamine on gold nanoparticles (AuNPs). The intensity of the MS signal corresponding to the mass tag shows a linear relationship with the HPV 16 L1 concentration in the range 2-80 ng mL, with a limit of detection (LOD) of 58.
View Article and Find Full Text PDFHepatitis C Virus Subtype and Evolution Characteristic Among Drug Users, Men Who Have Sex With Men, and the General Population in Beijing, China.
Medicine (Baltimore)
February 2016
From the State Key Laboratory of Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention (China CDC) (YJ, YS, LM), Beijing Chaoyang District Center for Disease Control and Prevention, Beijing, China (YJ, XZ, CW, LL, JL, YH, PH, ZZ, SJ, SL); Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (KJB, DM); Institute of Pathogen Biology and AIDS Research Center, Chinese Academy of Medical Sciences and Peking Union Medical College (HW); and National Institutes for Food and Drug Control, Beijing, China (JD).
The aim of this study was to characterize the current molecular epidemiology of hepatitis C virus (HCV) infection and evaluate the evolutionary patterns of HCV subtypes in Beijing, China, among different subpopulations.The whole blood samples and behavioral data were collected from a total of 10,354 subjects, including drug users (DUs), men who have sex with men (MSM), and the general population, in Beijing from 2010 to 2011. Samples were tested for HCV infection using both enzyme-linked immunosorbent assay (ELISA) and real-time PCR.
View Article and Find Full Text PDFAn inactivated enterovirus 71 vaccine in healthy children.
N Engl J Med
February 2014
From Guangxi Province Center for Disease Control and Prevention, Nanning (R.L., Z.M., Y. Li, T.H., Y.N.), Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming (L.L., Y.Z., Jingjing Wang, L.J., C.D., Y.C., Z.X., L.W., Y. Liao, Y. Liang, J.L., H.Z., R.N., L.G., J.P., E.Y., L.S., P.C., H.S., Q.L.), Key Laboratory Medical Molecular Virology, Ministries of Education and Health, and the Institutes of Biomedical Science, Shanghai Medical College, Fudan University, Shanghai (X.W.), Department of Health Statistics, Fourth Military Medical University, Xi'an (J.X., Z.J.), and National Institutes for Food and Drug Control, Beijing (Z.L., Q.M., Junzhi Wang) - all in China.
Background: Enterovirus 71 (EV71) is a major cause of hand, foot, and mouth disease in children and may be fatal. A vaccine against EV71 is needed.
Methods: We conducted a randomized, double-blind, placebo-controlled phase 3 trial involving healthy children 6 to 71 months of age in Guangxi Zhuang Autonomous Region, China.