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Cerebral perfusion pressure thresholds for brain tissue hypoxia and metabolic crisis after poor-grade subarachnoid hemorrhage.
Stroke
May 2011
Neurological Intensive Care Unit, Department of Neurology, Columbia University Medical Center, and Milstein Hospital, 177 Fort Washington, 8-300, New York, NY 10032, USA.
Background And Purpose: To identify a minimally acceptable cerebral perfusion pressure threshold above which the risks of brain tissue hypoxia (BTH) and oxidative metabolic crisis are reduced for patients with subarachnoid hemorrhage (SAH).
Methods: We studied 30 poor-grade SAH patients who underwent brain multimodality monitoring (3042 hours). Physiological measures were averaged over 60 minutes for each collected microdialysis sample.