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New concepts in molecular imaging: non-invasive MRI spotting of proteolysis using an Overhauser effect switch.
PLoS One
June 2009
INSERM IFR 004, and Magnetic Resonance Center CNRS UMR 5536 University Victor Segalen Bordeaux, Bordeaux, France.
Background: Proteolysis, involved in many processes in living organisms, is tightly regulated in space and time under physiological conditions. However deregulation can occur with local persistent proteolytic activities, e.g.
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