2 results match your criteria: "and Lyon Neuroscience Research Center (CRNL)[Affiliation]"
Opsoclonus-Ataxia Syndrome in a Patient With Small-Cell Lung Cancer Treated With Immune Checkpoint Inhibitors.
Neurol Neuroimmunol Neuroinflamm
September 2024
From the French Reference Centre on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (A. Farina, M.V.-G., M.B., J.H., B.J.), Hospices Civils de Lyon, Hôpital Neurologique, Bron; MeLiS-UCBL-CNRS UMR 5284. INSERM U1314, Université Claude Bernard Lyon 1; Department of Neurology (F.L.), University Hospital of La Réunion, Saint-Pierre; and Lyon Neuroscience Research Center (CRNL) (A. Fourier), Université de Lyon, CNRS, INSERM, France.
Objectives: To describe a case of post-immune checkpoint inhibitor (ICI) opsoclonus-myoclonus-ataxia syndrome (OMAS), with complete clinical remission after treatment.
Methods: A 52-year-old man was admitted because of subacute-onset vertigo, dysarthria, vomiting, and weight loss. He was under atezolizumab (anti-PD-L1) monotherapy (23 cycles) for metastatic small-cell lung cancer, with excellent response.
Central Nervous System Underpinnings of Sensory Hypersensitivity in Migraine: Insights from Neuroimaging and Electrophysiological Studies.
Headache
October 2016
Neurological Hospital Pierre Wertheimer: Functional Neurology and Epilepsy Department, Hospices Civils de Lyon and Claude Bernard Lyon1 University, Lyon, France, and Lyon Neuroscience Research Center (CRNL), Neuropain team, INSERM U1028, CNRS UMR5292, Lyon, France.
Whereas considerable data have been generated about the pathophysiology of pain processing during migraine attacks, relatively little is known about the neural basis of sensory hypersensitivity. In migraine, the term "hypersensitivity" encompasses different and probably distinct pathophysiological aspects of sensory sensitivity. During attacks, many patients have enhanced sensitivity to visual, auditory and/or olfactory stimuli, which can enhance headache while interictally, migraineurs often report abnormal sensitivity to environmental stimuli that can cause nonpainful discomfort.
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