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Hypoglycemia attributable to insulin-like growth factor-II prohormone-producing metastatic leiomyosarcoma.

Endocr Pract

April 2005

Department of Medicine, Physiology, and Biophysics, University of South Florida for Health Sciences, and J. A. Haley Veterans Hospital, Tampa, Florida, USA.

Objective: To review the causes of nonpancreatic tumor-associated hypoglycemia and report the first case of hypoglycemia attributable to a leiomyosarcoma, which did not cause hypoglycemia in its primary site but only after metastasizing.

Methods: A case report is presented of a 62-year-old man with a gastric leiomyosarcoma diagnosed and surgically treated 8 years previously, who was found to have 14 large, rounded masses in his liver and a blood glucose level of 19 mg/dL. Biopsy of the largest mass revealed a leiomyosarcoma.

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