8 results match your criteria: "and Hunan Medical Center for Mental Health[Affiliation]"

Background: Critical care nurses are vulnerable to depression, which not only lead to poor well-being and increased turnover intention, but also affect their working performances and organizational productivity as well. Work related factors are important drivers of depressive symptoms. However, the non-liner and multi-directional relationships between job demands-resources and depressive symptoms in critical care nurses has not been adequately analyzed.

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Impairment of olfactory identification ability in ultra-high risk for psychosis and drug-naïve first episode psychosis.

Prog Neuropsychopharmacol Biol Psychiatry

July 2024

Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China; China National Technology Institute on Mental Disorders, Hunan Key Laboratory of Psychiatry and Mental Health, Institute of Mental Health, and Hunan Medical Center for Mental Health, Changsha, Hunan 410011, China. Electronic address:

Article Synopsis
  • Patients with psychotic disorders show significant issues with olfactory discrimination, indicating it may be a risk factor for developing psychosis.
  • A study compared olfactory identification and cognitive function across different groups, including those with schizophrenia, high-risk individuals, and healthy controls.
  • Results revealed that first-episode schizophrenia patients and ultra-high-risk individuals had notable deficits in olfactory identification compared to healthy individuals, and a decline in olfactory ability was more pronounced in those who later transitioned to psychosis.
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Altered HCAR3 expression may underlying the blunted niacin responses of the psychiatric disorders and the risk of schizophrenia.

Psychiatry Clin Neurosci

February 2024

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.

Aim: Blunted niacin response (BNR) was an endophenotype of schizophrenia, but the underlying mechanism remains unclarified. The objective of this study was to verify whether genes associated with BNR pathway constitute the genetic basis and the pathological mechanism of BNR phenotypic psychiatric patients.

Methods: Two independent sample sets consisting of 971 subjects were enrolled in this study.

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Investigating and comparing the psychometric properties of the Chinese Mandarin version of social responsiveness scale-2 and its shortened version in preschool-age children with autism spectrum disorder.

Asian J Psychiatr

January 2023

National Clinical Research Center for Mental Disorders, Department of Psychiatry and Hunan Medical Center for Mental Health, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China. Electronic address:

We aimed to investigate and compare the psychometric properties of the Chinese Mandarin Social Responsiveness Scale-2 (SRS-2) and its shortened version. The study assessed 670 children with autism spectrum disorder (ASD) aged 30-54 months and 138 typical developmental (TD) children of the same age in mainland China. Our item reliability test revealed that only 36 items of the 65 items in the Chinese Mandarin SRS-2 (Preschool) met the reliability criteria.

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The global pandemic COVID-19 has led to an increase in the number of people purchasing food online, which has brought to a higher demand on the food supply chain. Such as the need to collect more information related to food safety and quality in real-time. Strengthening management of food logistics information flow can reduce food loss and waste and bring better quality and safety of food to consumers.

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Background: The quality of life (QOL) of patients with methamphetamine use disorder (MAUD) is increasingly recognized as an important outcome. Previous studies have found that impulsivity is negatively associated with QOL in mental disorders, but this relationship is rarely confirmed in patients with MAUD. We hypothesized that impulsivity is negatively correlated with QOL in patients with MAUD based on previous findings.

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