56 results match your criteria: "and Hebrew University Faculty of Medicine[Affiliation]"

Association between night-time extubation and clinical outcomes in adult patients: A systematic review and meta-analysis.

Eur J Anaesthesiol

February 2022

From the Department of Surgical, Oncological and Oral Science, University of Palermo (MI, GC, SMR, CG, AG, AC), the Department of Anaesthesia, Intensive Care and Emergency, Policlinico Paolo Giaccone (PI, SMR, AG, AC), Fondazione 'Giglio' Cefalù, Palermo, Italy (CG), the Intensive Care Unit of the Shaare Zedek Medical Medical Centre and Hebrew University Faculty of Medicine, Jerusalem, Israel (SE).

Background: Whether night-time extubation is associated with clinical outcomes is unclear.

Objective: The aim of this systematic review and meta-analysis was to evaluate the association between night-time extubation and the reintubation rate, mortality, ICU and in-hospital length of stay in adult patients, compared with daytime extubation.

Design: A systematic review and meta-analysis.

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Background: We examine the impact of a 5-day online elective course in integrative medicine (IM) taking place during the COVID-19 pandemic, attended by 18 medical students from two faculties of medicine in Israel.

Methods: The course curriculum addressed effectiveness and safety of IM practices highlighting supportive and palliative care, demonstrated the work of integrative physicians (IPs) in designing patient-tailored treatments and taught practical skills in communication regarding IM. Group discussions were conducted via Zoom with 32 physicians, healthcare practitioners and IM practitioners working in integrative academic, community and hospital-based settings, in Israel, Italy, UK and Germany.

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Vasopressor and inotrope treatment for septic shock: An umbrella review of reviews.

J Crit Care

October 2021

Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.), University of Palermo, Italy; Department of Anaesthesia, Intensive Care and Emergency, Policlinico Paolo Giaccone, Palermo, Italy.

Purpose: To review the characteristics, findings and quality of systematic reviews (SRs) on the effect of any vasopressor/inotrope on outcomes in adult patients with sepsis compared with either no treatment, another vasopressor or inotrope or fluids.

Materials And Methods: We systematically searched Cochrane Central Register of Controlled Trials, PubMed and Embase (January 1993-March 2021). Descriptive statistics were used.

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Mortality after in-hospital cardiac arrest in patients with COVID-19: A systematic review and meta-analysis.

Resuscitation

July 2021

Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.), University of Palermo, Italy; Department of Anaesthesia, Intensive Care and Emergency, Policlinico Paolo Giaccone, Palermo, Italy. Electronic address:

Aim: To estimate the mortality rate, the rate of return of spontaneous circulation (ROSC) and survival with favorable neurological outcome in patients with COVID-19 after in-hospital cardiac arrest (IHCA) and attempted cardiopulmonary resuscitation (CPR).

Methods: PubMed, EMBASE, Web of Science, bioRxiv and medRxiv were surveyed up to 8th February 2021 for studies reporting data on mortality of patients with COVID-19 after IHCA. The primary outcome sought was mortality (in-hospital or at 30 days) after IHCA with attempted CPR.

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The role of post allogeneic stem-cell transplantation (AlloSCT) FLT3 inhibition for acute myeloid leukemia in the real-world setting is unclear, especially in the era of widespread pre-transplant use of tyrosine kinase inhibitors (TKIs). In a multicenter nationwide study, we assessed 41 patients who were treated with post-transplant TKIs (sorafenib,  = 23, midostaurin,  = 18). The majority also received TKIs pre-transplant ( = 32, 79%).

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COVID-19 gender susceptibility and outcomes: A systematic review.

PLoS One

November 2020

Department of Anesthesiology and Intensive Care Unit, Nord Hospital, Assistance Publique Hôpitaux Universitaire de Marseille, Aix Marseille University, Marseille, France.

Background: Epidemiological differences between men and women have been reported with regards to sepsis, influenza and severe coronavirus infections including SARS-CoV and MERS-CoV.

Aim: To systematically review the literature relating to men versus women on SARS-CoV-2 in order to seek differences in disease characteristics (e.g.

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Fabry Disease in Young Ischemic Stroke Patients in Northern Israel.

J Stroke Cerebrovasc Dis

December 2020

Medical Genetics Institute, ZOHAR PGD Unit, Shaare Zedek Medical Center and Hebrew University Faculty of Medicine, Jerusalem, Israel. Electronic address:

Introduction: The prevalence of Fabry Disease (FD) with cerebrovascular complications varies in different populations. The aim of this study was to estimate the presence of FD among young stroke patients in northern Israel.

Patients And Methods: We performed a retro-/prospective search for FD in young patients (aged ≤50 years old) admitted to the Department of Neurology due to acute ischemic stroke of any etiology.

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Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review.

Pulmonology

January 2021

Department of Anesthesiology and Intensive Care, Humanitas Clinical and Research Center - IRCCS, Milan, Italy; Department of Biomedical Science, Humanitas University, Milan, Italy. Electronic address:

Background: Tocilizumab is an IL-6 receptor-blocking agent proposed for the treatment of severe COVID-19. The aim of this systematic review was to describe the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy and safety.

Methods: MEDLINE, PubMed, EMBASE, pre-print repositories (bioRxiv and medRxiv) and two trial Registries were searched for studies on the use of tocilizumab in COVID-19 or SARS-CoV-2 infection, viral pneumonia, and/or sepsis until 20th June 2020.

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Purpose: To assess efficacy and safety of chloroquine (CQ)/hydroxychloroquine (HCQ) for treatment or prophylaxis of COVID-19 in adult humans.

Materials And Methods: MEDLINE, PubMed, EMBASE and two pre-print repositories (bioRxiv, medRxiv) were searched from inception to 8th June 2020 for RCTs and nonrandomized studies (retrospective and prospective, including single-arm, studies) addressing the use of CQ/HCQ in any dose or combination for COVID-19.

Results: Thirty-two studies were included (6 RCTs, 26 nonrandomized, 29,192 participants).

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Lung Cancer in Israel.

J Thorac Oncol

April 2020

The Legacy Heritage Oncology Center & Dr. Larry Norton Institute, Soroka Medical Center & Ben-Gurion University, Beer-Sheva, Israel. Electronic address:

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Noninvasive respiratory support in the hypoxaemic peri-operative/periprocedural patient: a joint ESA/ESICM guideline.

Intensive Care Med

April 2020

Department of Paediatric and Obstetric Anaesthesia, Juliane Marie Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Hypoxaemia is a potential life-threatening yet common complication in the peri-operative and periprocedural patient (e.g. during an invasive procedure at risk of deterioration of gas exchange, such as bronchoscopy).

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Noninvasive respiratory support in the hypoxaemic peri-operative/periprocedural patient: A joint ESA/ESICM guideline.

Eur J Anaesthesiol

April 2020

From the Aix Marseille Université, Assistance Publique Hôpitaux de Marseille, Hôpital Nord, Service d'Anaesthésie et de Réanimation, Marseille, France (ML); Intensive Care Unit of the Shaare Zedek Medical Medical Centre and Hebrew University Faculty of Medicine, Jerusalem, Israel (SE); Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa and Department of Anaesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa (LB); Anestesia e Rianimazione, Ospedale San Paolo - Polo Universitario, ASST Santi Paolo e Carlo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Centro Ricerca Coordinata di Insufficienza Respiratoria, Università degli Studi di Milano, Milan, Italy (DC); General ICUs. Department of Anaesthesia and Critical Care, Pitié-Salpêtrière Hospital, 97 Bd de l'Hopital 7013 Paris, Sorbonne University Medicine, Paris, France (JMC); Anestesia e Rianimazione, Ospedale San Paolo - Polo Universitario, ASST Santi Paolo e Carlo, Milan (SC); Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.), Section of Anaesthesia, Analgesia, Intensive Care and Emergency, Policlinico Paolo Giaccone, University of Palermo, Palermo (AC); Department of Surgical and Biomedical Sciences, University of Perugia, Perugia (EDR); Anestesia e Rianimazione, Ospedale San Paolo - Polo Universitario, ASST Santi Paolo e Carlo, Milan, Italy (SF); Pulmonary Engineering Group, Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany (MGA); Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.). Section of Anaesthesia, Analgesia, Intensive Care and Emergency, Policlinico Paolo Giaccone, University of Palermo, Palermo, Italy (CG); The Intensive Care Unit of the Shaare Zedek Medical Center, Jerusalem, Israel (YH); Saint Eloi ICU, Montpellier University Hospital and PhyMedExp, INSERM, CNRS, Montpellier, France (SJ); University Department of Medical, Oral and Biotechnological Sciences, Gabriele d'Annunzio University of Chieti-Pescara and Clinical Department of Anaesthesiology and Intensive Care Medicine, SS. Annunziata Hospital, Chieti (SMM); Anaesthesia and Intensive Care Clinic, AOU Policlinico Vittorio Emanuele, Catania (JM); Department of Surgical Sciences and Integrated Diagnostics, University of Genoa and Department of Anaesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa (PP); Department of Anaesthesia and Postoperative Intensive Care, AORN Cardarelli, Naples (GMR); Anaesthesia and Intensive Care Clinic, AOU Policlinico Vittorio Emanuele, Catania, Italy (MS); Department of Paediatric and Obstetric Anaesthesia, Juliane Marie Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark (AA).

: Hypoxaemia is a potential life-threatening yet common complication in the peri-operative and periprocedural patient (e.g. during an invasive procedure with risk of deterioration of gas exchange, such as bronchoscopy).

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False signals and therapeutic optimism have led medicine down many a wrong pathway. Apart from the unnecessary costs of care and redundant research expenditure and efforts this has caused, therapies which were eventually discontinued may have come at a staggering cost of lives lost. Still most statistical information in the medical literature is presented with its p-values and little else.

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Objective: To develop a template for uniform reporting of standardized measuring and describing of care provided in the emergency department (ED).

Methods: An international group of experts in emergency medicine, with broad experience from different clinical settings, met in Utstein, Norway. Through a consensus process, a limited number of measures that would accurately describe an ED were chosen and a template was developed.

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Article Synopsis
  • Procalcitonin (PCT) is a blood test that helps doctors understand infections, but it's unclear if it can tell the difference between two types: candidemia and bacteremia.
  • Researchers looked at 16 studies with over 45,000 patients and found that using PCT might show lower levels in candidemia than in bacteremia.
  • However, the results were not strong enough to rely on PCT alone for decision-making about antifungal treatments, and more research is needed to use it safely with other tests.
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Prophylaxis and Treatment in Critically Ill Patients after Abdominal Surgery: A Survey of Practice.

Surg Infect (Larchmt)

September 2019

5Service d'Anesthésie et de Réanimation, Chemin des Bourrely, Hôpital Nord, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.

To survey current intensive care unit (ICU) practice in initiating antifungal therapy for prophylaxis and treatment of suspected candidiasis after abdominal surgery. The goal was to establish the need to prioritize research toward standardized care of such patients. Online questionnaire survey of clinical practice based on theoretical case scenarios.

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Background: The use of in vitro fertilization is increasing. The incidence of adverse outcomes is greater for women who undergo in vitro fertilization, potentially leading to intensive care unit admission. This study aimed to assess the etiology and course of intensive care unit admission in women who underwent in vitro fertilization compared to those who did not, with specific focus on intensive care unit admission due to postpartum hemorrhage.

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In Response.

Anesth Analg

October 2018

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, Department of Anaesthesia and Pre-hospital Emergency Medicine, Birmingham Children's Hospital, Birmingham, United Kingdom Department of Anesthesiology, Shaare Zedek Medical Center and Hebrew University Faculty of Medicine, Jerusalem, Israel Departments of General Anesthesiology and Outcomes Research, Cleveland Clinic, Cleveland, Ohio Department of Anesthesiology, Columbia University, College of Physicians and Surgeons, New York, New York Department of Anesthesiology, Medicine, Surgery & Neurology, New York University, New York, New York Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee Department of Anesthesiology, The University of Illinois at Chicago, Chicago, Illinois Department of Anesthesiology, University of Pennsylvania, Philadelphia, Pennsylvania Sheridan Healthcare, Miami, Florida Department of Anesthesia, Dalhousie University, Halifax, Nova Scotia, United Kingdom Department of Critical Care Medicine, University of Chicago, Chicago, Illinois.

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Background: Care of pregnant women with concurrent medical conditions can be optimized by multidisciplinary antenatal management. In the current study we describe women with concurrent medical conditions who attended our antenatal anesthesia clinic over a 14-year period, 2002-2015 and, based on the findings, we suggest new policies, strategies and practices to improve antenatal care.

Methods: In 2002, an antenatal anesthesia clinic was established in Hadassah Medical Center.

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Management of invasive candidiasis and candidaemia in critically ill adults: expert opinion of the European Society of Anaesthesia Intensive Care Scientific Subcommittee.

J Hosp Infect

April 2018

Multidisciplinary Intensive Care, St James's University Hospital, Department of Clinical Medicine, Trinity College, Wellcome Trust-HRB Clinical Research Facility, St James Hospital, Dublin, Ireland. Electronic address:

Objective: The global burden of invasive fungal disease is increasing. Candida albicans remains the leading cause of fungal bloodstream infections, although non-albicans candidal infections are emerging. Areas of controversy regarding diagnosis and management are hampering our ability to respond effectively to this evolving threat.

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Spinal anaesthesia for elective caesarean section is associated with maternal hypotension, secondary to alteration of sympathetic tone and hypovolemia, in up to 70% of cases. Measurement of the subaortic variation in the velocity time integral (VTI) after passive leg raising allows prediction of fluid responsiveness. Our objective, in this prospective single-centre observational study, was to assess the ability of change in VTI after 45° passive leg raising to predict hypotension after spinal anaesthesia.

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Is short always important?

Heart Rhythm

February 2018

Meir Medical Center, Kefar Sava, Israel, and Hebrew University Faculty of Medicine, Jerusalem, Israel. Electronic address:

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