The Neuroplastic Outcomes from Impaired Sensory Expectations (NOISE) hypothesis: How ACL dysfunction impacts sensory perception and knee stability.

Background: The anterior cruciate ligament (ACL) is integral to maintaining knee joint stability but is susceptible to rupture during physical activity. Despite surgical restoration of passive or mechanical stability, patients struggle to regain strength and prior level of function. Recent efforts have focused on understanding how ACL-related changes in the nervous system contribute to deficits in sensorimotor control following injury and reconstruction.

Multigenerational impact of chronic exposure to mercury chloride on maternal care, puberty, fertility, and hypothalamic function in female mice.

Chronic exposure to low doses of mercury, one of the ten most dangerous chemicals for public health, has been associated with problems in fertility. Our study aims to investigate the effect of chronic exposure to a low dose of mercury chloride on the reproductive health of female mice and maternal behavior throughout generations using the maternal lineage for the first and second generations, either by direct exposure with F1 and F2 or via the germ cells with F2'. To our knowledge, these modalities have never been addressed before.

ChimpanSEE, ChimpanDO: Grooming and play contagion in chimpanzees.

Behavioural contagion-the onset of a species-typical behaviour soon after witnessing it in a conspecific-forms the foundation of behavioural synchrony and cohesive group living in social animals. Although past research has mostly focused on negative emotions or neutral contexts, the sharing of positive emotions in particular may be key for social affiliation. We investigated the contagion of two socially affiliative interactive behaviours, grooming and play, in chimpanzees.

Surgical Management of Epidermoid Cysts of Scalp: A Case Report.

Epidermoid cysts represent a common benign cutaneous neoplasm resulting from the invagination and subsequent proliferation of epidermal cells within the dermal layer. They exhibit a predilection for the face, cervical region, upper torso, and scalp, manifesting as firm, mobile nodules with a characteristic central punctum. Surgical excision is the recommended therapeutic approach for sizeable or recurrent cysts, particularly when they elicit discomfort or aesthetic concerns.

Higher eigenvector centrality in grooming network is linked to better inhibitory control task performance but not other cognitive tasks in free-ranging Japanese macaques.

The Social Intelligence Hypothesis predicts that complex social environments promote higher cognitive capacities. This hypothesis is often tested by comparing species or conspecific groups with varying group sizes or social structures. However, individual social environments differ not only among species or groups but also within the same group.

Unveiling genetic defense mechanisms: expression analysis of hym, AmNrx1, and CYP9Q3 genes in Varroa-resistant anatolian honey bees.

The Varroa destructor represents a significant threat to honey bees, leading to substantial yield losses and declines in colony health. Defense behaviors, including grooming (auto and allogrooming), serve as crucial mechanisms against Varroa infestations, yet the genetic basis of these behaviors remains elusive. This study examines the expression levels of hymenoptaecin (hym), neurexin-1 (AmNrx1), and CYP9Q3, potentially associated with defense behavior, in colonies of the Muğla honey bee ecotype (Apis mellifera anatoliaca) subjected to a Varroa selection program.

Examining the Role of Community Engagement in Enhancing the Participation of Racial and Ethnic Minoritized Communities in Alzheimer's Disease Clinical Trials; A Rapid Review.

Background: Despite higher dementia prevalence in racial and ethnic minoritized communities, they are underrepresented in Alzheimer's disease clinical trials. Community-based recruitment strategies are believed to yield positive outcomes in various fields, such as cancer and cardiovascular clinical trials, but their outcomes in Alzheimer's disease and Related Dementias (AD/ADRD) require further study. In this systematic rapid review, we synthesized the available evidence on community-engaged recruitment strategies in enhancing participation in AD/ADRD clinical trials and observational study participation.

Foot Reflexology with Caring Consciousness to Reduce Pain in Older Adults: An Integrative Review.

To analyze the evidence available on foot reflexology with application of caring consciousness to reduce pain in older adults Integrative review carried out in Medline/PubMed, CINAHL, EBSCO Host, SCOPUS, Web of Science, and EMBASE databases using the MESH terms "Aged," "Pain," "Musculoskeletal manipulations," "Nursing," and "Nursing theory." in English, Spanish, Portuguese, and French published between 2012 and 2022. The selected studies were exported to Rayyan software and evaluated by title and abstract; after reading the full text, were analyzed according to the PRISMA guide checklist.

Exploring the anti-depressant effects and nitric oxide modulation of quercetin: A preclinical study in Socially Isolated mice.

Objectives: This study investigates the effects of quercetin, an antioxidant and nitric oxide (NO) modulator, on depressive-like behaviours triggered by social isolation stress (SIS) in mice. SIS, known to harm psychosocial functioning and increase the risk of depression, involves oxidative stress and NO in its pathophysiology.

Methods: 72 male mice were divided into nine groups, including the social (SC) group as the control group (stress-free with normal saline intake).

Dynamic changes in the hippocampal memory index and biochemical indices in Sprague Dawley rats exposed to intrauterine kola nut.

Kola nut is commonly consumed by pregnant women to suppress symptoms of morning sickness. This study investigated the effects of kola nut on the biochemical indices of the hippocampus and its dependent memory. Kola nut extract was fed to pregnant dams from the first day of their pregnancy until parturition.

An educational intervention to enhance self-care practices among 1st year dental students- a mixed method study design.

Background: Prevalence of rising stress among medical students has been reported widely and may jeopardize patient interaction and care. Evolving medical education needs to demonstrate compassionate self-care practices to enhance mental well-being of students. Although numerous researches have highlighted the stressors and coping strategies but no structured educational intervention has been reported so far among medical students of Pakistan.

How to make land use policy decisions: Integrating science and economics to deliver connected climate, biodiversity, and food objectives.

Land use change is crucial to addressing the existential threats of climate change and biodiversity loss while enhancing food security [M. Zurek , , 1416-1421 (2022)]. The interconnected and spatially varying nature of the impacts of land use change means that these challenges must be addressed simultaneously [H.

The Role of Perpetrator Attractiveness and Relationship Dynamics on Perceptions of Adolescent Sexual Grooming.

Sexual grooming, exacerbated by increased internet and social media usage , is a growing concern. Past researchers have found differences in perceptions of sexual grooming based on gender-pairing, perpetrator attractiveness, as well as perpetrator and victim age and gender. Our study extends this research by exploring how the attractiveness of the perpetrator and their relationship to the victim - specifically, whether they are a teacher, religious leader, or family friend - affects perceived grooming severity and recommended legal response.

Segmental phase angles as predictors of functional recovery and activities of daily living in patients after stroke.

Background: This study investigated the association between segmental phase angles and functional outcomes in patients after stroke, hypothesizing that increased segmental phase angle correlates with improved functional status.

Methods: A retrospective cohort study of 1012 patients after stroke was conducted. Whole body and segmental phase angles were measured using bioelectrical impedance analysis within 3 days of admission.

Deep learning algorithms reveal increased social activity in rats at the onset of the dark phase of the light/dark cycle.

The rapid decrease of light intensity is a potent stimulus of rats' activity. The nature of this activity, including the character of social behavior and the composition of concomitant ultrasonic vocalizations (USVs), is unknown. Using deep learning algorithms, this study aimed to examine the social life of rat pairs kept in semi-natural conditions and observed during the transitions between light and dark, as well as between dark and light periods.

Improving Reproductive Success in Captive Marmosets Through Active Female Choice.

The recent upsurge in the use of common marmosets (Callithrix jacchus) as a desirable model for high-priority biomedical research has challenged local and global suppliers struggling to provide sufficient numbers of marmosets for large-scale projects. In laboratories, random male-female pairings are often unsuccessful, with intervals of several months before attempting alternate pairings. Here we address this challenge through a behavioral task that promotes self-directed female selection of potential mates to increase the efficiency of breeding in captive marmosets.

Commentary: Using QbTest for monitoring pharmacological treatment response in ADHD - are we there yet?

Individuals with attention-deficit/hyperactivity disorder (ADHD) exhibit varied responses to pharmacological treatments (e.g. stimulants and non-stimulants).

Effect of the social environment on olfaction and social skills in wild-type and a mouse model of autism.

Autism spectrum disorders (ASD) are complex, polygenic and heterogenous neurodevelopmental conditions. The severity of autism-associated variants is influenced by environmental factors, particularly social experiences during the critical neurodevelopmental period. While early behavioral interventions have shown efficacy in some children with autism, pharmacological support for core features - impairments in social interaction and communication, and stereotyped or restricted behaviors - is currently lacking.

Neurocognitive & Ecological Motor Learning Considerations for the 11+ ACL Injury Prevention Program: A Commentary.

The 11+ is a structured warm-up program designed to prevent injuries in soccer players, but has proven efficacy in many populations, settings and sports. It consists of 15 exercises that target the most common injury sites, such as the knee, ankle, and groin. However, the implementation and adherence of the 11+ remain suboptimal, and recent compelling data indicates underlying mechanisms of injury risk related to neural control of movement may not be adequately targeted.

Psilocybin reduces grooming in the SAPAP3 knockout mouse model of compulsive behaviour.

Psilocybin is a serotonergic psychedelic compound which shows promise for treating compulsive behaviours. This is particularly pertinent as compulsive disorders require research into new pharmacological treatment options as the current frontline treatments such as selective serotonin reuptake inhibitors, require chronic administration, have significant side effects, and leave almost half of the clinical population refractory to treatment. In this study, we investigated psilocybin administration in male and female SAPAP3 knockout (KO) mice, a well-validated mouse model of obsessive compulsive and related disorders.

Reduced on-line speech gesture integration during multimodal language processing in adults with moderate-severe traumatic brain injury: Evidence from eye-tracking.

Background: Language is multimodal and situated in rich visual contexts. Language is also incremental, unfolding moment-to-moment in real time, yet few studies have examined how spoken language interacts with gesture and visual context during multimodal language processing. Gesture is a rich communication cue that is integrally related to speech and often depicts concrete referents from the visual world.