8 results match your criteria: "and Faculty of Medicine of the University of Porto[Affiliation]"
What do we know about abnormally low prolactin levels in polycystic ovary syndrome? A narrative review.
Rev Endocr Metab Disord
December 2024
Faculty of Medicine, University of Porto, Porto, Portugal.
Article Synopsis
- Hyper and hypoprolactinemia are linked to metabolic changes in patients with PCOS, with prolactin levels having a protective effect against metabolic issues like insulin resistance and obesity.
- Four studies specifically looked at hypoprolactinemia in PCOS, while six additional studies reported low prolactin levels, though the overall prevalence is relatively low (13.2-13.9%).
- There is a need for more research, including prospective studies and clinical trials, to explore treatments targeting both high and low prolactin levels in PCOS patients.
The right heart in patients with cancer. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Council of Cardio-Oncology.
Eur J Heart Fail
October 2024
Cardiology, San Raffaele Cassino, Cassino, Italy.
European survey of diagnosis and management of the polycystic ovary syndrome: full report on the ESE PCOS Special Interest Group's 2023 Questionnaire.
Eur J Endocrinol
August 2024
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Article Synopsis
- PCOS is a common hormonal disorder with diagnostic and management complexities, prompting a study on European endocrinologists' understanding of it.
- An online survey of 505 endocrinologists revealed that 85% use the Rotterdam criteria for diagnosis, with most patient referrals occurring between ages 20 and 40.
- The findings highlight the importance of metabolic profiling and lifestyle changes in managing PCOS, along with consensus on using treatments like metformin and oral contraceptives.
Morphologic Heterogeneity of Carcinoma with Signet Ring Cell Features at Different Primary Sites.
Pathobiology
August 2024
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Introduction: Signet ring cells (SRCs) may be observed in carcinomas from multiple primary sites. Elucidating unknown primaries from metastases with SRCs represents a diagnostic challenge. This study examined morphologic characteristics of adenocarcinomas with SRCs from stablished primary sites and described objective features, which can aid in identifying the site of origin.
View Article and Find Full Text PDFConservative Treatment and Percutaneous Pain Relief Techniques in Patients with Lumbar Spinal Stenosis: WFNS Spine Committee Recommendations.
World Neurosurg X
July 2020
Neurosurgery Department, Humanitas Research Hospital, Rozzano, Milan, Italy.
Background: Degenerative lumbar spinal stenosis (LSS) is a progressive disease with potentially dangerous consequences that affect quality of life. Despite the detailed literature, natural history is unpredictable. This uncertainty presents a challenge making the correct management decisions, especially in patients with mild to moderate symptoms, regarding conservative or surgical treatment.
View Article and Find Full Text PDFAre the Outcomes of Minimally Invasive Transforaminal/Posterior Lumbar Fusion Influenced by the Patient's Age or BMI?
Clin Spine Surg
August 2020
Department of Neurosurgery, Kepler Universitätsklinik Neuromed Campus, Johannes Kepler University Linz, Linz, Austria.
Study Design: A retrospective subgroup analysis of a prospective observational study was carried out.
Summary Of Background Data: Patients' baseline characteristics may influence the clinical outcomes after minimally invasive lumbar interbody fusion (MILIF).
Objective: This study aimed to investigate the influence of patient's age and body mass index (BMI) on the clinical outcomes of MILIF for degenerative lumbar disorder.
Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium.
Nat Mater
October 2014
1] School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts 02115, USA.
In vitro models of normal mammary epithelium have correlated increased extracellular matrix (ECM) stiffness with malignant phenotypes. However, the role of increased stiffness in this transformation remains unclear because of difficulties in controlling ECM stiffness, composition and architecture independently. Here we demonstrate that interpenetrating networks of reconstituted basement membrane matrix and alginate can be used to modulate ECM stiffness independently of composition and architecture.
View Article and Find Full Text PDFTriple-orifice congenital stenotic mitral valve: a unique finding characterized by multimodality echocardiography.
Eur J Echocardiogr
October 2011
Cardiology Department, Hospital São João, and Faculty of Medicine of the University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.