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Ultrasound Tomography Evaluation of Breast Density: A Comparison With Noncontrast Magnetic Resonance Imaging.
Invest Radiol
June 2017
From the *Cancer Research UK Cancer Imaging Centre; †Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust; ‡Royal Marsden NHS Foundation Trust; §Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom; ∥Delphinus Medical Technologies, Karmanos Cancer Institute, Wayne State University, Detroit, MI; and ¶Division of Genetics and Epidemiology, and Division of Breast Cancer Research Institute of Cancer Research, London, United Kingdom.
Objectives: Ultrasound tomography (UST) is an emerging whole-breast 3-dimensional imaging technique that obtains quantitative tomograms of speed of sound of the entire breast. The imaged parameter is the speed of sound which is used as a surrogate measure of density at each voxel and holds promise as a method to evaluate breast density without ionizing radiation. This study evaluated the technique of UST and compared whole-breast volume averaged speed of sound (VASS) with MR percent water content from noncontrast magnetic resonance imaging (MRI).
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