Meta-analysis of neuropsychological functioning in euthymic bipolar disorder: an update and investigation of moderator variables.

Objectives: Cognitive impairment is frequently observed among individuals with bipolar disorder during acute and euthymic phases of the illness. The purpose of this study was to provide an updated meta-analysis on the neuropsychological functioning of euthymic bipolar disorder individuals and to explore study design, demographic, and clinical variables that could moderate observed effects.

Methods: Searches were conducted on Medline and PsychInfo databases and 28 studies were selected that met inclusion criteria.