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Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk.

Ann Intern Med

July 2018

Center for Primary Care and Outcomes Research and Center for Population Health Sciences at Stanford University, Stanford, California, and Center for Primary Care at Harvard Medical School, Boston, Massachusetts (S.B.).

Background: The 2013 pooled cohort equations (PCEs) are central in prevention guidelines for cardiovascular disease (CVD) but can misestimate CVD risk.

Objective: To improve the clinical accuracy of CVD risk prediction by revising the 2013 PCEs using newer data and statistical methods.

Design: Derivation and validation of risk equations.

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