4 results match your criteria: "and Blood Institute Bethesda MD USA.[Affiliation]"

Background: Extracellular microRNAs (miRNAs) are a class of noncoding RNAs that remain stable in the extracellular milieu, where they contribute to various physiological and pathological processes by facilitating intercellular signaling. Previous studies have reported associations between miRNAs and cardiovascular diseases (CVDs); however, the plasma miRNA signatures of CVD and its risk factors have not been fully elucidated at the population level.

Methods And Results: Plasma miRNA levels were measured in 4440 FHS (Framingham Heart Study) participants.

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Article Synopsis
  • * In the ISCHEMIA trial, women had similar catheterization rates but significantly lower revascularization rates than men (73.4% vs. 81.2%, respectively).
  • * Despite these differences, there were no significant disparities in primary outcomes like cardiovascular death and myocardial infarction between women and men, indicating that both sexes responded similarly to treatment.
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Background Among patients with heart failure (HF), social risk factors (SRFs) are associated with poor outcomes. However, less is known about how co-occurrence of SRFs affect all-cause health care utilization for patients with HF. The objective was to address this gap using a novel approach to classify co-occurrence of SRFs.

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Objective: This study examined the cross-sectional and longitudinal relationships of built environment characteristics with adiposity and glycaemic measures.

Method: Longitudinal study sample consisted of 4,010 Framingham Heart Study Offspring (baseline: 1998-2001; follow-up: 2005-2008) and Generation Three (baseline: 2002-2005; follow-up: 2008-2011) participants (54.8% women, baseline mean age 48.

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