Vitiligo patients experience barriers in accessing care.

Vitiligo is a loss of pigment occurring in approximately 0.4% to 2% of the worldwide population. The aim of this study was to determine and characterize barriers to access of care in US patients with vitiligo.

Phototherapy for atopic dermatitis.

Phototherapy is a second-line treatment for moderate to severe atopic dermatitis (AD) that effectively decreases cutaneous inflammation with minimal or no systemic side effects. Children in grade school, adolescents, and adults may benefit from phototherapy, when they have chronic AD refractory to first-line topical treatments. This review focuses on six approaches for phototherapy in AD: (1) broadband ultraviolet B (UVB), (2) Goeckerman regimen (coal tar + broadband UVB), (3) narrowband UVB, (4) excimer lasers for targeted areas, (5) combination UVA/UVB, and (6) UVA-1.

Pediatric rosacea.

Because rosacea is uncommon in the pediatric population, care must be taken to exclude other papulopustular disorders. Children can present with vascular, papulopustular, and/or ocular findings. Importantly, ocular symptoms can appear before the cutaneous symptoms of rosacea, leading to misdiagnosis.

A practical overview of pediatric atopic dermatitis, part 3: differential diagnosis, comorbidities, and measurement of disease burden.

Atopic dermatitis (AD) is a multisystem disorder that has wide-reaching comorbidities and may mimic a variety of skin conditions. In the third part of this series, the differential diagnosis of pediatric AD including possible clinical mimics is discussed as well as the many recently identified comorbidities of pediatric AD, including psychosocial and allergic diseases.

A Practical Approach to the Diagnosis and Treatment of Vitiligo in Children.

Vitiligo is a common inflammatory skin disease with a worldwide prevalence of 0.5% to 2.0% of the population.

A practical overview of pediatric atopic dermatitis, part 2: triggers and grading.

In part 2 of this 3-part series on atopic dermatitis (AD) in children, triggers for the appearance and flaring of AD are reviewed. The role of AD in the atopic march is explored. Furthermore, the usage of grading systems in the development of therapeutics and in clinical care is discussed.

A practical overview of pediatric atopic dermatitis, part 1: epidemiology and pathogenesis.

Atopic dermatitis (AD) is a multisystem inflammatory disorder that is part of the spectrum of atopy, a series of conditions in which hyperreactivity and allergic symptoms are triggered by a series of causes including environmental allergens and irritants. Atopic dermatitis affects approximately one-quarter of children in developed countries and can have a negative impact on quality of life. In part 1 of this series addressing AD, the epidemiology and pathogenesis of AD are reviewed with an overview of skin barrier function.

Diet and atopic dermatitis.

Dermatologists and pediatric dermatologists frequently treat patients with atopic dermatitis (AD), and patients and guardians often associate AD with food allergies. A common misconception is that dietary restrictions will resolve the disease. The role of diet is evolving in the discussion of AD.

The "Jewelry Addict": Allergic Contact Dermatitis from Repetitive Multiple Children's Jewelry Exposures.

A 9-year-old girl with atopic dermatitis developed persistent plaques on the lips, hands, and fingers that were unresponsive to topical steroids. Her mother reported that she was "addicted" to costume jewelry and developed rashes in reaction to a number of adornments, ranging from rubber bracelets to costume metal jewelry and belt buckles. A careful history of jewelry exposures was taken and patch testing was performed to identify allergenic sources.

Assessment of atopic dermatitis using self-report and caregiver report: a multicentre validation study.

Background: The epidemiology of atopic dermatitis (AD) in the U.S.A.

Complementary and alternative medicines and childhood eczema: a US population-based study.

The prevalence of complementary and alternative medicine (CAM) use in US children with eczema is unknown. Furthermore, it is unknown whether CAM use in the United States is associated with higher eczema prevalence. We sought to determine the eczema prevalence in association with CAM usage.

Pediatric dermatology training survey of United States dermatology residency programs.

Variability exists in pediatric dermatology education for dermatology residents. We sought to formally assess the pediatric dermatology curriculum and experience in a dermatology residency program. Three unique surveys were developed for dermatology residents, residency program directors, and pediatric dermatology fellowship program directors.

Quality of life impairment in children and adolescents with vitiligo.

Vitiligo significantly affects quality of life (QOL) in adults, but little is known about the effect on QOL of pediatric vitiligo and whether the extent, distribution, and duration of vitiligo are associated with QOL. We performed an online parental questionnaire-based study (N = 350) regarding children ages 0 to 17 years with vitiligo, including validated questions about body surface area (BSA), distribution, and age of onset of vitiligo, associated symptoms, and QOL using the Children's Dermatology Life Quality Index (CDLQI). Vitiligo negatively affected numerous aspects of and total CDLQI score (median 3.

Adult eczema prevalence and associations with asthma and other health and demographic factors: a US population-based study.

Background: Little is known about the epidemiology of eczema in adults. The goal of this study was to determine the prevalence of and associations with adult eczema in the United States.

Methods: We used the 2010 National Health Interview Survey from a nationally representative sample of 27,157 adults age 18 to 85 years.

Mohs surgeons' use of topical emollients in postoperative wound care.

Background: Although there is no universally accepted topical emollient recommended for wound care, there has been a trend toward minimizing exposure to common culprits of allergic contact dermatitis.

Objective: To assess the current practices of postoperative emollient use of dermatologic surgeons.

Methods And Materials: An anonymous 10-question survey on postoperative emollient use for clean surgical wounds was e-mailed to 857 members of the American College of Mohs Surgery.

Antiphospholipid antibody syndrome secondary to trimethoprim/sulfamethoxazole.

Antiphospholipid antibody syndrome (APS) results from autoantibodies to cell surface phospholipids or phospholipid-binding proteins resulting in clotting anomalies and can have devastating sequelae, including stroke, deep venous thrombosis, pulmonary embolism, and recurrent spontaneous abortions. However, cutaneous manifestations are the first sign of APS in up to 41% of patients. We present a case report of APS that developed several days after taking trimethoprim/sulfamethoxazole.

Adjunctive trichloroacetic acid therapy enhances squaric acid response to verruca vulgaris.

Squaric acid dibutyl ester (SADBE) is a commonly used treatment for verruca vulgaris of childhood. Few studies, however, have examined the role of SADBE in combination with other topical therapies for warts. We sought to determine if trichloroacetic acid 50% (TCA) and/or cantharidin 0.

Prognostic implications of additional chromosome abnormalities among patients with de novo acute promyelocytic leukemia with t(15;17).

This retrospective study performed by the Eastern Cooperative Oncology Group and the Southwest Oncology Group enrolled 140 acute promyelocytic leukemia (APL) patients with t(15;17) to determine the influence of additional karyotypic abnormalities on treatment outcome. Karyotypes were centrally reviewed by both study groups. The complete response rate after induction for patients with t(15;17) treated with chemotherapy, or all-trans retinoic acid (ATRA) as induction therapy was not affected by additional cytogenetic aberrations.

Chickenpox in childhood is associated with decreased atopic disorders, IgE, allergic sensitization, and leukocyte subsets.

Background: Wild-type varicella zoster infection (WTVZV) up to 8 yr of age has been shown to protect against atopic dermatitis (AD) and asthma. We sought to determine whether WTVZV in childhood protects against atopic disorders, allergic sensitization or decreases serum Immunoglobulin E (IgE) levels.

Methods: We conducted a retrospective, practice-based study of outpatient pediatric practices in NY.

Association between atopic dermatitis and obesity in adulthood.

Background: Obesity in early childhood is associated with increased risk for and severity of atopic dermatitis (AD). Objective To determine whether obesity in adulthood is associated with risk of AD.

Methods: This was a retrospective case-control study of 2090 adults using questionnaire, height and weight, and skin-prick testing between January 1994 and December 2003.

Endoscopic resection of thoracic paravertebral and dumbbell tumors.

Objective: Neurogenic paravertebral tumors are uncommon neoplasms arising from neurogenic elements within the thorax. These tumors may be dumbbell shaped, extending into the spinal canal or exclusively paraspinal. Generally encapsulated, they are located in the posterior mediastinum.