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Am J Physiol
March 1999
Division of Nephrology, University of Texas Health Science Center, and Audie L. Murphy Memorial Veterans Affairs Hospital San Antonio, Texas 78284, USA.
BMP-7, a member of the bone morphogenic protein subfamily (BMPs) of the transforming growth factor-beta superfamily of secreted growth factors, is abundantly expressed in the fetal kidney. The precise role of this protein in renal physiology or pathology is unknown. A cDNA that encodes rat BMP-7 was cloned and used as a probe to localize BMP-7 mRNA expression by in situ hybridization in the adult rat kidney.
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