361 results match your criteria: "affiliated to the Sackler School of Medicine[Affiliation]"

Midterm outcomes of patients with multivessel disease treated at centers with and without on-site cardiac surgery services.

J Thorac Cardiovasc Surg

May 2022

Department of Cardiology, Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objective: The last decade has witnessed an increased number of stand-alone interventional cardiology units due to the consolidation of cardiac surgery services. We aimed to explore the impact of a heart team on the midterm outcomes of patients with multivessel coronary artery disease.

Methods: This prospective registry included 1063 consecutive patients with multivessel disease enrolled between January and April 2013 from all 22 hospitals in Israel that perform coronary angiography and percutaneous coronary intervention, with or without on-site cardiac surgery services.

View Article and Find Full Text PDF

Inguinal lymphadenopathy as a predicting factor for ipsilateral primary limb amputation after a successful endovascular treatment.

Eur J Radiol

September 2020

Departments of Diagnostic Imaging, Sheba Medical Center, Tel-Hashomer, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Purpose: To assess the correlation between inguinal lymph node characteristics and ipsilateral limb amputation rates in patients with ischemic foot ulcers after a successful endovascular treatment.

Method: A retrospective review of patients who were endovascularly treated for ischemic foot ulcers between January 2015 and May 2017. Technical success was defined as arterial recanalization with stenosis less than 30 % and ankle brachial index improvement by > 0.

View Article and Find Full Text PDF

A novel surgical technique of left atrial appendage closure.

J Card Surg

September 2020

Department of Cardiac Surgery, Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background And Aims: Surgical left atrial appendage occlusion or exclusion has been performed with various techniques, however, during the following years the left atrial appendage elimination often fails. We propose a novel, rapid surgery process of safely closing and obliterating the left atrial appendage by an intra-atrial sutureless closure.

Methods: The left atrial appendage elimination is performed by invaginating the appendage into the left atrium and tying it on the interluminal base to permanently prevent its evagination back into the normal position.

View Article and Find Full Text PDF

Recent improvement in outcomes following aortic valve replacement in low-risk patients.

J Card Surg

September 2020

Department of Cardiac Surgery, Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

View Article and Find Full Text PDF

An amendment to this paper has been published and can be accessed via the original article.

View Article and Find Full Text PDF

Atlas of the OMERACT Heel Enthesitis MRI Scoring System (HEMRIS).

RMD Open

February 2020

Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen University Hospital, Glostrup, Denmark.

Objective: Assessment of enthesitis, a key feature in spondyloarthritis (SpA) and psoriatic arthritis (PsA), using objective and sensitive methods is pivotal in clinical trials. MRI allows detection of both soft tissue and intra-osseous changes of enthesitis. This article presents an atlas for the Outcome Measures in Rheumatology (OMERACT) Heel Enthesitis Magnetic Resonance ImagingMRI Scoring System (HEMRIS).

View Article and Find Full Text PDF

TICACOS international: A multi-center, randomized, prospective controlled study comparing tight calorie control versus Liberal calorie administration study.

Clin Nutr

February 2021

Department of Intensive Care, Institute for Nutrition Research, Rabin Medical Center, Beillison Hospital, Affiliated to the Sackler School of Medicine, Tel Aviv University, Israel.

Unlabelled: Since the first TICACOS study, 3 additional studies have been published comparing a medical nutrition therapy guided by indirect calorimetry to a regimen prescribed on the basis of predictive equations. A recent guidelines document included a meta-analysis including these 4 papers and found a trend for improvement (OR 0.98-1.

View Article and Find Full Text PDF

Cardiac surgery in patients with Hemophilia:is it safe?

J Cardiothorac Surg

May 2020

The National Hemophilia Center, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Ramat-Gan, Israel.

Background: The life expectancy of hemophiliacs is similar to that of the general population. As a result, the prevalence of age-related cardiovascular diseases has increased. We present our experience with hemophilia patients who underwent cardiac surgery in our Medical Center between 2004 and 2019.

View Article and Find Full Text PDF

Outcomes of isolated surgical aortic valve replacement in the era of transcatheter aortic valve implantation.

J Card Surg

July 2020

Department of Cardiac Surgery, Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background And Aims: Until early into the 21st century, the only therapeutic option for aortic valve (AV) stenosis was surgical aortic valve replacement (AVR), but this changed with the introduction of transcatheter aortic valve implantation (TAVI). Our objective was to present the results of surgical AVR performed in low-risk patients in the era of TAVI, in a large tertiary medical center.

Methods: Data from low surgical risk patients (defined as Euroscore < 5) greater than 60 years of age, who underwent isolated AVR surgery between 2004 and 2018, were obtained from our departmental database.

View Article and Find Full Text PDF

Objectives: To investigate criteria for treatment response and remission in patients with axial SpA as assessed by whole-body magnetic resonance imaging (WB-MRI) of axial and peripheral joints and entheses during treatment with golimumab.

Methods: We performed an investigator-initiated cohort study of 53 patients who underwent WB-MRI at weeks 0, 4, 16 and 52 after initiation of golimumab. Images were assessed according to the Spondyloarthritis Research Consortium of Canada MRI SI joint inflammation index, Canada-Denmark MRI spine inflammation score and the MRI peripheral joints and entheses inflammation index.

View Article and Find Full Text PDF

Objective: The purpose of this study was to establish prognostic factors in fetuses diagnosed with periventricular pseudocysts (PVPCs) without known congenital infection, between 28 and 37 weeks of gestation.

Methods: This retrospective study included cases of fetal PVPC from 2008 to 2018. PVPCs were classified according to location, number, extension, morphology, and size.

View Article and Find Full Text PDF

Very low-dose computerized tomography for confirmation of urinary stone presence.

World J Urol

January 2021

Department of Diagnostic Imaging, Sheba Medical Center, Tel-Hashomer, affiliated to the Sackler School of Medicine, Tel-Aviv University, 52621, Tel Aviv, Israel.

Purpose: To determine whether a modified non-contrast very low-dose computed tomography (VLD-CT) protocol is applicable for confirmation of known urolithiasis.

Methods And Materials: Consecutive adult patients with a CT scan showing urinary tract stone(s) between 6/2017-12/2018 were included. They were referred to a modified VLD-CT protocol if stone presence was equivocal or if stone location needed reassessment before an endourological interventional procedure.

View Article and Find Full Text PDF

Creating Artificial Images for Radiology Applications Using Generative Adversarial Networks (GANs) - A Systematic Review.

Acad Radiol

August 2020

Department of Diagnostic Imaging, Chaim Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Emek Haela St. 1, Ramat Gan, Israel 52621; Deep Vision Lab, Sheba Medical Center, Tel Hashomer, Israel.

Rationale And Objectives: Generative adversarial networks (GANs) are deep learning models aimed at generating fake realistic looking images. These novel models made a great impact on the computer vision field. Our study aims to review the literature on GANs applications in radiology.

View Article and Find Full Text PDF

Deep Learning for Natural Language Processing in Radiology-Fundamentals and a Systematic Review.

J Am Coll Radiol

May 2020

Department of Diagnostic Imaging, Chaim Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel-Aviv University, Israel.

Purpose: Natural language processing (NLP) enables conversion of free text into structured data. Recent innovations in deep learning technology provide improved NLP performance. We aimed to survey deep learning NLP fundamentals and review radiology-related research.

View Article and Find Full Text PDF

Outcomes of Degenerative Mitral Valve Repair Surgery for Anterior, Posterior, and Bileaflet Pathology.

Ann Thorac Surg

September 2020

Department of Cardiac Surgery, Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Background: Degenerative mitral valve disease involving anterior leaflet pathology is considered less favorable regarding durability of surgical repair than isolated posterior leaflet disease. We aimed to compare the outcomes of patients undergoing mitral valve repair for anterior, posterior, and bileaflet pathologies, and to investigate predictors for repair failure.

Methods: Of the 760 consecutive patients with degenerative leaflet disease who underwent mitral valve repair, 485 (64%) had posterior, 223 (29%) had bileaflet, and 52 (7%) had anterior leaflet pathology.

View Article and Find Full Text PDF

Vaginal postcoital injuries requiring surgical intervention: a case series and literature review.

Int J Impot Res

January 2021

Department of Obstetrics and Gynecology, Yitzhak Shamir (formerly Assaf Harofe) Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

This case series describes clinical features and management of women who required surgical repair of vaginal injuries following consensual intercourse in our institution during the last decade. As a secondary aim, we reviewed the literature on the topic. We searched our institution's database for procedures coded as "Suture of Vagina," excluding trauma not related to consensual sexual activity: between January 2008 and December 2017, 20 women underwent hemostatic suturing for vaginal injuries following intercourse.

View Article and Find Full Text PDF

Dual-energy contrast-enhanced spectral mammography (CESM) for breast cancer screening.

Quant Imaging Med Surg

November 2019

Department of Diagnostic Imaging, Chaim Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Ramat Gan, Israel.

View Article and Find Full Text PDF

Purpose: To determine factors associated with early flap misalignment following microkeratome-assisted laser in situ keratomileusis.

Materials And Methods: This retrospective study included the right eyes of consecutive patients who underwent laser in situ keratomileusis procedure between 2005 and 2016 at Care-Vision Laser Centers, Tel-Aviv, Israel. Patients were divided into two groups according to whether or not they subsequently developed early flap misalignment.

View Article and Find Full Text PDF

Purpose: To describe novel findings of hyperreflective material in the silicone-retina interphase on spectral domain optical coherence tomography (SD-OCT) imaging in eyes with silicone oil tamponade.

Methods: Retrospective observational clinical study of consecutive patients who underwent primary pars plana vitrectomy with silicone oil tamponade for rhegmatogenous retinal detachment. Repeat clinical examination and spectral domain optical coherence tomography macular imaging performed 3 months after surgery were evaluated to identify any macular pathologies, including formation of epiretinal membranes, intraretinal changes, subretinal fluid, and edema before scheduled secondary vitrectomy for silicone oil removal.

View Article and Find Full Text PDF

Purpose: To compare clinical outcomes of patients undergoing first re-treatment by flap relift with those re-treated by surface ablation on the flap after an initial myopic laser-assisted in situ keratomileusis (LASIK) procedure.

Methods: This is a retrospective cohort analysis of consecutive patients who underwent myopic LASIK and required re-treatment between January 2007 and December 2016. Cases re-treated by flap relift were propensity score matched with cases re-treated by surface ablation, and clinical outcomes were compared.

View Article and Find Full Text PDF

Current noninvasive methods to detect structural plasticity in humans are mainly used to study long-term changes. Diffusion magnetic resonance imaging (MRI) was recently proposed as a novel approach to reveal gray matter changes following spatial navigation learning and object-location memory tasks. In the present work, we used diffusion MRI to investigate the short-term neuroplasticity that accompanies motor sequence learning.

View Article and Find Full Text PDF

Impact of right ventricular volumes on the outcomes of TAVR: a volumetric analysis of preprocedural computed tomography.

EuroIntervention

June 2020

Department of Cardiology, Tel Aviv Medical affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Isreal.

Aims: The aim of this study was to assess the prognostic implications of increased right ventricle volume index (RVVI) using cardiac-gated computed tomography angiography (CCTA) data among patients undergoing transcatheter valve replacement (TAVR).

Methods And Results: CCTA of 323 patients who underwent TAVR at Stanford University Medical Center (CA, USA) and Tel Aviv Medical Center (Israel) between 2013 and 2016 was analysed by an automatic four-chamber volumetric software and grouped into quartiles according to RVVI. Higher one-year mortality rates were noted for the upper quartiles - 5%, 4.

View Article and Find Full Text PDF

Optimal Head Position Following Intratympanic Injections of Steroids, As Determined by Virtual Reality.

Otolaryngol Head Neck Surg

December 2019

Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objectives: To study optimal head position after intratympanic steroid injections to enhance drug bioavailability.

Study Design: Application of virtual and in vitro models of the intratympanic anatomy.

Setting: The surgical 3-dimensional printing laboratory of a tertiary academic medical center.

View Article and Find Full Text PDF

Robot-assisted Laparoscopic Extravesical Cross-trigonal Ureteral Reimplantation With Tailoring for Primary Obstructive Megaureter.

Urology

December 2019

Departments of Urology and Pediatric Urology, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.

Objective: To describe a novel, minimally invasive surgical technique, robotic-assisted laparoscopic dismembered extravesical cross-trigonal ureteral reimplantation for primary obstructive megaureter and to report a case series of 13 patients.

Methods: Thirteen patients between the ages of 10 and 96 months who were diagnosed with primary obstructive megaureter underwent robotic-assisted laparoscopic dismembered extravesical cross-trigonal ureteral reimplantation between April 2017 and May 2019. The principle of this technique is performing an extravesical cross-trigonal ureteral reimplantation with intracorporeal tailoring of the ureter.

View Article and Find Full Text PDF

[Controllable systemic destruction of old collagen fibers as a novel approach for rejuvenating biological aging in mammals.].

Adv Gerontol

November 2019

Geriatric Division of Tel-Aviv Souraski Medical Center affiliated to the Sackler School of Medicine, Tel-Aviv University, 6 Weizman str., Tel-Aviv 6423906, Israel.

Aging of extracellular proteins colloidal systems is one of major synchronizing mechanism in mammal`s «biological clock». We hypothesized that induced controllable modification of connective tissue composition could reverse aging. In murine experimental models collagenase was used for selective destruction of old collagen.

View Article and Find Full Text PDF