123 results match your criteria: "a Regional Medical Research Center RMRC ; Bhubaneswar[Affiliation]"

(L.), commonly known as carrom seeds or Ajwain, has been extensively studied for its medicinal properties. In this study, anti-mycobacterial effect of AEO in liquid and fume form was investigated against and ).

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Editorial: One Health approaches to combat infectious diseases.

Front Microbiol

November 2023

UCIBIO - Applied Molecular Biosciences Unit, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.

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Acrylamide in potato chips in Iran, health risk assessment and mitigation.

Food Addit Contam Part B Surveill

March 2024

Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

This study aimed to determine the acrylamide content in potato chips sold in Kermanshah, Iran and assess the potential health concerns associated with acrylamide exposure. HPLC-DAD was used to analyse 120 samples across 40 brands. The possible non-carcinogenic risk index for adults was below 1 for all 40 brands (100%), but for children it was only below 1 for 9 brands (22.

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Orofacial clefts (OFCs) have been linked to various toxic and essential trace elements (TETEs) worldwide. However, review estimation is absent. Therefore, addressing the hypothesis that TETEs are associated with OFCs is the main area of this review.

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Introduction: Personnel involved in essential services or residing in high-risk areas during the COVID-19 pandemic are at increased risk of getting infected. We evaluated the proportion of personnel infected in several high-risk groups in Odisha using seroprevalence studies.

Methodology: During July to November, 2020, individuals from multiple high-risk groups in 6 urban cities (Bhubaneswar, Berhampur, Cuttack, Malkangiri, Paralakhemundi, and Rourkela) in Odisha, India, were recruited to the study after obtaining written informed consent.

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Oral cancer is one of the leading causes of death worldwide, and its prevalence is especially high in developing countries. As an oral cancer treatment, traditional therapies are commonly used. Nonetheless, these treatments frequently result in a variety of side effects.

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Outbreaks of acute encephalitis syndrome (AES) with unknown aetiology are reported every year in Gorakhpur district, Uttar Pradesh, India, and Orientia tsutsugamushi, the rickettsial pathogen, responsible for scrub typhus has been attributed as the primary cause of AES problem. However, information on the prevalence of other rickettsial infections is lacking. Hence, this study was carried out to assess any occurrence of tick- and flea-borne rickettsial agents in villages reporting AES cases in this district.

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Background: With the reports of indigenous cases of dengue and chikungunya in the forest-covered rural tribal malaria-endemic villages of Dhalai District, Tripura, India, an exploratory study was undertaken to identify the vector breeding sites.

Methods: From June 2021 to August 2022, mosquito larvae were collected from both natural and artificial sources in the villages, house premises, and their nearby forested areas outside of the houses. Other than morphological characterisation, species were confirmed by polymerase chain reaction targeting both nuclear (ITS2) and mitochondrial genes (COI) followed by bidirectional Sanger sequencing.

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Article Synopsis
  • The study investigated the ACE gene's insertion/deletion (I/D) variation (rs4646994) in 108 lupus patients and 110 healthy controls in western Iran, focusing on its link to oxidative stress.
  • Results showed that the DD genotype significantly increased the risk of systemic lupus erythematosus (SLE), while the ID genotype offered a protective effect, lowering the risk compared to the II genotype.
  • SLE patients exhibited higher levels of malondialdehyde (MDA) and neopterin, along with lower paraoxonase (PON) activity compared to controls, indicating a potential relationship between oxidative stress and SLE risk associated with ACE genotypes.*
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Probiotic properties and antimicrobial evaluation of silymarin-enriched Lactobacillus bacteria isolated from traditional curd.

Sci Rep

July 2023

Department of Food Biotechnology, Branch for Northwest and West Region, Agricultural Biotechnology Research Institute of Iran, Agricultural Research, Education and Extension Organization (AREEO), Tabriz, Iran.

Article Synopsis
  • * Researchers isolated 52 strains of bacteria from traditional curd samples, identifying five with strong survival rates in tough conditions, good hydrophobicity, auto-aggregation, co-aggregation, and cholesterol removal ability.
  • * Results showed that combining silymarin with these probiotic strains significantly enhances antifungal activity against A. flavus compared to using either silymarin or the probiotics alone.
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Article Synopsis
  • India has an 8.6% tribal population, and understanding the health issues faced by high-altitude tribes is crucial for socio-economic development and health transformation.
  • A study conducted in the Lahaul and Spiti district assessed health problems over four years, using data from hospitals and health centers.
  • The findings revealed high rates of communicable diseases like respiratory infections and tuberculosis, as well as non-communicable diseases such as hypertension and diabetes, highlighting a need for targeted public health measures.
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Objectives: To highlight and assess the impact of intervention tools used by Indian Council of Medical Research (ICMR) against COVID19 associated infodemic in the world's largest democratic country, India.

Study Design: It is a retrospective cross sectional study. The impact of ICMR's multi-pronged strategy to address the infodemic during pandemic has been assessed through analysis of print media reportage and social media engagements.

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Background: The present study reports on the comprehensive analysis of Vibrio cholerae O1 and non-O1/non-O139 serogroups isolated from environmental water sources during cholera outbreaks, epidemics and surveillance studies between years 2007 to 2019 from different districts of Odisha, India.

Methods: A total of 85 stocked cultures of V. cholerae O1 and non-O1/non-O139 strains were analyzed for different ctxB genotypes, toxic genes, antibiogram profiles through PCR assays and pulsotyped by pulsed-field gel electrophoresis (PFGE).

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Article Synopsis
  • Snakebite envenoming (SBE) is a deadly issue in tropical regions, especially in India, where there's poor awareness and access to treatment, leading to high death rates.
  • The National Snakebite Project aims to improve healthcare systems in Maharashtra and Odisha by assessing current practices, providing education, and training health workers on snakebite management.
  • The project's multi-phase approach will evaluate its impact on community knowledge and healthcare efficiency, with potential benefits for other regions facing similar challenges.
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The microbiome in the female reproductive tract plays an essential role in immune modulation and reproductive health. However, various microbes become established during pregnancy, the balance of which plays a crucial role in embryonic development and healthy births. The contribution of disturbances in the microbiome profile to embryo health is poorly understood.

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Article Synopsis
  • Acute encephalitis syndrome (AES) is a significant health issue in India, primarily caused by the Japanese Encephalitis (JE) virus, particularly affecting children under 15, despite vaccination efforts.
  • A study involving 266 children in Uttar Pradesh assessed the immune response to the SA-14-14-2 JE vaccine, finding that a majority (97.74%) had no detectable anti-JEV-specific IgG antibodies after two doses.
  • Results indicated a declining trend in antibody levels over time, highlighting the need for booster doses to maintain immunity against the JE virus in vaccinated children.
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Background: Recent studies on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reveal that Omicron variant BA.1 and sub-lineages have revived the concern over resistance to antiviral drugs and vaccine-induced immunity. The present study aims to analyze the clinical profile and genome characterization of the SARS-CoV-2 variant in eastern Uttar Pradesh (UP), North India.

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Health research in the state of Odisha, India: A decadal bibliometric analysis (2011-2020).

J Family Med Prim Care

July 2022

Department of Community and Family Medicine, AIIMS Bathinda, Punjab, India.

Background: Bibliometric analyses are an important tool for evaluating health research outputs in terms of their distribution, trends, contributors, focus, and funding sources. The transition from millennium to sustainable development goals has led to a gradual shift in the health policy, and possibly, research priorities of low-income settings in the Empowered Action Group (EAG) states lagging in socioeconomic and health parameters, and also ranking low on innovations and research. In this study, we depict the recent trends, quantity, type, focus, and sources of health-related research in the EAG state of Odisha, India.

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The Malaria Evolution in South Asia (MESA) International Center for Excellence in Malaria Research (ICEMR) was established by the US National Institutes of Health (US NIH) as one of 10 malaria research centers in endemic countries. In 10 years of hospital-based and field-based work in India, the MESA-ICEMR has documented the changing epidemiology and transmission of malaria in four different parts of India. Malaria Evolution in South Asia-ICEMR activities, in collaboration with Indian partners, are carried out in the broad thematic areas of malaria case surveillance, vector biology and transmission, antimalarial resistance, pathogenesis, and host response.

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Background And Aim: Autism spectrum disorder (ASD) is a neurodevelopmental illness characterized by difficulties in social communication and repetitive behaviors. There have been many previous studies of toxic metals in ASD. Therefore, the priority of this study is to review the relationships between exposure to toxic metals and ASD.

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Prostate cancer (PCa) pathology has been linked to vitamin D, vitamin D receptors (VDRs), and vitamin D binding proteins (VDBPs). We sought to investigate the association between VDR rs2228570 and rs1544410 as well as VDBP rs7041 polymorphisms and serum 25-hydroxyvitamin D (25(OH)-vitamin D) levels in PCa patients. Blood samples were collected from 111 PCa patients and 150 age-matched healthy volunteers.

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We investigated the probiotic potential of a microencapsulated ABRIINW.N7 for control of infection in hybrid ( × ) red tilapia. A two-phase experiment approach was completed in which bacteria were propagated, from which a culture was isolated, identified using molecular techniques, and microencapsulated to produce a stable commercial fructooligosaccharide (FOS) and fenugreek (Fk) product of optimal concentration.

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Background: The healthcare infrastructure of a country determines the health-seeking behaviour of the population. In developing countries such as India, there is a great disparity in the distribution of healthcare institutions across urban and rural areas with disadvantages for people living in rural areas.

Objectives: Our objectives were to study the health-seeking behavior and factors associated with the use of formal healthcare among the Gorakhpur Health and Demographic Surveillance System (GHDSS) cohort of North India.

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