1 results match your criteria: "a Orthopaedic Department of the First Affiliated Hospital of Guangzhou Medical University[Affiliation]"
Carboxymethylcellulose with phenolic hydroxyl microcapsules enclosinggene-modified BMSCs for controlled BMP-2 release in vitro.
Artif Cells Nanomed Biotechnol
December 2017
a Orthopaedic Department of the First Affiliated Hospital of Guangzhou Medical University, Guangdong Key Laboratory of Orthopaedic Technology and Implant Materials , Guangzhou , China.
Objectives: The present study aimed to develop microparticles of phenolic hydroxyl derivative of carboxymethylcellulose (CMC-Ph) via Co-flow microfluidics technology and encapsulated gene-modified rat bone mesenchymal stem cells (BMSCs) for the detection of the growth factor release was controlled by Tet-on system. Meanwhile, we investigated the effect of the CMC-Ph microcapsules and Lentiviral transduction on osteogenesis of BMP2-BMSCs.
Methods: The middle size of CMC-Ph microcapsules was prepared by optimized co-flow microfluidics through ejecting fluid CMC-Ph suspension (mixed with HRP) into co-flowing liquid paraffin which blends HO at priority.