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Optimization of artemether-loaded NLC for intranasal delivery using central composite design.
Drug Deliv
July 2016
a J.S.S. College of Pharmacy, Department of Pharmaceutics , Rocklands , Udhagamandalam , Tamil Nadu , India.
The objective of the study was to optimize artemether-loaded nanostructured lipid carriers (ARM-NLC) for intranasal delivery using central composite design. ARM-NLC was prepared by microemulsion method with optimized formulation having particle size of 123.4 nm and zeta potential of -34.
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