2 results match your criteria: "a Clinical Biochemistry Department[Affiliation]"

Blood biomarkers in ischemic stroke: potential role and challenges in clinical practice and research.

Crit Rev Clin Lab Sci

August 2018

c Second Department of Neurology , Attikon Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens , Greece.

Fast and accurate diagnosis of stroke is crucial for the immediate application of the right therapy to patients. However, rapid diagnosis is still a challenge since an ischemic stroke cannot be identified based only on clinical assessment. CT or MRI imaging is required to rule out hemorrhagic stroke since thrombolytic therapy can lead to increased intracranial bleeding and further aggravation of hemorrhagic stroke.

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Article Synopsis
  • The study aimed to evaluate sex hormones, leptin, and insulin resistance in men with prostate cancer (PCa) and benign prostatic hyperplasia (BPH), and to explore how these hormones relate to prostate tissue scores.
  • A total of 210 men aged 45 and older were analyzed, grouped into those with PCa, those with BPH, and control subjects, with measurements of hormones like testosterone, insulin, and leptin taken across the groups.
  • Results showed that men with PCa and BPH had higher testosterone levels compared to controls, but PCa patients had notably higher leptin and estradiol levels, suggesting an altered hormonal profile associated with the pathogenesis of prostate cancer.
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