5,959 results match your criteria: "Zygomycosis"

Mucormycosis after liver transplant: Case series and literature review.

Med Mycol Case Rep

December 2024

Infectious Diseases Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Colonia Belisario Domíngeuz Sexxión XVI, Tlalpan, Mexico City, CP 4080, Mexico.

We describe two cases of possible healthcare-associated mucormycosis in liver transplant recipients. Mucorales may be acquired from environmental sources such as contaminated medical equipment, grafts or procedure related. Gastrointestinal mucormycosis is the second most common presentation in healthcare-associated infections.

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Unusual Presentation of Conidiobolomycosis.

J Assoc Physicians India

December 2024

Assistant Professor, St John's Medical College, Bengaluru, Karnataka, India, Corresponding Author.

A 31-year-old gentleman, hailing from West Bengal, a farmer by occupation, with no known prior comorbidities, presented with a history of multiple painful swellings over the abdomen, thorax (back and front), and suprapubic region of 6 months' duration. The swelling started in the abdomen and subsequently involved the thorax. It also progressively increased in size over the 6 months.

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LARYNGEAL MUCORMYCOSIS IN AN UNCONTROLLED DIABETIC PATIENT: A CASE REPORT.

J Ayub Med Coll Abbottabad

December 2024

Department of ENT, Shaikh Zayed Hospital, Lahore, Department of ENT, Ayub Medical College, Abbottabad-Pakistan.

Article Synopsis
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[Mucormycosis of the paranasal sinuses].

Orv Hetil

December 2024

2 Borsod-Abaúj-Zemplén Vármegyei Központi Kórház és Egyetemi Oktatókórház, Fül-orr-gégészeti és Fej-nyaksebészeti Osztály Miskolc Magyarország.

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Laboratory practices for the diagnosis and management of mucormycosis in France, 2024.

J Mycol Med

December 2024

Laboratoire de Parasitologie-Mycologie, Hôpital Européen Georges Pompidou, Hôpital Universitaire Necker, Unité de Parasitologie-Mycologie, Service de Microbiologie, Paris, France. Electronic address:

This study investigates the diagnostic practices for mucormycosis among 30 French University Hospital mycology laboratories, in 2024. All laboratories perform both direct examination and culture, with fluorescent brighteners being the most commonly used method for direct examination. While 77 % of the participating laboratories routinely identify Mucorales to the species level, with 70 % having adopted Mucorales-specific quantitative PCR, primarily for the diagnosis of invasive fungal infections.

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Mucormycosis is an aggressive, angioinvasive infection associated with high morbidity and mortality. The disease remains difficult to treat, with limited available antifungal drugs. Consequently, there is an urgent need to develop alternate therapeutics against mucormycosis.

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Epidemiological Trends of Mucormycosis in Europe, Comparison with Other Continents.

Mycopathologia

November 2024

Fourth Department of Internal Medicine, General University Hospital "Attikon", National and Kapodistrian University of Athens, 12462, Athens, Greece.

Article Synopsis
  • * The incidence in developed countries is relatively low (0.06 to 0.3 cases per 100,000), but in India, it spikes to about 14 cases per 100,000, making it significantly more prevalent there than in Europe, where rates range from 0.04 to 0.12.
  • * Diabetes mellitus is the most common risk factor globally for mucormycosis, with varying patterns; in Europe, hematological cancers are more prevalent, while the disease often appears in patients
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused coronavirus disease 2019 (COVID-19) has been connected to numerous opportunistic bacterial and fungal infections. Mucormycosis is a fatal opportunistic disease that became much more common with the second COVID-19 wave. We plan to look into the prognosis and course of mucormycosis following COVID-19, as well as the risk of mucormycosis in cases with COVID-19 pneumonitis.

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A clinicopathologic picture caused by Lichtheimia sp. in a 33-year-old male Sapajus xanthosternos kept in a conservationist center is described. Acute apathy, vomiting, fever, and polydipsia were associated with pneumonia, enteritis, and gastritis presenting fibrinoid vasculitis containing hyphae.

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Background: Reconstruction of maxillofacial defects is challenging due to the region's complex anatomy. During the COVID-19 era, many patients lost their maxilla and chewing efficiency as a result of Mucormycosis. In such cases, custom-designed implants offer a graftless solution for seemingly hopeless situations.

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Article Synopsis
  • Tracheobronchial mucormycosis is a serious and often fatal infection that leads to narrowing of the airways, making it hard to treat.
  • A case study involved a 37-year-old woman with a history of hyperthyroidism who developed severe airway issues after a medication caused her immune system to weaken.
  • Successful treatment included advanced therapies like venous-venous ECMO and prolonged use of antifungals, showing promising results in managing the infection.
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Article Synopsis
  • Invasive aspergillosis (IA) and mucormycosis (IM) significantly affect severely ill patients, prompting the approval of isavuconazonium sulfate for treating these fungal infections in both adults and recently in children.
  • A phase 2 study involved 31 pediatric patients across multiple countries, revealing a 54.8% overall response rate to treatment and a low 6.5% all-cause case fatality at 42 days.
  • Although 93.5% of participants experienced treatment-emergent adverse events (TEAEs), the drug was generally well tolerated, and dosing conformed to safety standards previously established in adult studies.
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Utility of intraoperative scoring system in rhino-orbital mucormycosis as a prognostic tool.

Acta Otorhinolaryngol Ital

October 2024

Department of ENT and Head & Neck Surgery, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.

Article Synopsis
  • The study aimed to evaluate an intraoperative scoring system for patients with mucormycosis to predict their postoperative outcomes, particularly mortality rates.
  • It involved 80 patients who underwent surgery, with the scoring system effectively indicating that a score over 25 was linked to a high mortality rate (86.7%).
  • The research highlighted significant factors influencing mortality, including specific anatomical involvement and certain patient medical histories, underscoring the need for thorough surgical exploration to improve prognosis.
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Introduction: Coronavirus disease 2019 (COVID-19) has been associated with secondary fungal infections such as mucormycosis. We investigated the relapse rate of mucormycosis and its risk factors.

Methodology: A prospective study was conducted on COVID-19-associated mucormycosis (CAM) patients discharged from Imam Khomeini Hospital Complex, Tehran, Iran, from July 2021 to February 2022.

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Background: Mucormycosis is a severe and fatal fungal infection in patients with coronavirus disease 2019 caused by Mucorales. Here we present a case of a 63-year-old man with coronavirus disease 2019 infection, along with rhinosinusitis mucormycosis caused by Rhizopus delemar.

Case Presentation: A 63-year-old Iranian man suffering from a coronavirus disease 2019 infection with symptoms of cough, shortness of breath, and generalized body pain.

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Digital workflows have revolutionized denture fabrication, offering greater customization and rapid production. This clinical report describes 2 treatment approaches using digital techniques to address prosthetic challenges. The first patient had a large maxillary defect after mucormycosis surgery, necessitating a combination of digital and conventional methods for obturator fabrication because of computer-aided design software program limitations.

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In addition to anatomical loss, removal of the full or portion of the orbit results in a facial deformity and psychological distress for the patient. This article details a practical case of prosthetic rehabilitation using digital workflow for an orbital deformity caused by post-COVID-19 Mucor mycosis. The main goal of this case study was to create a maxillofacial orbital prosthesis that is well-retained, simple to use, and accurate in terms of appearance.

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Potential activity of nanomaterials to combat SARS-CoV-2 and mucormycosis ‎coinfection‎.

Expert Rev Anti Infect Ther

December 2024

Department of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.

Article Synopsis
  • * There is a growing interest in the use of antifungal nanomaterials as a potential treatment alternative, as they may improve the management of COVID-19-related fungal infections like mucormycosis.
  • * Recent developments in nanomaterials offer promise, but more research is necessary to effectively utilize these therapies against mucormycosis, especially when it occurs alongside viral infections.
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Invasive fungal infection (IFI) is an important cause of morbidity and mortality in acute leukemia patients. In the past few decades, the incidence of IFI has dramatically increased. Nevertheless, the management of IFI has become more complicated owing to changes in the epidemiology of fungal diseases and therapeutic regimens.

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The COVID-19-Associated Mucormycosis with Cutaneous Involvement.

Skinmed

October 2024

Department of Dermatology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, IndiaDepartment of ENT & HNS, All India Institute of Medical Sciences, Raipur, Chhattisgarh, IndiaDepartment of Microbiology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, IndiaDepartment of Pathology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Mucormycosis is an invasive fungal infection caused by fungi of the order Mucorales. During the coronavirus disease 2019 (COVID-19), a rise in the number of COVID-19-associated mucormycosis (CAM) patients was reported globally. Cutaneous mucormycosis is the third most common presentation of mucormycosis.

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Article Synopsis
  • - The study focuses on the rise of invasive fungal sinusitis, particularly mucormycosis, in post-COVID-19 patients in India, highlighting the importance of early diagnosis through neuroimaging to improve survival rates.
  • - Researchers analyzed MR imaging from 91 confirmed cases, finding that over half of the patients (51.6%) had advanced disease with intracranial spread, with significant complications such as cavernous sinus involvement and osteomyelitis.
  • - The results showed that unlike non-COVID-19 cases, there were no instances of certain severe complications like thrombosis in the studied COVID-19-associated cases, emphasizing unique patterns in disease manifestation.
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