1,286 results match your criteria: "Zunyi Medical College[Affiliation]"

Article Synopsis
  • A clinical trial named CHANGE examined how nicorandil, a drug that may enhance blood flow and reduce heart damage, affects infarct size in heart attack patients undergoing a procedure called primary percutaneous coronary intervention.
  • The study included 238 patients who were randomly assigned to receive either nicorandil or a placebo prior to their treatment, with a focus on measuring infarct size using cardiac magnetic resonance imaging at 5 to 7 days and 6 months later.
  • Results showed that the nicorandil group had significantly smaller infarct sizes, less incidence of complications during the procedure, and better overall heart function compared to the placebo group.
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Introduction: The chronic ischemic injury of the upper/lower limbs caused by thromboangiitis obliterans (TAO, Buerger's disease) is difficult to heal, leading to high morbidity and amputation risk, seriously lowering the quality of life of patients. So far, the pathogenesis of this disease is still not clear, and there are still no effective therapeutic approaches. Here, we first use an improved bone transport technique to treat TAO-related foot ulcers and achieve good therapeutic effects.

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To determine the ultrasound imaging characteristics of patients with bronchial anthracofibrosis (BAF) and identify clinical markers for prevention and treatment. We randomly selected 1243 participants (113 with BAF) who underwent bronchoscopy and received treatment at our institution between April 2018 and October 2019. BAF was classified as flat, deep-seated retracted, or black mucosal protruding based on microscopic findings.

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Randomized Control Study on Hemoperfusion Combined with Hemodialysis versus Standard Hemodialysis: Effects on Middle-Molecular-Weight Toxins and Uremic Pruritus.

Blood Purif

August 2022

Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

Introduction: Classic hemodialysis schedules present inadequate middle-molecular-weight toxin clearance due to limitations of membrane-based separation processes. Accumulation of uremic retention solutes may result in specific symptoms (e.g.

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Chest compressions are a key component of cardiopulmonary resuscitation (CPR). The determination of the optimal compression point (OCP) in adult CPR is an indispensable critical factor for high quality chest compressions (CCs). At present, the OCP for adult CPR is still controversial, which still needs further research and discussion.

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Article Synopsis
  • Ciprofol is a new anesthetic similar to propofol but with better pharmacokinetic properties, and it was tested for safety and effectiveness in a clinical trial comparing it to propofol during gastroscopy and colonoscopy.
  • The trial involved 289 patients receiving either ciprofol (0.4 mg/kg) or propofol (1.5 mg/kg), and the success rate for completing colonoscopy was 100% for ciprofol and 99.2% for propofol.
  • Ciprofol resulted in significantly fewer adverse reactions (31.3%) and less pain during injection (4.9%) compared to propofol (62.8% and 52.4%), showing it
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Introduction And Importance: Foreign body ingestions often occur in children between the ages of six months and three years. Swallowing button battery can cause serious complications such as gastrointestinal mucosa tissue necrosis and esophageal perforation. Fatal secondary lesions after foreign body removal are rarely reported.

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Background: Evidence of the use of drug-coated balloons (DCB) in large or small coronary lesions and in-stent restenosis has accumulated over the past years. Due to their anatomical peculiarity, the treatment of very small vessels (VSV) (lumen diameter <2 mm) is still a controversial issue. Studies that examine the use of DCB in VSV are limited.

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Introduction: The staphylococcal enterotoxin C (SEC), a commercially available bio-product from (), has been widely used to control MPE.

Objectives: We designed and performed a new systematic review (SR) and meta-analysis to clarify the perfusion protocols with SEC, determine their clinical effectiveness and safety, and reveal the indication and optimum usage for achieving the desired responses.

Methodology: All randomized controlled trials (RCTs) about SEC for MPE were collected from electronic databases (from inception until July 2021), and clustered into multiple logical topics.

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Introduction: Longer follow-up was necessary to determine the exact value of mastoscopic axillary lymph node dissection (MALND).

Methods: From January 1, 2003, to December 31, 2005, 1027 patients with breast cancer were randomly assigned to two groups: MALND and CALND (conventional axillary lymph node dissection); 996 eligible patients were enrolled.

Results: The final cohort of 996 patients was followed for an average of 198 months.

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Objective: To investigate the correlation between serum levels of 25-hydroxy vitamin D [25(OH)D] and the visceral fat area of patients with type 2 diabetes mellitus (T2DM) in the context of different bone mass.

Materials And Methods: A total of 180 patients with T2DM were randomly selected for bone mineral density (BMD) examination. According to the results, they were divided into three groups: T2DM normal bone group (group A); T2DM bone mass reduction group (group B); T2DM osteoporosis group (group C).

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The intrapleural administration with thymic peptides in malignant pleural effusion: A clusteredsystematicreview and meta-analysis.

Int Immunopharmacol

June 2022

Evidence-Based Medicine Center, MOE Virtual Research Center of Evidence-based Medicine at Zunyi Medical College, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou, China; Department of General Practice, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou, China. Electronic address:

Article Synopsis
  • Thymic peptides (TPs) are utilized in the treatment of malignant pleural effusion (MPE), particularly linked to lung cancer, and this review aims to clarify their effectiveness and safety.
  • A systematic review of 34 trials revealed that the combination of thymosin and oxaliplatin significantly improves patient outcomes, including complete response rates and overall survival, especially in those with moderate to large effusions and adequate performance status.
  • The findings support the use of TPs, especially thymosin with L-OHP, as effective agents for pleurodesis in MPE, demonstrating both positive clinical responses and relatively good safety profiles.
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A case of musculi peronaeus tertius anatomic variation.

Surg Radiol Anat

March 2022

School of Traditional Chinese Medicine, Southern Medical University, No. 1838, North of Guangzhou Great Road, BaiYun District, Guangzhou, 510515, Guangdong Province, China.

In the routine dissections study for medical postgraduates, a rare anatomical variation between the right leg and the ankle was observed on the Asian male cadaver. The peronaeus tertius muscle in this cadaver's right leg divided into two tendons: the first tendon was attached to the base of the fifth metatarsal bone, and the second tendon was inserted into the base of the fourth metatarsal bone. The purpose of this paper is to provide detailed anatomical case reports, and to discuss the possible causes and mechanisms of the variation by reviewing relevant literature, so as to provide some reference for future anatomical and clinical related disease research.

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To investigate the effect of nonylphenol (NP) exposure on the colonic mucosa in rats, and the protective effects of Guizhou zinc-selenium tea (Zn-Se tea) on the damage induced by NP, sixty Sprague-Dawley rats were randomly divided into 6 groups ( = 10 in each group): control group (corn oil), and rats gavaged with NP at the doses of 0.4 mg/kg/d (Low NP group), 4 mg/kg/d (Medium NP group), 40 mg/kg/d (High NP group), and 40 mg/kg NP combined with green tea group at the doses of 0.2 g/ml (NP + GT group) and 0.

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Background: This study aimed to evaluate the differences in cervical appearance among different human papillomavirus (HPV) genotypes in patients with high-grade squamous intraepithelial lesions (HSILs).

Methods: A total of 239 histopathological HSIL patients were included and divided into eight groups on the basis of HPV genotype in this prospective study. We present a reliable imaging method that provides reproducible, sensitive and unbiased assessments of cervical appearance characteristics.

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Lung cancer with PET/CT-defined occult nodal metastasis yields favourable prognosis and benefits from adjuvant therapy: a multicentre study.

Eur J Nucl Med Mol Imaging

June 2022

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200443, China.

Purpose: To investigate the surgical prognosis and efficacy of adjuvant therapy in non-small cell lung cancer (NSCLC) with occult lymph node metastasis (ONM) defined by positron emission tomography/computed tomography (PET/CT).

Methods: A total of 3537 NSCLC patients receiving surgical resection were included in this study. The prognosis between patients with ONM and evident nodal metastasis, ONM patients with and without adjuvant therapy was compared, respectively.

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Objective: The objective was to study the relationship of serum uric acid, C-reactive protein, and N-terminal pro-B-type natriuretic peptide levels with acute cerebral infarction.

Methods: A total of 96 acute cerebral infarction patients were divided into small, middle, and large infarct size groups based on the size of infarct focus and mild, moderate, and severe infarction groups based on the evaluation criteria of nerve defect degree. In addition, 75 healthy people were selected as the control group.

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Retraction notice: Effect of educational interventions on health in childhood: a meta-analysis of randomized controlled trials [Public Health Volume 164, November 2018, Pages 134-147].

Public Health

December 2021

Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing 400014, China; Ministry of Education Key Laboratory of Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, China; Chongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory Disorders, Chongqing 400014, China. Electronic address:

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).

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This study aimed to investigate the clinicopathological features and prognosis of immunoglobulin A nephropathy (IgAN) with arterial-arteriolar sclerosis (AS). Patients with biopsy-proven IgAN from the West China Hospital of Sichuan University were retrospectively enrolled. Clinicopathological features were collected.

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Background: The relationship between acute respiratory distress syndrome (ARDS)/acute lung injury (ALI) and levels of certain inflammatory factors remains controversial. The purpose of this meta-analysis was to summarize the available studies evaluating the association between levels of inflammatory factors and ARDS/ALI incidence.

Methods: We searched the PubMed, EmBase, and Cochrane databases for studies published up to July 2017.

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Article Synopsis
  • The study investigates the epidemiological characteristics and association rules of concurrent extrapulmonary tuberculosis (EPTB) cases in China, addressing a gap in previous research that focused only on single-site EPTB.
  • Conducted from January 2011 to December 2017 on over 208,000 patients, the research found tuberculous pleurisy to be the most common lesion, and identified key association rules concerning different EPTB types based on gender and age.
  • The findings highlight the prevalence of multiple EPTB types occurring together and emphasize the need for increased awareness for timely diagnosis and treatment in clinical settings.
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Aims And Objectives: To compare the safety of replacing peripheral intravenous catheter as clinically indicated versus routine replacement on patient outcomes in the Chinese context.

Background: Some evidence from developed countries recommend replacing peripheral intravenous catheter as clinically indicated; however, there is limited evidence from developing countries.

Design: A multisite randomised controlled trial.

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Objective: To evaluate predictors of unfavorable outcome in stent-assisted coiling for symptomatic unruptured intracranial spontaneous vertebral artery dissecting aneurysms (uis-VADAs) based on 608 reconstructed lesions in 30 medical centres.

Methods: A total of 608 patients (male:female=479:129; mean age, 53.26±10.

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Recently, the effect of endocrine-disrupting chemicals on the cancer procession has been a concern. Nonylphenol (NP) is a common environmental estrogen that has been shown to enhance the proliferation of colorectal cancer (CRC) cells in our previous studies; however, the underlying mechanism remains unclear. In this study, we confirmed the increased concentration of NP in the serum of patients with CRC.

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Endocrine-disrupting chemicals (EDCs) might increase the risk of childhood diseases by disrupting hormone-mediated processes that are critical for growth and development during childhood, however, the association among the exposure level of EDCs such as Nonylphenol (NP), Bisphenol A (BPA), Dimethyl phthalate (DMP) in children and environmental risk factors, as well as hepatic function has not been elaborated. This study aimed to discuss this interesting relationship among NP, BPA, DMP concentrations in serum, environmental risk factors, hepatic function of 5- to 14-year-old children in industrial zone, residential zone and suburb in northern district of Guizhou Province, China. In Zunyi city, 1006 children participated in cross-sectional health assessments from July to August 2018, and their parents completed identical questionnaires on the environmental risk factors of EDCs exposure to mothers and children.

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