1,286 results match your criteria: "Zunyi Medical College[Affiliation]"
Front Oncol
July 2024
Department of Thoracic Oncology, Affiliated Hospital of Zunyi Medical College, Zunyi, China.
Thymic carcinoma (TC) is an uncommon type of thymic epithelial tumors. Patients with relapsed or refractory TCs have a poor prognosis. Immune checkpoint inhibitor monotherapy can be applied as a second-line treatment for such cases.
View Article and Find Full Text PDFBackground: This study aimed to assess the acceptability, feasibility, and preliminary effectiveness of a crowdsourced HIV partner services (PS) intervention among men who have sex with men living with HIV (MLWH) in China.
Methods: A pilot 2-arm randomized controlled trial was conducted in 3 HIV testing clinics in China. The control arm received conventional HIV PS, whereas the intervention arm received a crowdsourced intervention, including HIV self-testing kits for secondary distribution (HIVST-SD), digital education materials, and assisted PS.
Phytomedicine
July 2024
Department of Biological Sciences, Faculty of Health Sciences, University of Macau, Macau, PR China; Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau, PR China; Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, PR China; Proteomics, Metabolomics and Drug development core facility, Faculty of Health Sciences, University of Macau, Macau SAR, China. Electronic address:
Background: Euphorbia helioscopia L (EHL), a widely used medicinal plant in traditional Chinese medicine, has shown promising effects on certain cancers. However, previous studies on EHL did not elucidate the underlying molecular mechanisms. Herein, for the first time, we present the strong therapeutic potential of EHL extracts on malignant hemangioendothelioma, a rare type of vascular tumor.
View Article and Find Full Text PDFESC Heart Fail
April 2024
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Aims: A therapeutic strategy for chronic heart failure (HF) is to lower resting heart rate (HR). Ivabradine is a well-known HR-lowering agent, but limited prospective data exist regarding its use in Chinese patients. This study aimed to evaluate the effectiveness and safety of ivabradine in Chinese patients with chronic HF.
View Article and Find Full Text PDFCell Biochem Biophys
March 2024
Scientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China.
Excessive aggressive migration and invasion are important factors that increase the mortality of cancer patients. Matrix metalloproteinase 13 (MMP13) expression is positively correlated with lung cancer malignancy. However, the mechanism underlying an elevated MMP13 expression is not clearly defined.
View Article and Find Full Text PDFFront Physiol
October 2023
Department of Burns and Plastic Surgery, Afliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Owing to the need for liposuction and its unsuitability for allogeneic transplantation, the clinical application of stromal vascular fraction gel (SVF-gel) combined with fractional CO laser for scar treatment is limited. Adipose tissue extract (ATE), rich in cytokines and growth factors, offers a more convenient option for clinical practice as it can be easily prepared using purely physical methods and has low immunogenicity. We aimed to evaluate the effectiveness of ATE combined with fractional CO laser in the treatment of hypertrophic scars.
View Article and Find Full Text PDFBr J Cancer
November 2023
Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Jinan, China.
Background: This prospectively randomised, double-blinded, placebo-controlled, multicenter Phase 3 clinical trial was conducted to assess the efficacy and safety profile of nimotuzumab (nimo) plus concurrent chemo-radiotherapy (CCRT) in patients with unresectable locally advanced ESCC.
Methods: Patients were randomly assigned (1:1) to receive CCRT plus nimotuzumab or placebo. The primary endpoint was overall survival (OS).
Eur J Nucl Med Mol Imaging
January 2024
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Purpose: No consensus on a grading system for invasive lung adenocarcinoma had been built over a long period of time. Until October 2020, a novel grading system was proposed to quantify the whole landscape of histologic subtypes and proportions of pulmonary adenocarcinomas. This study aims to develop a deep learning grading signature (DLGS) based on positron emission tomography/computed tomography (PET/CT) to personalize surgical treatments for clinical stage I invasive lung adenocarcinoma and explore the biologic basis under its prediction.
View Article and Find Full Text PDFClin Chim Acta
September 2023
Department of Nephrology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:
Background: We investigated alterations in the serum metabolomic profile of IgA nephropathy (IgAN) patients and screen biomarkers of IgA nephropathy based on ultra-performance liquid chromatography-mass spectrometry (UPLC-MS).
Methods: Serum samples from 65 IgAN patients and 31 healthy controls were analyzed by ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). Univariate and multivariate analysis were performed to screen the differential metabolites.
Toxicology
September 2023
Department of Hygiene Toxicology, School of Public Health, Zunyi Medical College, Zunyi, Guizhou, PR China. Electronic address:
Int J Clin Pract
August 2023
Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China.
Epilepsia
October 2023
Department of Pediatrics, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Objective: Bone metabolism can be influenced by a range of factors. We selected children with self-limited epilepsy with centrotemporal spikes (SeLECTS) and lifestyles similar to those of healthy children to control for the confounding factors that may influence bone metabolism. We aimed to identify the specific effects of epilepsy and/or anti-seizure medications (ASMs) on bone metabolism.
View Article and Find Full Text PDFPhytomedicine
July 2023
Department of General Practice, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou, China; Evidence-Based Medicine Center, MOE Virtual Research Center of Evidence-based Medicine at Zunyi Medical College, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou, China. Electronic address:
Introduction: Aidi injection (Aidi), a traditional Chinese medicine injection, is often practiced to control malignant pleural effusion (MPE).
Objectives: We performed a registered systematic review and meta-analysis (PROSPERO: CRD42022337611) to clarify the clinical role of Aidi in MPE, reveal optimal combinations of Aidi and chemical agents, their indications, therapeutic route and usage, and demonstrate their clinical effectiveness and safety.
Methodology: All randomized controlled trials (RCTs) about Aidi in controlling MPE were collected from Chinese and English databases (up to October 2022).
Scand J Gastroenterol
November 2023
Department of Gastroenterology and Hepatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Cryobiology
June 2023
School of Stomatology, Southwest Medical University, Luzhou, 646000, China; Department of Stomatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China. Electronic address:
This study focused on the biomechanical properties and microstructural changes in dentin of teeth in different age groups after cryopreserved for different durations. Ninety third molars from three age groups (youth group, middle-age group, and elderly group), were collected and randomly divided into three groups according to freezing time at -196 °C (7 days, 30 days, and 90 days). Control group was shored at ordinary temperature.
View Article and Find Full Text PDFNeuroscience
October 2023
Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. Electronic address:
Understanding the biological basis of cognitive differences between individuals is the goal in human intelligence research. The surface area of the cortex is considered to be a key determinant of human intelligence. Adolescence is a period of development characterized by physiological, emotional, behavioral, and psychosocial changes, which is related to the recombination and optimization of the cerebral cortex, and cognitive ability changes significantly in children and adolescents.
View Article and Find Full Text PDFFront Nutr
March 2023
Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: Selenium is an essential nutrient and trace element required for human health and plays an important role in antioxidative and anti-inflammatory processes. However, the long-term impact of selenium levels on the health of patients with chronic kidney disease remains unclear.
Method: Participants in this study were 3,063 CKD adults from the Third National Health and Nutrition Examination Survey (NHANES 1999-2000, 2003-2004, and 2011-2018).
Chin Med J (Engl)
December 2023
Department of Anesthesiology and Translational Neuroscience Center, West China Second University Hospital of Sichuan University, Chengdu, Sichuan 610041, China.
Background: Red-cell transfusion is critical for surgery during the peri-operative period; however, the transfusion threshold remains controversial mainly owing to the diversity among patients. The patient's medical status should be evaluated before making a transfusion decision. Herein, we developed an individualized transfusion strategy using the West-China-Liu's Score based on the physiology of oxygen delivery/consumption balance and designed an open-label, multicenter, randomized clinical trial to verify whether it reduced red cell requirement as compared with that associated with restrictive and liberal strategies safely and effectively, providing valid evidence for peri-operative transfusion.
View Article and Find Full Text PDFZhonghua Wei Zhong Bing Ji Jiu Yi Xue
January 2023
Department of Respiratory and Critical Care Medicine, the Fifth Affiliated (Zhuhai) Hospital of Zunyi Medical College, Zhuhai 519100, Guangdong, China. Corresponding author: Wang Hongman, Email:
Acute respiratory distress syndrome (ARDS) refers to acute diffuse lung injury caused by a variety of intrapulmonary and/or extrapulmonary factors such as infection and trauma. Uncontrolled inflammatory response is the main pathological feature. Different functional states of alveolar macrophages have different effects on inflammatory response.
View Article and Find Full Text PDFSignal Transduct Target Ther
February 2023
Center of Interventional Radiology & Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, 210009, China.
Biochimie
January 2023
Department of Neurosurgery, The First People's Hospital of Zunyi, Department of Neurosurgery, ZunYi, 563000, China.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).
View Article and Find Full Text PDFMater Today Bio
February 2023
Department of Orthopaedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Intervertebral disc degeneration (IDD)-induced low back pain significantly influences the quality of life, placing a burden on public health systems worldwide. Currently available therapeutic strategies, such as conservative or operative treatment, cannot effectively restore intervertebral disc (IVD) function. Decellularized matrix (DCM) is a tissue-engineered biomaterial fabricated using physical, chemical, and enzymatic technologies to eliminate cells and antigens.
View Article and Find Full Text PDFCNS Drugs
December 2022
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Anal Chem
October 2022
The State Key Lab of Silkworm Genome Biology, College of Pharmaceutical Sciences, Southwest University, Chongqing400715, China.
Ni single-atom catalysts (SACs) were synthesized by high-temperature calcination of nickel ions and 1,10-phenanthroline on carbon black as a carrier. Benefiting from the ultrahigh atom utilization efficiency, Ni SACs can significantly accelerate decay of dissolved oxygen to generate abundant reactive oxygen species through an oxygen reduction reaction occurring on cathodes. The generated reactive oxygen species can vastly enhance the electrochemiluminescent (ECL) signal of luminol without participation of exogenous co-reactants.
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