Relevance of Anthocyanin Metabolites Generated During Digestion on Bioactivity Attributed to Intact Anthocyanins.

Epidemiological and in vitro studies suggest that dietary anthocyanins in their intact form exert beneficial effects on human health. However, the potential contributions of anthocyanin metabolites to these beneficial effects have been underestimated. The objective of this review was to critically analyze the outcomes of studies concerning the formation, identification, cellular transport, and biological actions of anthocyanin metabolites generated during digestion to formulate several premises supporting the idea that these compounds largely contribute to human health.

Assessment of watershed health, integrating environmental, social, and climate change criteria into a fuzzy logic framework.

Spatio-temporal analyses of environmental and social criteria in the context of climate change, facilitate understanding of how historical and current conditions have influenced watershed health. Previous studies have analyzed watershed health, but very few have integrated fuzzy logic with the CRITIC method (Criteria Importance Through Intercriteria Correlation), which enables us to explore alternatives to improve watershed performance. The objective of this study was to evaluate changes in watershed health through historical and projected climate change scenario in the tropical Santa Cruz watershed in Aquismón, S.

Impacts of acid mine drainage remediation in the largest gold mine of Latin America on natural water bodies in the Dominican Republic.

Impacts of the acid mine drainage (AMD) remediation are investigated on the largest gold mine in Latin America, located in the Dominican Republic. Geochemical analysis of suspended matter in water performed in 2022 on water bodies located downstream to the mine, namely, the Margajita River and Lake Hatillo, are compared with analyses made in 2007, before the AMD remediation. The results for the Margajita River show a strong decrease in heavy metal and metalloid concentrations in the dissolved phase for Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Cd, Sb, and Pb (between 89.

Experimental dataset of masonry prisms with hollow concrete blocks.

The uniaxial compressive strength is a main parameter to be considered in design of masonry structures, particularly due to gravitational loads. This dataset collection comprises test on various masonry prisms made of hollow concrete blocks. These prisms are divided into three groups: prisms consisting of 2, 3, and 4 courses, respectively.

Effectiveness in root canal disinfection and biocompatibility of a final in vitro irrigation protocol based on cellulases and a hyperosmotic solution.

Objective: To evaluate the antimicrobial capacity and cell viability of a final irrigation protocol based on the use of a hydrolases enzymes mixture (HEM) and a hyperosmotic solution (HS) as an alternative to conventional protocols.

Methods: Root canals from 28 human first molars were used to develop multispecies anaerobic biofilms in standard reactors and irrigated with various protocols according to the following groups. Group A: control (sterile saline), group B: 2.

Land surface temperature and socioeconomic residential segregation in the Metropolitan Zone of San Luis Potosí, Mexico.

Economic growth and urban sprawl in territorial systems produce an uneven distribution of infrastructure and services. This creates residential areas with high capital gains that are affordable only for the middle and upper classes. For lower-income groups, the only options are depressed urban areas with limited infrastructure.

Cultivable bacteria contribute to the removal of diclofenac and naproxen mix in a constructed wetland with Typha latifolia.

Constructed wetlands are used to remove diclofenac and naproxen from wastewater. However, the role of plants and their root-associated bacteria in removing these pharmaceuticals is still unknown. In this work, bacteria were isolated from the roots of Typha latifolia cultivated in a constructed wetland to treat a diclofenac and naproxen mix.

Invasive Candidiasis: A Promising Approach Using Jatropha Dioica Extracts and Nanotechnology.

Candida albicans, a common fungal organism, often lives harmlessly in the human body. However, under certain conditions, it can turn into a dangerous pathogen, causing infections that range from mild to life-threatening. With rising resistance to antifungal treatments, understanding and controlling this opportunistic fungus has never been more crucial.

Dual Loading of Trans-Cinnamaldehyde and Either Paclitaxel or Curcumin in Chitosan Nanoparticles: Physicochemical Characterization and Biological Evaluation Against MDCK and HeLa Cells.

Biopolymer chitosan sub-micron particles (CSMPs) were prepared by the ionic gelation technique crosslinked with sodium tripolyphosphate co-loaded with trans-cinnamaldehyde (TCIN), and either curcumin (CUR) or paclitaxel (PTX). The size of the spherical CSMPs increased from 118 nm to 136 nm and 170 nm after the loading of TCIN and CUR, whereas the loading of PTX led to a slight decrease (114 nm). Polydispersity indexes of all the samples were smaller than 0.

Fundamentals of Nonparametric Statistical Tests for Dental Clinical Research.

This article provides the foundation for employing nonparametric testing in dental clinical research. To make wise judgments in their research, investigators should learn more about the main nonparametric tests and their particular uses. Biostatistical analysis is essential in dental research; dental research frequently deviates from the assumptions that underpin traditional parametric statistics.

Towards Characterization of Hass Avocado Peel and Pulp Proteome during Postharvest Shelf Life.

In recent years, avocados have gained worldwide popularity as a nutritive food. This trend is causing a rise in the production of this fruit, which is accompanied by several problems associated with monocultural practices. Despite massive economic gains, limited molecular and structural information has been generated about avocado ripening.

Extraction of bio-hydroxyapatite from devilfish (Loricariidae) for the fluoride and cadmium adsorption from water and its feasible photocatalytic properties.

In this study, the adsorption capacity of bio-hydroxyapatite (Bio-HAp) from devilfish for the removal of F and Cd(II) from aqueous solutions was investigated. This material was synthesized according to a 2FI factorial experimental design by varying the extraction conditions for Bio-HAp, including the type of pretreatment (alkaline and peroxide), the calcination temperature from 550 to 850 °C, and the sonication process. The maximum adsorption capacities were 8.

Ursolic acid interaction with transcription factors BRAF, V600E, and V600K: a computational approach towards new potential melanoma treatments.

Context: Melanoma is one of the cancers with the highest mortality rate for its ability to metastasize. Several targets have undergone investigation for the development of drugs against this pathology. One of the main targets is the kinase BRAF (RAF, rapidly accelerated fibrosarcoma).

The Push-Out Bond Strength, Surface Roughness, and Antimicrobial Properties of Endodontic Bioceramic Sealers Supplemented with Silver Nanoparticles.

This study evaluated push-out bond test (POBT), surface roughness, and antimicrobial properties against of bioceramic sealers supplemented with silver nanoparticles (AgNPs). The sealers tested were CeraSeal, EndoSequence BC Sealer, and Bio-C Sealer. The POBT was measured with a Universal Testing Machine, and the type of failure was evaluated with a stereomicroscope.

The Biology, Impact, and Management of Beetles: A Comprehensive Review.

beetles, a diverse group of ambrosia beetles, present challenges to forestry and agriculture due to their damaging burrowing behavior and symbiotic relationships with fungi. This review synthesizes current knowledge on the biology, ecology, and management of . We explore the beetles' life cycle, reproductive strategies, habitat preferences, and feeding habits, emphasizing their ecological and economic impacts.

Pressurized liquid extraction of oak leaf polyphenols: Solvent selection via Hansen parameters, antioxidant evaluation and monoamine-oxidase-a inhibition analysis.

This study focuses on the extraction of bioactive compounds from Quercus sideroxyla Bonpl., leaves which have been shown to possess health benefits. The extraction process was done using pressurized liquid extraction (PLE), which is efficient and preserves heat-sensitive compounds.

Women's experiences in institutional childbirth care in times of the first and second waves of COVID in Mexico.

This is a qualitative study that explores the perspectives and experiences of a group of Mexican women who experienced institutionalized childbirth care in the first and second waves of the COVID-19 pandemic. Through a semi-structured script, nine women who experienced childbirth care were interviewed between March and October 2020 in public and private hospitals in the city of San Luis Potosí, Mexico. Under the Grounded Theory analysis proposal, it was identified that the health strategies implemented during the pandemic brought with them a setback in the guarantee of humanized childbirth.

Synthesis and Characterization of Thiolated Nanoparticles Based on Poly (Acrylic Acid) and Algal Cell Wall Biopolymers for the Delivery of the Receptor Binding Domain from SARS-CoV-2.

The COVID-19 pandemic required great efforts to develop efficient vaccines in a short period of time. However, innovative vaccines against SARS-CoV-2 virus are needed to achieve broad immune protection against variants of concern. Polymeric-based particles can lead to innovative vaccines, serving as stable, safe and immunostimulatory antigen delivery systems.

Revisiting Epigenetics Fundamentals and Its Biomedical Implications.

In light of the post-genomic era, epigenetics brings about an opportunity to better understand how the molecular machinery works and is led by a complex dynamic set of mechanisms, often intricate and complementary in many aspects. In particular, epigenetics links developmental biology and genetics, as well as many other areas of knowledge. The present work highlights substantial scopes and relevant discoveries related to the development of the term from its first notions.

Obesity/overweight and dental caries experience in children and adolescents: an umbrella review.

Purpose: The present umbrella review aimed to synthesize and critically assess the methodological and reporting quality of previous systematic reviews about the potential relationship between obesity or overweight and caries dental experience in pediatric patients.

Method: Electronic database and manual searches were conducted in PubMed, Embase, and Cochrane Library up to July 2023. The risk of bias assessment of eligible systematic reviews was performed using the Risk Of Bias In Systematic reviews (ROBIS) tool.

Mediation effect of body mass index on the association between serum magnesium level and insulin resistance in children from Mexico City.

Background/objectives: Reduced serum magnesium (Mg) levels have been associated with obesity, insulin resistance (IR), type 2 diabetes, and metabolic syndrome in adults. However, in the children population, the evidence is still limited. In this cross-sectional study, we aimed to analyze the association of serum Mg levels with the frequency of overweight and obesity and cardiometabolic traits in 189 schoolchildren (91 girls and 98 boys) between 6 and 12 years old from Mexico City.

Clinical Significance of the Lipid Profile Ratios and Triglyceride Glucose Index in the Diagnosis of Metabolic Syndrome.

Metabolic syndrome (MetS) is a pathophysiological condition defined by a set of metabolic alterations such as hypertriglyceridemia, hyperglycemia, hypertension, low HDL-c levels, and visceral obesity. Its presence identifies people with an increased risk of developing cardiovascular diseases and type 2 diabetes; however, the lack of practical and reliable methods for its diagnosis limits the identification of people with this condition. In this sense, the objective of this study was to analyze the diagnostic utility of markers derived from the lipid profile [triglyceride-glucose (TyG) index and the ratios total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-c), triglyceride (TG)/HDL-c, low-density lipoprotein cholesterol/HDL-c, fasting blood glucose (FBG)/HDL-c, and white blood cell/HDL-c] in the determination of MetS.

Antimicrobial and Cytotoxic Effect of Positively Charged Nanosilver-Coated Silk Sutures.

Sutures are a crucial component of surgical procedures, serving to close and stabilize wound margins to promote healing. However, microbial contamination of sutures can increase the risk of surgical site infections (SSI) due to colonization by pathogens. This study aimed to tackle SSI by synthesizing positively charged silver nanoparticles (P-AgNPs) and using them to produce antimicrobial sutures.