3 results match your criteria: "Zibo Ninth People's Hospital[Affiliation]"
Investigating the Underlying Molecular Mechanisms of Yunke on Bone Metastases from Prostate Cancer.
Biologics
July 2024
Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Objective: To explore analgesic effect and bone repair mechanism of non-radioactive technetium-99 conjugated with methylene diphosphonate (Tc-MDP, brand name, Yunke) on bone metastases (BM).
Procedures: In vivo experiment, mouse BM models of prostate cancer RM-1 cell were constructed and divided into Control, Yunke, Tc+SnCl and MDP groups based on medicine composition. Tumor specimens were inspected for size, X-ray, microCT and histopathology.
Hydroxysafflor yellow A attenuates allergic response of ovalbumin induced allergic rhinitis via Nrf2/HO-1 and inflammatory signaling pathways.
Environ Toxicol
July 2023
Department of Otorhinolaryngology, Zibo Ninth People's Hospital, Zibo, China.
Allergic reaction is the most common nasal conditions worldwide and it will remain throughout life. The symptoms of an allergic reaction include sneezing, itching, hives, swelling, difficulty breathing, and a runny nose. Hydroxysafflor yellow A (HYA) is a flavonoid compound which is the active phyto-constituent of flower of Carthamus tinctorius L.
View Article and Find Full Text PDFMicroRNA-223 Attenuates Stretch-Injury-Induced Apoptosis in Brain Microvascular Endothelial Cells by Regulating RhoB Expression.
Brain Sci
August 2022
Department of Neurosurgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Article Synopsis
- MiR-223 is a microRNA that has been shown to be over-expressed in brain tissue following traumatic brain injury (TBI) and plays a significant role in apoptosis and inflammation.
- This study investigated the effects of miR-223 on brain microvascular endothelial cells (BMECs) after stretch injury (SI), revealing that overexpression of miR-223 helps prevent damage, while blocking it worsens the situation.
- The research found that miR-223 reduces apoptosis in BMECs by decreasing levels of specific proteins like cleaved caspase-3 and RhoB, suggesting it helps maintain blood-brain barrier (BBB) integrity during TBI.