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Background: The aim of this study was to explore the function and mechanism of GKN1 in gastric cancer (GC) progression.

Methods: Firstly, we used GEO2R to perform differential gene analysis on GSE26942 and GSE79973 and constructed the protein-protein interaction network of differential genes by STRING. Next, the cytoHubba, Mcode plugins, and GEPIA were used to obtain our follow-up research object GKN1.

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