[Histo- and ultrahisto-pathology of the anterior chamber angle in congenital glaucoma].

92 trabeculectomy specimens of congenital glaucoma, aged 35 days to 46 years, were studied by light and transmission electron microscopy, with findings of narrowed anterior chamber angle, thickened ciliary muscle displaced forward, and crooked or thickened trabeculae, many disintegrated with hyaloid degeneration. The cribriform meshwork appeared dense, with deposition of fibrillae and collagen or basement membrane-like material; Schlemm's canal was absent in 3 specimens; in some the lumen was narrowed or locally obliterated; and Descemet membrane-like substance covered the trabecular meshwork. The types of pathological changes, their relationship with the symptoms, and the locations of outflow resistance were discussed.

[Ocular histopathology and ultrastructure in mucopolysaccharidosis-I].

The ocular histopathology of type I mucopolysaccharidosis was studied with histochemical, ultrahistochemical, and ultrastructural techniques. The latter method showed extensive intracellular accumulation of fibrillogranular vacuoles in virtually every ocular tissue. Ultra-histochemistry proved that the fibrillogranular material was acid mucopolysaccharide.

Contrast sensitivity in amblyopia.

Contrast sensitivity function (CSF) for sinusoid gratings of varying spatial frequencies was determined for each eye of 21 cases with unilateral amblyopia. The CSF of all amblyopic eyes, except one, showed reduced sensitivity when compared with the non-amblyopic eye of the same person. The curve showed reduction more significantly at middle and high spatial frequencies.

Retinitis pigmentosa associated with glaucoma--clinical analysis.

A clinical analysis of Retinitis Pigmentosa (RP) was made in 2,789 eyes of 1,400 patients seen over a 5 year period (1983-1987), 64 eyes of 32 cases (2.3%) of RP associated with glaucoma were investigated. Of these 32 cases, the angle closure glaucoma was much more than the open angle glaucoma (30/2).