[Genes and signaling pathways related to the biochemical recurrence of prostate cancer: An analysis based on the GEO database].

Objective: To search for the potential genes associated with the recurrence of prostate cancer (PCa) after radical prostatectomy so as to improve the prognosis of the patient.

Methods: The GSE25136 microarray dataset was downloaded from the Gene Expression Omnibus (GEO), involving 39 recurrent and 40 non-recurrent PCa samples. Differentially expressed genes were identified with the Limma package and screened by hierarchical cluster analysis using the Pheatmap package.

[Modified sandwich urethral reconstruction in laparoscopic radical prostatectomy improves early recovery of urinary continence].

Objective: To explore the safety of modified sandwich urethral reconstruction (MSUR) in laparoscopic radical prostatectomy (LRP) and its effect on the early recovery of urinary continence.

Methods: We retrospectively analyzed the clinical data on 20 patients treated by LRP with MSUR (the MSUR group) and another 21 cases of LRP without MSUR (the conventional control group) from January 2018 to September 2019. We compared the two groups of patients in the general data, anastomosis time, operation time and urinary continence recovery.

[Establishment of rat model of post-stroke depression and the effects of citalopram on behavior thereof].

Objective: To establish an animal model of post-stroke depression (PSD) and assess the effects of citalopram on PSD.

Methods: Fifty-two male SD rats were randomly divided into 3 groups. Normal group (n = 6) underwent sham operation.