6 results match your criteria: "Zhong-kai University of Agriculture and Engineering[Affiliation]"
Structural basis for the evolution and antibody evasion of SARS-CoV-2 BA.2.86 and JN.1 subvariants.
Nat Commun
September 2024
Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong Province, China.
The Omicron subvariants of SARS-CoV-2, especially for BA.2.86 and JN.
View Article and Find Full Text PDFNovel goose parvovirus VP1 targets IRF7 protein to block the type I interferon upstream signaling pathway.
Poult Sci
September 2024
Zhong Kai University of Agriculture and Engineering, College of Animal Science and Technology, Guangdong Guangzhou, 510225, China. Electronic address:
Article Synopsis
- SBDS outbreaks caused by NGPV have been noted in China since 2015, with NGPV being a single-stranded DNA virus likely transmitted vertically.
- The study found that NGPV boosts cGAS mRNA expression but weakens the induction of IFN-β, inhibiting downstream interferon-stimulated genes and interfering with the immune response.
- VP1, a viral protein, plays a crucial role in inhibiting IFN-β expression, while its truncated forms lack this capability, indicating that NGPV impacts the host's innate immune response through modulation involving IRF7.
Age-related changes in the mitochondrial, synthesis of steroids, and cellular homeostasis of the chicken ovary.
Anim Reprod Sci
August 2024
College of Animal Science & Technology, Zhong Kai University of Agriculture and Engineering, Guangzhou 510225, China; Guangdong Provincial Waterfowl Health Breeding Engineering Center, Guangzhou 510225, China. Electronic address:
In poultry reproduction, the decline of ovarian function due to aging is related to dysfunction of mitochondria exacerbated by a reduction in antioxidant capacity, ultimately leading to follicle atresia and decreased egg production. However, the mechanisms of mitochondrial dysfunction in the chicken ovary in aging have remained to be understood. Hence, this study aims to investigate the effects of aging on mitochondrial function and cellular homeostasis.
View Article and Find Full Text PDFIdentification and health risk evaluation of soil contaminated by polycyclic aromatic hydrocarbons at shale gas extraction sites based on positive matrix factorization.
Chemosphere
May 2024
College of Resource and Environment, Zhong-kai University of Agriculture and Engineering, Guangzhou 510225, China. Electronic address:
The impact of shale gas extraction on surrounding environmental media remains unclear. In this study, the current state of contamination by polycyclic aromatic hydrocarbons (PAHs), which are high-frequency contaminants of shale gas, was investigated in the soil surrounding emerging shale gas development sites. The source analysis of PAHs was conducted in the soils of shale gas extraction sites using positive matrix factorization (PMF).
View Article and Find Full Text PDFHeat enhances the inhibitory effect of lipopolysaccharide on duck granulosa cell proliferation and steroid biosynthesis in vitro.
Anim Sci J
July 2023
College of Animal Science & Technology, Zhong kai University of Agriculture and Engineering, Guangzhou, China.
Article Synopsis
- * High concentrations of LPS downregulate specific genes related to cell proliferation and steroid hormone synthesis, while also increasing p27kip1 expression, indicating cell cycle alterations.
- * Elevated temperatures further worsen LPS's inhibitory effects on gene expression related to proliferation and steroid hormone production, highlighting a complex interaction between heat and LPS in duck GCs.
Article Synopsis
- Granulosa cells (GCs) are crucial for follicle development, and this study examines how heat stress at 41°C and 43°C affects their growth and steroid production in ducks.
- Using RNA sequencing, the research identified changes in gene expression, revealing that heat stress leads to an increase in GCs blocked in the G1 phase and a decrease in genes important for follicle progression.
- A total of 241 differentially expressed genes were found, with key findings including the activation of heat shock proteins and CXC chemokines, and downregulation of collagenases, suggesting potential molecular mechanisms for reduced egg production in ducks during heat stress.