5 results match your criteria: "Zhengzhou University Fuwai Central China Cardiovascular Hospital[Affiliation]"

Article Synopsis
  • Myocardial ischemia-reperfusion injury (MI/RI) affects patients with acute myocardial infarction (AMI) and is worsened by NLRP3-mediated necrosis; exercise is an effective method for preventing and treating cardiovascular diseases.
  • The study aimed to examine how exercise preconditioning protects the heart and how it modulates NLRP3 to improve conditions after ischemia and reperfusion.
  • Results showed that moderate-intensity aerobic exercise improved heart function, reduced injury and inflammation in the heart tissue of mice, and lowered NLRP3 expression and related inflammatory proteins, indicating protective effects against MI/RI.
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Article Synopsis
  • Chest radiography is vital for diagnosing lung diseases, but errors and a shortage of skilled practitioners can lead to treatment delays.
  • This study created an advanced AI tool using a convolutional neural network (CNN) capable of accurately identifying 26 different thoracic conditions from a large dataset of over 795,000 chest X-rays.
  • The AI demonstrated impressive diagnostic accuracy, outperforming human radiologists, and is now available as web-based software to enhance chest radiograph interpretation in clinical practice.
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Development of a nomogram to predict 30-day mortality in patients with post-infarction ventricular septal rupture.

Sci Rep

July 2024

Department of Cardiology, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China.

Ventricular septal rupture (VSR) is a mechanical complication of acute myocardial infarction (AMI), and its mortality has not decreased significantly in recent decades. However, no clinical model has been developed to predict short-term mortality in patients with post-infarction VSR (PIVSR). This study aimed to develop a nomogram to predict the 30-day mortality by using the clinical characteristics of hospitalized patients with PIVSR.

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Intrinsic brain activity alterations in patients with Parkinson's disease.

Neurosci Lett

July 2023

Department of Medical Imaging, Zhengzhou University People's Hospital & Henan Provincial People's Hospital, Zhengzhou, China; Laboratory of Brain Science and Brain-Like Intelligence Technology, Institute for Integrated Medical Science and Engineering, Henan Academy of Sciences, Zhengzhou, China. Electronic address:

Objective: The objective of this study is to explore the brain activity alterations in Parkinson's disease (PD) from the perspectives of neuronal activity, synchronization of neuronal activity, and coordination of whole-brain activity.

Methods: In this study, we recruited 38 PD patients and 35 matched healthy controls (HCs). We explored intrinsic brain activity alterations in PD by comparing resting-state functional magnetic resonance imaging (rs-fMRI) metrics of the amplitude of low-frequency of fluctuation (ALFF), the fractional amplitude of low-frequency fluctuation (fALFF), percent amplitude of fluctuation (PerAF), regional homogeneity (ReHo), and degree centrality (DC).

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Association of lymphopenia and RDW elevation with risk of mortality in acute aortic dissection.

PLoS One

March 2023

Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Objective: The study aimed to investigate whether lymphopenia and red blood cell distribution width (RDW) elevation are associated with an increased risk of mortality in acute aortic dissection (AAD).

Methods: This multicenter retrospective cohort study enrolled patients diagnosed with AAD by aortic computed tomographic angiography (CTA) from 2010 to 2021 in five teaching hospitals in central-western China. Cox proportional hazards regression and Kaplan-Meier curves were used in univariable and multivariable models.

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