Tomato sucrose synthase SUS3 is involved in flower and seed development.

Sucrose is a vital product of photosynthesis and plays important roles in plant growth and development. Sucrose synthase (SUS) is one of the major contributors in sucrose utilization. However, its roles in plant development are still not well understood.

Enhanced tetracycline degradation through electron transfer activated by Bacillus cereus synthesized bio-FeS nanoparticles.

The synthesis of bio-FeS nanoparticles (NPs) was generally using Gram-negative bacteria and mostly in anaerobic systems, thus limiting their application in the degradation of toxic wastewater. In this study, we successfully synthesized bio-FeS NPs for the first time using the resilient Gram-positive bacterium Bacillus cereus, with the objective of investigating the mechanism of promoting electron transfer in the aerobic/anaerobic degradation of tetracycline (TC). The degradation efficiency of TC was increased by 2.

PpSPL1 and PpSPL15 inhibit peach branching by increasing strigolactone synthesis.

PpSPL1 and PpSPL15 inhibit peach branching by directly binding to and upregulating the expression of strigolactone (SL) synthesis gene PpLBO1. Branch number is a crucial agronomic trait that influences tree architecture, directly affecting fruit yield and quality. It remains unknown whether SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL), an important transcription factor in determining plant architecture, is involved in the peach branching process.

Evaluating fusion models for predicting occult lymph node metastasis in tongue squamous cell carcinoma.

Objectives: This study evaluated and compared the effectiveness of various predictive models for forecasting occult lymph node metastasis (LNM) in tongue squamous cell carcinoma (TSCC) patients.

Methods: In this retrospective diagnostic experiment, 268 patients were recruited from three medical centers. Based on the different hospitals from which the patients were recruited, they were divided into a training set, an internal testing set, and two external testing sets, comprising 107, 53, 63, and 45 patients, respectively.

"Pulsed" Chain Transfer Anionic Polymerization: A Green and Cost-Effective Approach for Controlled Polymer Synthesis.

Herein, we report a method that significantly enhances the atom economy of catalysts in living polymerization. By introducing intermittent, switchable chain-transfer reactions during the polymerization process, multiple regenerations of the catalyst are achieved while preserving the "living"/controlled characteristics. The specially designed catalytic system, composed of 1,2-dipyrrolidinoethane/n-butyllithium/n-butylpotassium/toluene, exhibits a chain-transfer rate that is highly sensitive to temperature.

Gasotransmitter-Nanodonor for Spatial Regulation of Anxiety-Like Behavior and Bone Metastasis.

Anxiety is highly prevalent among cancer patients, significantly impacting their prognosis. Current cancer therapies typically lack anxiolytic properties and may even exacerbate anxiety. Here, a gasotransmitter-nanodonors (GND) system is presented that exerts dual anxiolytic and anti-tumor effects via a "tumor-brain axis" strategy.

Dynamic Tumor in Situ Fluid Circulating Tumor DNA Postsurgery Effectively Predicts Recurrence and Clinical Benefits for Glioblastomas.

Background And Objectives: Glioblastoma (GBM) recurrence after surgery remains a significant clinical challenge because of limited early detection methods and effective molecular markers. This study investigates the potential of dynamic tumor in situ fluid circulating tumor DNA (TISF-ctDNA) as a tool for monitoring molecular residual disease and evaluating treatment efficacy in postsurgical patients with GBM.

Methods: In this prospective cohort study, 75 resectable glioma patients were enrolled between October 2019 to June 2023.

Latent profile analysis of anxiety and related factors among stroke patients' spouses.

To explore the potential classification of anxiety symptoms in stroke patients' spouses and analyze the characteristics of each category. From November 2019 to August 2020, a total of 224 stroke patients in the department of neurology of a tertiary hospital in Henan Province, and 224 spouse caregivers were conveniently selected. The general information questionnaire, Generalized Anxiety Disorder 7-item, the Patient Health Questionnaire 9-item scale, and modified Rankin Scale was used to assess patient and caregiver general information, anxiety, depression and patient prognosis, respectively.

3D Printed Low-Tortuosity and Ultra-Thick Hierarchical Porous Electrodes for High-Performance Wearable Quasi-Solid-State Zn-VOH Batteries.

Rechargeable aqueous Zn-ion batteries have received considerable attention in energy storage systems owing to their merits of high safety, low cost, and excellent rate performance. However, the unsatisfactory areal energy density and poor cycling performance hinder their practical applications. Herein, the VO·6HO (VOH) nanosheet arrays and Zn nanoflake arrays growing on the 3D-printed reduced graphene oxide/carbon nanotubes (3DP-rGO/CNTs) microlattices employing the electrodeposition technique, and further serve as the cathode and anode for 3D-printed aqueous Zn-VOH battery, respectively.

Chinese Position Paper on Biologic Therapy for Chronic Rhinosinusitis With Nasal Polyps.

Emerging biologics that selectively target key cytokines present a promising therapeutic alternative for patients suffering from severe, uncontrollable chronic rhinosinusitis with nasal polyps (CRSwNP). Despite the limited availability of registered biologics for CRSwNP treatment in China, the country is experiencing rapid development in this field. It is imperative to standardize the application of biologic agents in CRSwNP management in preparation for their future integration into the CRSwNP care pathway.

Research on optimal allocation of water and land resources in the Yiluo River Basin, China.

The allocation of water and land resources (WLRs) has adhered to a system where they "serve as boundaries for each other," posing challenges in satisfying the exacting management requirements for these resources in the contemporary era. In line with precise predictions of the future WLRs, the optimal allocation framework of WLRs was constructed to obtain the rational configuration scheme. The prediction results showed that the imbalance between supply and demand of WLRs will intensify in the Yiluo River Basin.

Reinforcement and MAO-A inhibition in heated tobacco products: flavor and brand variations.

Objective: This study investigates the reinforcing effects and monoamine oxidase-A (MAO-A) inhibitory properties of heated tobacco products (HTPs), comparing them to nicotine alone. It also examines brand-specific differences in MAO-A inhibition to provide a deeper understanding of the role of non-nicotine constituents in HTP use.

Methods: A rat self-administration model was used to evaluate the reinforcement patterns of HTP-T (tobacco flavor), HTP-M (menthol flavor), and nicotine under fixed-ratio schedules.

VvARF19 represses VvLBD13-mediated cell wall degradation to delay softening of grape berries.

Fruit softening directly impacts its storage life, transportability, and customer acceptance. Auxin plays a key role during fruit ripening, but the underlying mechanisms of how auxin regulates fruit softening remain unclear. In this study, we investigated the regulatory roles of auxin on berry cell wall degradation during grape ( L.

The association between features of epicardial adipose tissue and the risks of early recurrence after catheter ablation in patients with atrial fibrillation.

Background: Epicardial adipose tissue (EAT) remodeling is associated with atrial fibrillation (AF). However, there is limited research on the contribution of EAT to the risk of AF recurrence (AFR). The purpose of this research was to assess the relationship between the risk of AFR after radiofrequency catheter ablation and the volume and attenuation of the EAT.

Clinical application of targeted next-generation sequencing in pneumonia diagnosis among cancer patients.

Background: Cancer patients are highly susceptible to infections due to their immunocompromised state from both the malignancy and intensive treatments. Accurate and timely identification of causative pathogens is crucial for effective management and treatment. Targeted next-generation sequencing (tNGS) has become an important tool in clinical infectious disease diagnosis because of its broad microbial detection range and acceptable cost.

An pH-driven DNA nanodevice for impeding metastasis by selectively blocking cell signaling.

Invasion and metastasis dominate tumor progression, causing a substantial proportion of cancer-related deaths. However, the efficacy of current antimetastatic treatments is hampered by the dearth of targeted therapeutics. Recently developed synthetic-receptor toolkits offer potential for artificially regulating cellular behavior.

Photothermally Responsive Hydrogel Releases Basic Fibroblast Growth Factor to Promote the Healing of Infected Wounds.

The treatment of infected wounds is often complicated by bacterial infection and impaired scar healing. Antibiotics and growth factors are typically utilized to address these clinical challenges and expedite wound healing. However, the use of hydrogels containing these therapeutic agents is often restricted to complex cases and increases treatment costs considerably.

Chinese expert consensus on flow cytometric detection of hematological malignant cells in tissue samples.

Flow cytometry (FCM), characterized by its simplicity, rapid processing, multiparameter analysis, and high sensitivity, is widely used in the diagnosis, treatment, and prognosis of hematological malignancies. FCM testing of tissue samples not only aids in diagnosing and classifying hematological cancers, but also enables the detection of solid tumors. Its ability to detect numerous marker parameters from small samples is particularly useful when dealing with limited cell quantities, such as in fine-needle biopsy samples.

Advanced electrocatalysts for fuel cells: Evolution of active sites and synergistic properties of catalysts and carrier materials.

Proton exchange-membrane fuel cell (PEMFC) is a clean and efficient type of energy storage device. However, the sluggish reaction rate of the cathode oxygen reduction reaction (ORR) has been a significant problem in its development. This review reports the recent progress of advanced electrocatalysts focusing on the interface/surface electronic structure and exploring the synergistic relationship of precious-based and non-precious metal-based catalysts and support materials.

New hopes and challenges in targeted therapy and immunotherapy for primary central nervous system lymphoma.

Primary central nervous system lymphoma (PCNSL) is non-Hodgkin's lymphoma (NHL) confined to the central nervous system. Most of the patients eventually develop relapsed/refractory (R/R) PCNSL, and the overall prognosis for PCNSL remains dismal. Recently, gene sequencing, transcriptome sequencing, and single-cell sequencing platforms have provided a large amount of data revealing the mechanisms underlying the pathogenesis and drug resistance in PCNSL, including the activation of the NF-κB signaling pathway in tumor cells, tumor heterogeneity, and the immunosuppressive tumor microenvironment.

The role of efferocytosis in inflammatory bowel disease.

Efferocytosis is the process by which various phagocytes clear apoptotic cells. In recent years, an increasing body of evidence has emphasized the importance of efferocytosis in maintaining internal homeostasis. Intestinal macrophages play a crucial role in modulating intestinal inflammation and promoting tissue repair.

How does physical education influence university students' psychological health? An analysis from the dual perspectives of social support and exercise behavior.

Objective: Physical education, as a central component of educational systems, plays a unique role in enhancing the psychological well-being of university students. This study investigates the impacts of physical education on students' mental health and examines the mediating roles of social support and exercise behavior.

Methodology: A cross-sectional survey was conducted using the Physical Education Satisfaction Scale, SCL-90, the Social Support Questionnaire, and the International Physical Activity Questionnaire.

Epidemiology of Ocular Trauma and Predictive Modeling of Visual Outcomes: A 12-Year Retrospective Study at a Tertiary Hospital in China.

Background: Ocular trauma is a visually and economically devastating cause of visual loss. This study investigated the prevalence and clinical characteristics of ocular trauma in central and northern China, and assessed prognostic factors.

Methods: Cases of ocular trauma that underwent surgical treatment in a tertiary hospital in China between January 1, 2012, and December 31, 2023, were reviewed.