1 results match your criteria: "Zhejiang University Hangzhou 310027 PR China boliang1986@zju.edu.cn yexuesong@zju.edu.cn.[Affiliation]"
Ultra-low level detection of hepatocellular carcinoma global methylation using a AuNP modified carbon fiber microelectrode.
RSC Adv
April 2020
Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrument Science, Innovation Center for Minimally Invasive Technique and Device, Zhejiang University Hangzhou 310027 PR China
Hepatocellular carcinoma (HCC) is one of the most common cancerous diseases, with a low 5 year survival rate. Global hypomethylation drives genomic instability, which is regarded as one biomarker for early diagnosis. Long interspersed nucleotide element-1 (LINE-1) makes up around 17% of the genome, and could be regarded as a surrogate marker for global DNA methylation.
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