3 results match your criteria: "Zhangjiagang Hospital Affiliated to Suzhou University[Affiliation]"

Objective: To investigate the impact of retaining part of the urethral mucosa on postoperative urinary control, erectile function, and ejaculatory function in patients undergoing holmium laser enucleation of the prostate (HoLEP) surgery.

Methods: A retrospective analysis was conducted on 176 benign prostatic hyperplasia (BPH) patients who underwent surgical treatment at our hospital from January 2019 to January 2022, including 80 cases of modified HoLEP surgery and 96 cases of standard HoLEP surgery. Preoperative and postoperative clinical data were collected and analyzed.

View Article and Find Full Text PDF

Cyclin D1 has been identified as a proto-oncogene associated with the uncontrolled proliferation of tumor cells. This systematic review and meta-analysis aims to estimate the prognostic significance of cyclin D1 in multiple myeloma (MM) patients. We searched for qualified data in PubMed, Embase, and Web of Science up to February 2020.

View Article and Find Full Text PDF

The miR-875-5p inhibits SATB2 to promote the invasion of lung cancer cells.

Gene

February 2018

Zhangjiagang First People 's Hospital, Zhangjiagang Hospital Affiliated to Suzhou University, Zhangjiagang 215600, China. Electronic address:

Article Synopsis
  • The study highlights that miR-875-5p is up-regulated in patients with non-small cell lung cancer (NSCLC) and promotes tumor cell growth and spread by inhibiting SATB2.
  • CCK-8 assays indicate that introducing miR-875-5p mimics increases cell proliferation, while Transwell assays demonstrate enhanced invasion and migration of NSCLC cells.
  • Luciferase and western blotting assays confirm that miR-875-5p directly interacts with SATB2's 3' UTR, reducing its protein expression, suggesting that targeting miR-875-5p could be a viable treatment strategy for NSCLC.
View Article and Find Full Text PDF