Synthesis and antifungal evaluation of new azole derivatives containing 1,2,3-triazole.

Invasive fungal infections caused by are becoming increasingly serious and there is an urgent need for exploring new antifungal drugs. In the present work, a series of new azole derivatives containing a 1,2,3-triazole moiety have been prepared, and antifungal activity have been evaluated. The results revealed that most compounds showed excellent antifungal activity against SC5314 and drug-resistant SC5314-FR.