3 results match your criteria: "Yunnan Mental Hospital[Affiliation]"

A Review of Clinical Advances and Challenges in Clozapine-Induced Myocarditis.

Neuropsychiatr Dis Treat

March 2025

Department of Science and Education, The Affiliated Mental Health Center of Kunming Medical University, Yunnan Mental Hospital, Kunming, Yunnan Province, 650032, People's Republic of China.

Currently, the treatment of schizophrenia remains primarily pharmacological, with approximately 30% of patients diagnosed with treatment-resistant schizophrenia (TRS). Clozapine continues to be the first choice treatment for this subgroup of patients. As the preferred treatment, clozapine offers clear advantages in efficacy; however, its complex and troublesome adverse effects pose significant challenges for psychiatrists.

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Article Synopsis
  • This study aimed to evaluate the economic benefits of paliperidone palmitate in treating schizophrenia by analyzing data from 546 diagnosed patients over a year.
  • After 12 months, patients experienced an increase in outpatient visits and a decrease in hospitalizations, leading to reduced inpatient medical costs.
  • Overall, paliperidone palmitate treatment not only lowered hospitalization rates but also reduced indirect costs associated with lost productivity and other economic burdens.
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Previous studies showed that blood BDNF levels in mood disorders were reduced. However, little is known about the changes of BDNF and its precursor proBDNF in lymphocytes. In addition, earlier studies using commercial ELISA kits cannot distinguish mature BDNF from proBDNF.

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