5,192 results match your criteria: "Yueksek İhtisas Research and Training Hospital[Affiliation]"

Objective: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs, notably the skin, joints, and kidneys. The primary goal in managing SLE is to enhance patients' quality of life (QoL). Illness perception can influence QoL in patients with chronic disease.

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Family physicians are a pillar of the primary healthcare system, and their own mental well-being is integral to their performance. However, many studies have suggested a high prevalence of mental distress. The contributing factors include the emotional demands of the profession, work overload, budgetary constraints, loss of autonomy, and erosion of professional values.

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Safety of direct oral provocation in beta-lactam allergy.

Allergol Immunopathol (Madr)

September 2024

Division of Allergy and Immunology, Department of Pediatrics, Research and Training Hospital of Sakarya, Sakarya University, Medical Faculty, Adapazarı, Sakarya, Türkiye;

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Gibberellin-regulated protein allergy and orange-induced anaphylaxis.

Allergol Immunopathol (Madr)

September 2024

Division of Allergy and Immunology, Department of Pediatrics, Research and Training Hospital of Sakarya, Sakarya University, Medical Faculty, Adapazarı, Sakarya, Türkiye;

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Cold-induced urticaria and development of anaphylaxis.

Allergol Immunopathol (Madr)

September 2024

Division of Allergy and Immunology, Department of Pediatrics, Research and Training Hospital of Sakarya, Sakarya University, Medical Faculty, Adapazarı, Sakarya, Türkiye;

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Background: Spinal implants' longevity is crucial, but titanium alloys, while advantageous, lack strong bone integration. This study aimed to achieve better osseointegration rates by utilizing the ability of boron compounds to transform stem cells in the vertebra into osteoblasts.

Method: Twenty male albino rabbits were divided into control (n = 10) and experimental (n = 10) groups.

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Article Synopsis
  • The study assessed the effectiveness of high uterosacral ligament suspension (HUSLS) via vaginal-assisted natural orifice transluminal endoscopic surgery (vNOTES) in patients with pelvic organ prolapse or those needing prevention after a hysterectomy.
  • A total of 55 women participated, with significant improvements in prolapse measurements and a success rate of 96.4% over an average follow-up of 23.5 months.
  • Complications were minimal, with only one case of bladder injury and a high patient satisfaction rate of 98.1%.*
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Article Synopsis
  • Behçet's disease (BD) is a systemic condition that can affect children and may lead to serious cardiovascular issues, like early atherosclerosis, due to ongoing inflammation.
  • This study compared 30 children with juvenile BD to 20 healthy controls, measuring their epicardial adipose tissue (EAT) and carotid intima-media thickness (CIMT), finding that EAT was significantly thicker in BD patients, while CIMT did not show notable differences.
  • The findings suggest that increased EAT thickness could indicate a risk for early atherosclerosis in children with BD, highlighting the need for further research to explore screening for these risks in larger groups.
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Radiocontrast media-induced sialadenitis.

J Allergy Clin Immunol Pract

September 2024

Division of Allergy and Immunology, Department of Pediatrics, Research and Training Hospital, Sakarya University Medical Faculty, Adapazarı, Sakarya, Türkiye. Electronic address:

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Purpose: Fasciotomy is a surgical procedure that involves the incision of fascial compartments in the body to relieve pressure, prevent tissue damage, and maintain blood flow. This study aimed to investigate the effectiveness of the Bogota Bag technique in closing fasciotomy wounds in patients with lower limb compartment syndrome.

Methods: A prospective cohort study was conducted between October 2022 and October 2023 to document our experience in employing the Bogota Bag technique for fasciotomy closure.

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Background: Migraine is a primary headache defined as moderate-to-severe pain lasting 4 to 72 h, ranking 2nd among the disabling conditions for both genders regardless of the age and the greater occipital nerve (GON) block has been reported as an efficient treatment method for migraine. The present study aims to evaluate and compare the efficiency of the two methods of GON block, i.e.

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The aim of this study was to construct the sixth in a series of guidelines on the treatment of urolithiasis by the International Alliance of Urolithiasis (IAU) that by providing a clinical framework for the management of pediatric patients with urolithiasis based on the best available published literature. All recommendations were summarized following a systematic review and assessment of literature in the PubMed database from January 1952 to December 2023. Each generated recommendation was graded using a modified GRADE methodology.

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Aim: Although vitamin D deficiency in smokers has a greater risk of low birth weight than vitamin D deficiency or smoking alone, there is no study searching birth weight in vitamin D deficient passive smokers. We evaluated the effect of vitamin D deficiency on birth weight in active and passive smokers. Additionally, we aimed to determine the predictive role of vitamin D for low birth weight in smokers.

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Article Synopsis
  • The study investigates the psychological issues and maternal interactions among infants and toddlers with nonsyndromic clefts of the lip and/or palate (NSCLP) to identify correlations with developmental challenges.
  • The research involved 26 children with NSCLP compared to 52 healthy children, focusing on psychiatric diagnostics, language development, and articulation.
  • Results show a higher prevalence of speech and language disorders, emotional disorders, and problematic mother-child relationships in NSCLP children, suggesting that improving maternal interactions could be crucial in managing their psychological well-being.
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Background: Gallbladder perforation (GBP) is a rare but life-threatening complication of acute cholecystitis. Despite advancements in imaging technology and biochemical analysis, perforations are still diagnosed intraoperatively in some cases. This situation has revealed the need for new markers in the diagnosis of perforation.

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Can the efficacy of a medical treatment be predicted based on the type of idiopathic premature ventricular contraction?

J Electrocardiol

September 2024

Cardiology Department, Istanbul Medeniyet University Faculty of Medicine, Goztepe Training and Research Hospital, Dr. Erkin street, 34722 Istanbul, Turkey.

Background: Premature ventricular contractions (PVCs) are common arrhythmias with diverse clinical implications. This retrospective study aimed to evaluate the efficacy of medical treatments using various clinical, imaging, and electrocardiographic parameters in patients with idiopathic PVCs.

Methods: A total of 1051 patients with idiopathic PVCs were retrospectively analyzed.

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Background: Epilepsy is the most prevalent chronic neurological condition in childhood, affecting approximately 0.5%-1% of children worldwide.

Objective: This study aimed to (1) develop an "Epilepsy Knowledge Scale for Parents", (2) evaluate the content validity of the scale, and (3) assess its psychometric properties.

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To evaluate and compare the quality and comprehensibility of answers produced by five distinct artificial intelligence (AI) chatbots-GPT-4, Claude, Mistral, Google PaLM, and Grok-in response to the most frequently searched questions about kidney stones (KS). Google Trends facilitated the identification of pertinent terms related to KS. Each AI chatbot was provided with a unique sequence of 25 commonly searched phrases as input.

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Purpose: To discern whether reduced infection rates were attributed to antiseptic solutions or mechanical rectal irrigation.

Patients And Methods: After receiving ethical approval, the study included patients who underwent transrectal prostate biopsy due to elevated PSA or abnormal digital rectal examination findings, and prostate cancer under active surveillance, at Tepecik Training and Research Hospital between April 2022 and June 2023. Standard antibiotic prophylaxis was administered.

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Background: To compare the clinicopathological characteristics of nonmetastatic breast cancer patients with and without BRCA variations and to investigate the impact of BRCA variations on prognosis.

Methods: This retrospective single-center study involved an analysis of 938 patients with localized or locally advanced breast cancer who underwent BRCA variation testing. The patients were divided into three groups: 757 were without BRCA variation, 64 were with BRCA1 variation, and 117 were with BRCA2 variation.

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: The frontal QRS-T angle is a novel parameter of myocardial repolarization. Weight gain during pregnancy and physiological changes during a cesarian section may affect the frontal QRS-T angle. We aimed to assess the effect of body mass index (BMI) on the frontal QRS-T angle in pregnant women undergoing cesarean section with spinal anesthesia.

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The primary objective of this in vitro study was to prevent the risk of toxicity associated with bupivacaine, widely used in clinical practice, by using magnesium (Mg), a readily available and cost-effective element, as an adjuvant. We hypothesized that Mg might exhibit a protective effect against cytotoxicity in a colon cell culture model under conditions of bupivacaine-induced LAST. Our secondary aim was to investigate its effect on genotoxicity, apoptosis, and iROS.

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Introduction: Breast cancer, the most prevalent cancer among women, often requires chemotherapy with docetaxel being a key agent. However, docetaxel-inducted peripheral neuropathy (DIPN) can adversely impact patients' quality of life. This case discusses an unusual instance of severe DIPN leading to wheelchair dependence in a 35-years old woman undergoing neoadjuvant treatment for locally advanced breast cancer.

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Comparison of the BIG Score and Pediatric Trauma Score for Predicting Mortality.

Pediatr Emerg Care

December 2024

From the Department of Emergency Medicine, University of Health Sciences, Haseki Research and Training Hospital, Istanbul, Türkiye.

Objectives: The BIG score (base deficit + [2.5 × international normalized ratio] + [15 - Glasgow Coma Score]) was compared with the Pediatric Trauma Score (PTS) for predicting mortality in pediatric patients with multiple trauma.

Methods: This retrospective, single-center study included 318 consecutive pediatric patients (aged 1-18 years) with multiple trauma who were admitted to the emergency department between January 1, 2021, and December 31, 2023.

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