4 results match your criteria: "Yonsei University Graduate School Seoul[Affiliation]"
Article Synopsis
- Heart degenerative diseases are hard to treat because the heart has a poor ability to regenerate lost cells called cardiomyocytes.
- Direct cellular reprogramming using small molecules offers a safer way to create functional cardiomyocytes without modifying genes, but the current methods are not very efficient and lead to immature cells.
- This study found that delivering mitochondria from high-energy organs can improve the maturity and functionality of chemically induced cardiomyocyte-like cells (CiCMs), which may enhance their potential use in regenerative medicine.
Knockdown of E2F4 suppresses the growth of ovarian cancer cells through the cell cycle pathway.
Int J Clin Exp Pathol
August 2021
Department of Obstetrics and Gynecology, Yonsei University Graduate School Seoul, Republic of Korea.
Ovarian cancer remains one of the major causes of death from gynecologic cancer in developed countries. The E2F family has been shown to have a central role in the control of cell proliferation, differentiation, and cell cycle progression in various types of cancer. Despite advances in cancer research, the carcinogenic role of E2F transcription factor 4 (E2F4) in ovarian cancer remains unclear.
View Article and Find Full Text PDFPrognostic impact of high p16/cyclin D1 index in breast cancer.
Int J Clin Exp Pathol
June 2019
Department of Pathology, Yonsei University College of Medicine, Severance Hospital Seoul, Republic of Korea.
Proteins p16 and cyclin D1 (CCND1) are known to tightly regulate the G1/S transition during the cell cycle, but their role in breast cancer development and progression is not clear. We investigated 224 cases of breast cancer from the Kangbuk Samsung Medical Center between 2000-2005. Expression levels of p16 and CCND1 were assessed by tissue microarray-based immunohistochemistry.
View Article and Find Full Text PDF[Association between Emotional Labor, Emotional Dissonance, Burnout and Turnover Intention in Clinical Nurses: A Multiple-Group Path Analysis across Job Satisfaction].
J Korean Acad Nurs
December 2017
Department of Preventive Medicine · Institute of Occupational and Environmental Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Purpose: This study was conducted to investigate the influence of emotional labor, emotional dissonance, and burnout on nurse's turnover intention and examine the effect of job satisfaction on the relationships among emotional labor, emotional dissonance, burnout, and turnover intention.
Methods: The sample consisted of 350 nurses recruited from 6 general hospitals in 2 cities in Korea. A multiple-group analysis was utilized.