1 results match your criteria: "Yonsei University College of Medicine (H.J.[Affiliation]"
Real-World Incidence of Incident Noninfectious Uveitis in Patients Treated With BRAF Inhibitors: A Nationwide Clinical Cohort Study.
Am J Ophthalmol
November 2024
From the Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine (H.J., C.S.L., S.H.B., S.S.K., Y.J.K.), Seoul, Republic of Korea. Electronic address:
Article Synopsis
- The study investigates the incidence of noninfectious uveitis among skin melanoma and lung cancer patients receiving different treatments: BRAF inhibitors, immune checkpoint inhibitors (ICIs), or conventional chemotherapy.
- An analysis of over 77,000 patients showed that those on BRAF inhibitors had a significantly higher risk of uveitis (2.27%) compared to those on ICIs (0.35%) or chemotherapy (0.33%).
- The adjusted risk indicates that patients on BRAF inhibitors were over 7 times more likely to develop uveitis compared to those not treated with BRAF inhibitors, with even higher risks noted after matching for similar characteristics.