1,008 results match your criteria: "Yeditepe University Koşuyolu Hospital[Affiliation]"

Pulsed field ablation (PFA) is a catheter-based procedure that utilizes short high voltage and short-duration electrical field pulses to induce tissue injury. The last decade has yielded significant scientific progress and quickened interest in PFA as an energy modality leading to the emergence of the clinical use of PFA technologies for the treatment of atrial fibrillation. It is generally agreed that more research is needed to improve our biophysical understanding of PFA for clinical cardiac applications as well as its potential as a potential alternative energy source to thermal ablation modalities for the treatment of other arrhythmias.

View Article and Find Full Text PDF

Transtemporal Endoscopic Deep Plane Face Lift.

Plast Reconstr Surg Glob Open

January 2025

Plastic, Reconstructive and Aesthetic Surgery Department, Yeditepe University Hospital, Istanbul, Turkey.

Background: Facial aging involves multifactorial changes affecting the bone, superficial musculoaponeurotic system, fat pads, and skin, primarily manifesting as the downward displacement of these structures. The transtemporal endoscopic deep plane face lift (TEDPF) suggests a vertical lifting method, targeting these issues without a preauricular incision.

Methods: A retrospective study was conducted on 140 patients (133 women and 7 men) 33-67 years of age who underwent TEDPF from February 2020 to March 2023.

View Article and Find Full Text PDF

Introduction: This study aimed to assess the clinical practices and attitudes towards Hashimoto's thyroiditis (HT) among pediatric (PEs) and adult endocrinologists (AEs).

Methods: The members of Turkish Society for Pediatric Endocrinology and Diabetes (n=502) and the Society of Endocrinology and Metabolism of Türkiye (n=910) were invited to participate in an online survey.

Results: Of the respondents (n=168), 72.

View Article and Find Full Text PDF

Background: Quantitative Susceptibility Mapping (QSM) provides a non-invasive post-processing method to investigate alterations in magnetic susceptibility (χ), reflecting iron content within brain regions implicated in neurodegenerative diseases (NDDs).

Purpose: To investigate alterations in thalamic χ in patients with NDDs using QSM.

Study Type: Systematic review and meta-analysis.

View Article and Find Full Text PDF

Objectives: To describe a novel technique for dissecting cadaver brains without damaging medial brain structures and surfaces, ensuring preservation for neuroanatomical study and training.

Methods: Ten adult cadaveric brains were dissected using the supracerebellar suprapineal approach under an operative microscope with 6x to 40x magnification. This approach allowed for the separation of the brain into two hemispheres while providing direct visualization of the third ventricle and preserving midline structures.

View Article and Find Full Text PDF

Background: In the 21st century, disasters (particularly earthquakes, which remain the leading cause of death) continue to be among the foremost issues requiring global emergency response. While the impact of advancing technologies on the environmental and human damage caused by earthquakes is still a subject of debate, search and rescue (SAR) teams and emergency departments (ED), specifically emergency physicians (EPs), play a crucial role in the most acute management of the effects of these earthquakes on human life. This study aims to examine the injury dynamics of two catastrophic earthquakes that occurred in Turkey 24 years apart from the perspective of EPs, utilizing archival records from the SAR teams in which EPs served.

View Article and Find Full Text PDF

Background: Microvascular decompression (MVD) is the gold-standard surgical treatment for cranial nerve compression disorders, including trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia (GPN). This review synthesizes historical milestones, recent advances, and evolving techniques in MVD, with a primary focus on these conditions.

Methods: A comprehensive literature review was conducted using databases such as PubMed, SpringerLink, Google Scholar, BioMed Central, Scopus, and ScienceDirect.

View Article and Find Full Text PDF

Background And Objectives: The middle fossa approaches are tremendously versatile for treating small vestibular schwannomas, selected petroclival meningiomas, midbasilar trunk aneurysms, and lesions of the petrous bone. Our aim was to localize the internal acoustic canal and safely drill the petrous apex with these approaches. This study demonstrates a new method to locate the internal acoustic canal during surgery in the middle fossa.

View Article and Find Full Text PDF

Mechanistic insights into cardiac regeneration and protection through MEIS inhibition.

Turk J Biol

October 2024

Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, İstanbul, Turkiye.

Article Synopsis
  • MEIS1 is a key regulator in stopping cardiomyocyte cell division and is a potential target for heart-related therapies.
  • Inhibition of MEIS1 through new small molecules (MEISi-1 and MEISi-2) boosts the growth and division of neonatal cardiomyocytes significantly compared to untreated cells.
  • MEIS1 inhibition not only reduces the expression of certain target genes but also enhances important cardiac-specific gene expression, suggesting these inhibitors could play a vital role in heart regeneration treatments.
View Article and Find Full Text PDF

Purpose: This study aimed to translate the Maternal Health Literacy Inventory in Pregnancy (MHELIP) scale into Turkish and evaluate its validity and reliability for use in the Turkish population.

Methods: The participants in this methodological study included 250 pregnant women who presented to the antenatal clinic of the Florence Nightingale Hospital in Istanbul, Turkiye. Content validity was assessed using expert approval.

View Article and Find Full Text PDF

Purpose: The aim of this study was to investigate the radiobiological effects underlying the inhibition of breast cancer (BCa) following radiotherapy in nude mice models, and to evaluate the impact of changes in immunohistochemical parameters induced by FF and FFF beams.

Materials And Methods: The study included thirty-six adult nude mouse models, which were randomly assigned to five groups: control (G1), breast cancer (BCa) (G2), FF-400 MU/min (G3), FFF-1100 MU/min (G4), and FFF-1800 MU/min (G5). The control group received neither radiation nor treatment, while the BCa group had a cancer model without radiation.

View Article and Find Full Text PDF

Objective: The aim of this study was to evaluate the relationship between subclinical lymphedema identified prior to surgical intervention and clinical lymphedema observed in the late period, the incidence of lymphedema in our cohort, and the associated risk factors.

Materials And Methods: This prospective study was conducted with early-stage breast cancer patients who had been enrolled in a previous study. For diagnosing lymphedema, physical examination, L-Dex® score, and circumferential measurement was used.

View Article and Find Full Text PDF

Objectives: This study aims to investigate the efficacy of epidermis dermis fascia (EDF) kinesiotaping (KT) technique on pain intensity, number of active trigger points (TrPs), cervical range of motion (ROM) angles, and disability levels in patients with myofascial pain syndrome (MPS) on upper trapezius (UT) muscle.

Patients And Methods: Between January 2019 and January 2020, a total of 180 patients (21 males, 159 females; mean age: 35.9±9.

View Article and Find Full Text PDF

Background: The aim of this study is to determine the effect of Korean hand acupressure applied after thyroidectomy on postoperative pain, nausea, vomiting, and retching of number and severity.

Materials And Methods: The type of study is a randomized study with a post-test-control group. The protocol was prepared according to the SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 checklist.

View Article and Find Full Text PDF

Background: The closure of a patent foramen ovale (PFO) using transseptal puncture has particular advantages and disadvantages. Thus, transseptal puncture should be re-evaluated in detail.

Aims: We aimed to assess the effectiveness of the detailed transseptal puncture technique in patients who underwent PFO closure due to cryptogenic stroke or transient ischemic attack in terms of residual shunts and atrial fibrillation.

View Article and Find Full Text PDF

Background: This study aims to investigate the impact of combining crush fluid resuscitation with gelsolin treatment on renal function in a rat model of crush syndrome.

Methods: Twenty-four adult female Wistar albino rats were randomly assigned to one of three groups for crush syndrome treat-ment: Control (C) group, gelsolin + crush fluid (gel) group, and crush fluid only (CF) group, each containing eight rats. Sedated rats underwent unilateral hind limb compression of 2 kg using a compression device, maintained for five hours.

View Article and Find Full Text PDF

Objective: Cessation of gonadotropin stimulation might affect follicular growth in patients in POSEIDON groups 3 and 4, which are unresponsive to high-dose stimulation.

Materials And Methods: In this retrospective study, data were extracted from the medical records of patients treated at the Acıbadem Maslak Hospital Assisted Reproductive Technologies Unit between November 2010 and December 2020. Eighty-five patients who fulfilled the inclusion criteria were included in the study.

View Article and Find Full Text PDF

Atrial fibrillation (AF) is the most common cardiac dysrhythmia and a common cause of ischemic stroke. Stroke prevention with oral anticoagulation (OAC) is the cornerstone of AF management. Patients and their treating physicians may have different views on different attributes of OACs.

View Article and Find Full Text PDF

BACKGROUND Cartilage injuries are challenging to treat due to limited self-healing. Standard treatments often lead to the formation of less durable fibrocartilage. Caffeic acid phenethyl ester (CAPE), a polyphenolic compound, can improve cartilage repair.

View Article and Find Full Text PDF

The General Practitioner Assessment of Cognition (GPCOG) was explicitly developed as a brief cognitive screening tool for general practitioners. It consists of a patient section testing cognition and an informant section asking historical questions. This study aimed to test the validity and reliability of the Turkish version of GPCOG-Tr on older Turkish adults.

View Article and Find Full Text PDF

Virtual anatomical atlas of the deep brain nuclei.

Neurosurg Rev

November 2024

Department of Neurosurgery, Yeditepe University, School of Medicine Kosuyolu Hospital, Kosuyolu Street, Kadıkoy, İstanbul, 34718, Türkiye.

This study aims to improve understanding of the anatomy of the deep brain nuclei relevant to deep brain stimulation as well as stereotactic lesioning procedures, including radio frequency, high-focused ultrasound, and radiosurgery. We created interactive, three-dimensional virtual models from cadaveric dissections and radiological segmentation. We used five brain specimens (ten hemispheres) obtained from routine autopsies, prepared according to Klingler's method.

View Article and Find Full Text PDF

Objective: Despite the growing number of female medical students, there remains a significant disparity between the number of female and male neurosurgeons. This study aims to determine if this trend is also evident among medical students, examine how various medical schools worldwide are addressing this issue, and propose potential solutions.

Methods: The data includes anonymous baseline information from congress registrations, the abstract submission system, and 2 surveys designed to assess student experiences before and after the congress.

View Article and Find Full Text PDF

Objective: This study was conducted to determine the relationship between bone mineral density, vitamin D level, and sleep quality in female patients with osteoporosis.

Methods: This descriptive correlational study included a total of 318 women diagnosed with osteoporosis. The data were collected using a patient identification form, including items for the plasma vitamin D level and bone mineral density score obtained by the dual-energy X-ray absorptiometry method, and the Pittsburgh Sleep Quality Index.

View Article and Find Full Text PDF
Article Synopsis
  • Computational neurosurgery combines artificial intelligence and computational modeling to enhance the diagnosis and treatment of neurosurgical conditions, aiming to advance clinical neurosciences.
  • The field seeks to integrate ethical considerations to ensure that the use of AI is conducted responsibly and prioritizes patient care, ultimately aiming to prevent errors in treatment.
  • This initiative serves as a guide for practitioners, ethicists, and scientists in the application of ethical standards within computational neurosurgery.
View Article and Find Full Text PDF
Article Synopsis
  • The text discusses a specific gene, bhlhe22, which plays a crucial role in retinal and brain development by encoding a transcription factor involved in neural differentiation.
  • Researchers identified eleven individuals from nine families with variants in this gene linked to a neurodevelopmental disorder characterized by speech limitations, severe motor impairments, intellectual disabilities, and other neurological symptoms, including agenesis of the corpus callosum.
  • Genetic analysis revealed that some individuals had harmful missense variants in a critical region of the gene, while others had a recurring frameshift mutation, suggesting that these genetic changes lead to severe cognitive and motor deficits associated with this newly recognized disorder.
View Article and Find Full Text PDF