Efficacy of the Roy Adaptation Model with smartphone training in reducing urinary tract infection in pediatric clean intermittent catheterization: a prospective study.

Purpose: Study aimed to compare incidence of urinary tract infection (UTI), type of bacteria grown, development of antibiotic resistance over 2 years in children whose caregivers underwent training based on the Roy Adaptation Model with an android phone application for patients clean intermittent catheterization (RAMACIC) versus those whose caregivers received routine training in hospital.

Method: This study was conducted as a descriptive, prospective study with 40 patients and caregivers between October 2021 and 2023 as a continuation of a previously conducted randomized controlled experimental study by the researchers. Data were collected the "Participant Form," and "Urine Test Form" analyzed with the SPSS 22 package.

The relationship between sexual health literacy and sexual function of women with diabetes mellitus: a cross-sectional study.

Background: Sexual dysfunction (SD) is a complication of poorly managed diabetes mellitus (DM). To prevent SD, patients should develop sexual health literacy (SHL).

Objective: This study investigated the relationship between SHL and SD in women with DM.

Morphological and Anatomical Deformities of Hirudo verbana, Carena 1820 (Annelida, Hirudinea) After Feeding: Light and Electron Microscopic Analysis.

Leeches are widely used as model organisms in scientific studies and medical treatments. Medical leeches are hematophagous parasites that usually feed on the blood of their hosts. Some leeches show deformities, usually after feeding.

Determinants of Problem-Solving Skills of Nursing Students: Solution-Focused Thinking Skills and Emotional Intelligence.

Background: Problem-solving skills are some of the leading strategies for dynamism in the content and quality of nursing care.

Aim: The present study is aimed at determining nursing students' problem-solving, solution-focused thinking, and emotional intelligence levels and investigating the relationship between their problem-solving skills and these variables.

Methods: The study comprised 305 nursing students in Turkey.

Evaluating diagnostic performance: A comparative analysis of cell-free DNA and serological test in hepatic cystic Echinococcosis.

Cystic Echinococcosis (CE) is a zoonotic disease caused by sensu lato. Diagnosing CE primarily relies on imaging techniques, and there is a crucial need for an objective laboratory test to enhance the diagnostic process. Today, cell-free DNAs (cfDNAs) have gained importance regarding their biomarker potential.

Correlation of Total Polyphenol and Flavonoid Content With Antioxidant Activity of Caucasian Bee Honey.

Honey is a natural product gathered by honeybees from the pollen and nectar of various plants and flowers. The homeland of the Caucasian honey bee, which draws attention with its honey production and is one of the most productive bee races known in the world, is Northeastern Anatolia in Türkiye. This study aims to determine and correlate the phenolic content and antioxidant activity of 54 honey samples obtained from the most important gene centers of the Caucasian bee in Türkiye.

Determination of paclobutrazol using square wave voltammetry based on a molecularly imprinted polymer and boron-doped copper oxide/graphene nanocomposite.

In the present study, a novel voltammetric sensor based on a boron-doped copper oxide/graphene (B-CuO-Gr) nanocomposite and molecularly imprinted polymer (MIP) was developed for the detection of paclobutrazol (PAC) in apple and orange juice samples. The B-CuO-Gr nanocomposite was prepared using sol-gel and calcination methods. After modifying glassy carbon electrodes with the B-CuO-Gr nanocomposite, PAC-imprinted electrodes were prepared in the presence of 100.

Maximizing phonation: impact of inspiratory muscle strengthening on vocal durations and pitch range.

Background: This study investigated the acute effects of inspiratory muscle warm-up (IWU) on vocal performance in singers. Proper vocal and respiratory warm-up can enhance vocal range, quality, and endurance. The aim was to determine whether IWU improves maximum phonation time and pitch range, contributing to better voice production efficiency (vocal efficiency) and reduced fatigue.

Antimycobacterial activity of luteolin in resistant Mycobacterium tuberculosis isolates and cytotoxicity on L929 cells.

Mycobacterium tuberculosis (M. tuberculosis) bacteria can cause oxidative stress and the production of inflammatory cytokines, creating an environment that enhances tumour formation, progression and metastasis. Epidemiological studies have found a link between lung cancer and tuberculosis (TB), but the cellular mechanism is still unclear.

Therapeutic Ultrasound Modulates Cell Proliferation and Proinflammatory Cytokine Levels in Osteoarthritic Chondrocytes.

The development and progression of osteoarthritis (OA) are believed to involve inflammation. This study aimed to investigate the effects of applying therapeutic ultrasound (US) to human osteoarthritic chondrocytes in continuous and pulsed modes on cell proliferation and proinflammatory cytokine levels. Human osteoarthritic chondrocytes (HC-OA 402OA-05a) were proliferated in appropriate media and then seeded into culture plates.

Optimized microwave-assisted extraction and characterization of spray dried Luffa aegyptiaca nanomucilage: Physicochemical properties, biological activities, and anticancer efficacy against MCF-7 human breast cancer cells.

Microwave-assisted extraction conditions were optimized using response surface methodology to evaluate the effects of extraction parameters on the yield and carbohydrate content of Luffa aegyptiaca mucilage. Extraction at 540 W for 2 min with a 1:20 (g/mL) was determined as the optimal parameter, resulting in a maximum yield of 5.90 % (w/w) with 63 % carbohydrate content consisting of glucose, galactose, maltose, mannose, and galacturonic acid, with structural linkages of β (1 → 4) and β (1 → 6) glycosidic bonds.

Detection of glycopeptide resistance and virulence genes in enterococci isolated from cheese and investigation of the clonal relationship of E. faecium species with rectal surveillance isolates.

Objective: This study aimed to investigate the presence of glycopeptide resistance and virulence genes in Enterococcus spp. isolated from cheese and the clonal relationship of E. faecium species with rectal surveillance isolates.

Factors related to the decision to perform synchronized cardioversion for supraventricular tachyarrhythmias by prehospital emergency medical services workers.

Background: While clinical indicators for synchronized cardioversion in regular supraventricular tachycardias are well-established, their application by prehospital emergency medical services (EMS) still needs to be explored.

Objective: The purpose of this study was to evaluate the factors influencing the decision-making process of prehospital EMS personnel to perform synchronized cardioversion in adults with narrow QRS regular tachyarrhythmias.

Methods: This descriptive study included 598 paramedics actively engaged in prehospital EMS.

Risk Assessment for Preeclampsia in the Preconception Period Based on Maternal Clinical History via Machine Learning Methods.

: This study was aimed to identify the most effective machine learning (ML) algorithm for predicting preeclampsia based on sociodemographic and obstetric factors during the preconception period. : Data from pregnant women admitted to the obstetric clinic during their first trimester were analyzed, focusing on maternal age, body mass index (BMI), smoking status, history of diabetes mellitus, gestational diabetes mellitus, and mean arterial pressure. The women were grouped by whether they had a preeclampsia diagnosis and by whether they had one or two live births.

Synthesis, Characterization, and Investigation of Corona Formation of Dipeptide-Based Nanomaterials.

Peptide-based nanomaterials can be easily functionalized due to their functional groups, as well as being biocompatible, stable under physiological conditions, and nontoxic. Here, diphenylalanineamide-based nanomaterials (FFANMs) were synthesized, decorated with Ca ions to set the surface charge, and characterized for possible use in gene delivery and drug release studies. FFANMs were characterized by SEM, TEM, dynamic light scattering (DLS), and LC-MS/MS.

Exploring anticancer properties of new triazole-linked benzenesulfonamide derivatives against colorectal carcinoma: Synthesis, cytotoxicity, and in silico insights.

This study reports the design, synthesis, and characterization of a novel series of benzene sulfonamide-triazole hybrid derivatives, to evaluate their anticancer potential against colorectal cancer. The synthesized compounds were characterized using NMR and HRMS spectroscopic techniques. In vitro cytotoxicity assessments revealed that compounds 5g and 5j exhibited significant anticancer effects.

Comparative effects of dexpanthenol and thymoquinone on colistin-induced neurotoxicity in rats.

Colistin is used as a last-line treatment for multidrug-resistant gram-negative bacilli. Neurotoxicity limits clinic use of colistin. The use of colistin causes oxidative stress and inflammation.

Predicting Live Weight for Female Rabbits of Meat Crosses From Body Measurements Using LightGBM, XGBoost and Support Vector Machine Algorithms.

Prediction of body weight (BW) using biometric measurements is an important tool especially for animal welfare and automatic phenotyping tools that needs mathematical models. In this study, it was aimed to predict the BW using body length (BL), chest girth (CG) and width of the waist (WW) for rabbits of the maternal form of Hyla NG. The standard rabbit-raising practices were applied for the animals.

Multifunctional theranostic glyconanoprobes for synergistic eradication of breast cancer.

Theranostic agents hold great promise for personalized medicine by combining diagnostic and therapeutic functions. Herein, two novel multifunctional theranostic glyconanoprobes targeting breast cancer were engineered for synergistic dual chemo-gene therapy and triple chemo-gene-photothermal therapy. Upconversion nanoparticles (UCNPs) were prepared and coated with a Dox-loaded glycopeptide polymer (P-Dox) to form UCNP@P-Dox for improving stability.

A novel approach to prioritizing health technology investments using integrated AI-based ranking model.

Purpose: Health technologies are an issue that directly affects the sustainability and quality of health services. Due to budget constraints, it is not financially possible for businesses to apply comprehensive improvement strategies to all these criteria. In this case, it is possible for businesses to implement more priority strategies.

Impact of hopelessness on migration intentions of nursing students: a path analysis.

Background: Brain drain refers to the migration of qualified professionals to developed countries in search of better living and working conditions, and has become a global concern, particularly in the healthcare sector. Migration of highly skilled nurses results in increased workload for the remaining nursing staff, limited access to quality healthcare services, and contributes to disparities in healthcare. Therefore, nursing students represent a critical demographic group for understanding the drivers of brain drain in the healthcare sector.

Assessing body awareness and upper extremity functionality in breast cancer survivors with and without lymphedema: a comparative analysis with healthy controls.

Purpose: To determine whether body awareness and upper extremity functionality are affected in patients with or without lymphedema development after breast cancer surgery (BCS) in comparison with individuals without a history of cancer.

Methods: The study included a total of 102 individuals, including 34 who developed lymphedema after BCS (mean age: 43.88 ± 12.

The Effect of Aromatherapy Massage on Cramp Frequency, Pain Intensity, and Quality of Life in Hemodialysis Patients With Muscle Cramps: A Randomized, Placebo-Controlled, Mixed Study.

Muscle cramps, which are frequently encountered in hemodialysis patients, affect individuals bio-psycho-socially, limit their activities of daily living, and reduce their quality of life. In this study, we aimed to evaluate the effects of aromatherapy massage applied in 12 sessions over 4 weeks on cramp frequency, pain severity, and quality of life. The study was conducted as a pretest-posttest, randomized controlled, and single-blinded using a quantitative and qualitative research design.

Effect of Medial Olivocochlear Efferents on Speech Discrimination in Noise in Multiple Sclerosis.

Background: Patients with multiple sclerosis (MS) experience difficulties in understanding speech in noise despite having normal hearing.

Aim: This study aimed to determine the relationship between speech discrimination in noise (SDN) and medial olivocochlear reflex levels and to compare MS patients with a control group.

Material And Methods: Sixty participants with normal hearing, comprising 30 MS patients and 30 healthy controls, were included.