Effect of propolis supplementation on cadmium toxicity associated with renal and hepatic dysfunction in rats.

Cadmium (Cd), one of the toxic heavy metals, is of great importance for public health due to its use in many industrial areas. Propolis is a natural product with antioxidant and anti-inflammatory properties collected from plants by honey bees. The aim of this study was to investigate the protective role of propolis against the potential toxic effects of cadmium chloride in blood, liver and kidney tissues.

Metabolic syndrome index measurement tool (MSI): scale development, reliability and validity study.

Aim: Identifying the risks of metabolic syndrome (MetS) can lead to early targeted interventions and thus contribute to improved quality of life by reducing the risk of developing MetS, diabetes or heart disease in the future. We aimed to develop a valid and reliable measurement tool to measure the MetS risk of the population.

Materials And Methods: In the methodological study, an item pool was created by reviewing the literature.

Enhancing diabetic rat peripheral nerve conduction velocity parameters through the potent effects of MitoTEMPO.

The efficacy of MitoTEMPO, a mitochondria-targeted antioxidant, in altering nerve fiber conduction properties within the sciatic nerve of streptozotocin (STZ)-induced diabetic rats, a model for diabetic neuropathy characterized by myelinated fiber atrophy and nodal abnormalities. Utilizing the STZ-induced diabetic rat model, we assessed the impact of MitoTEMPO on nerve function through compound action potential (CAP) analysis and histological evaluation. Key indicators such as maximum depolarization (MD), CAP area, and conduction velocity distribution (CVD) were measured to gauge MitoTEMPO's neuroprotective effects, alongside physical parameters like weight and blood glucose levels.

Roles of NET Peptides With Known Antimicrobial Activity and Toxicity in Immune Response.

Antimicrobial peptides (AMPs) are crucial components of the innate immune system in all living organisms, playing a vital role in the body's defense against diseases and infections. The immune system's primary functions include preventing disease-causing agents from entering the body and eliminating them without causing harm. These peptides exhibit broad-spectrum activity against bacteria, viruses, fungi, parasites, and cancer cells.

Immunomodulatory properties of Giloy () leaves and its applications in value-added products.

In Ayurvedic texts, Giloy ( have been known as the most potent and important medicinal product. Giloy leaves have been used for centuries to cure various ailments and diseases in the human body. This review highlights that giloy leaves have immunomodulatory properties and can be used to develop functional food products.

Exploration of Agrocybe aegerita mushroom polysaccharide-polyphenolic complex: Functional properties, binding efficiency, and biological activities.

This study investigates the functional and biological activities of a polysaccharide-polyphenolic complex derived from the edible mushroom Agrocybe aegerita. Polyphenols (AMP) were extracted using a modified solvent evaporation technique, and polysaccharides (AMPP) were extracted using enzyme-assisted methods, yielding 8.02 %.

Long-term outcomes of Türkiye's first population-based mammography screening program: a decade of breast cancer detection and survival analysis in Bahçeşehir.

Background: The Bahçeşehir population-based mammography screening program (BMSP) is an example of Türkiye's first population-based screening program. This study aims to reveal the successful implementation of population-based secreening program in one of the low- and middle-income countries, Türkiye and long-term results of patients diagnosed with breast cancer during BMSP.

Methods: This study was conducted between 2009 and 2019, in the Bahçeşehir county of Istanbul.

Immunohistochemical examination of PNAd, α4β1 integrin and MUC-2 expressions in the secretary phase endometrium of women diagnosed with recurrent implantation failure.

Objective: Successful embryo implantation is contingent upon the intricate interaction between the endometrium and the blastocyst. Recurrent implantation failure (RIF) signifies the clinical challenge of failing pregnancy post-transfer of high-quality embryos, fresh or frozen, in at least three in vitro fertilization (IVF) cycles, often in women under 40 years. Recent studies identify impaired blastocyst maternal tissue communication among recurrent implantation failure causes.

The Impact of Pistacia khinjuk plant gender on silver nanoparticle synthesis: Are extracts of root obtained from female plants preferentially used?

Pistacia khinjuk, a dioecious plant native to Southeast Anatolia, Turkey, features distinct male and female individuals with varying bioactive compound profiles. This study investigates the gender-specific phytochemical composition of root extracts from male and female Pistacia khinjuk plants and their influence on the green synthesis of silver nanoparticles. Using natural bioactive compounds such as polyphenols, flavonoids, alkaloids, and terpenoids as reducing and stabilizing agents, the study demonstrates significant differences between the nanoparticles synthesized from male and female root extracts.

Antimicrobial resistance and epidemiological patterns of Streptococcus pyogenes in Türkiye.

Background: Drug-resistant Group A beta-hemolytic streptococci remain significant infectious agents globally. This study investigated the major S. pyogenes strains responsible for infections in Türkiye and their susceptibility to beta-lactam and macrolide antibiotics.

Isolation and probiotic evaluation of Apilactobacillus kunkeei and Bombella sp. from Apis mellifera anatoliaca and Bombus terrestris.

The Anatolian honey bee (Apis mellifera anatoliaca) and Bombus terrestris are important species in Türkiye. In this context, protecting the health of these honey bees is particularly important. Lactic acid bacteria (LAB) and acetic acid bacteria (AAB) are very important for the health of bees.

Upshot of Some Bioactive Compounds on Angiogenesis in Retinal Pigment Epithelial Cells.

Nowadays, the use of monoclonal antibodies to target angiogenic signalling pathways is common, but, unfortunately, the clinical activity of these agents is limited. Thus, the development of approaches targeting multiple pathways for anti-angiogenic effect will lead to increase the clinical benefit. For this purpose, oleuropein, hesperidin, piperine, proanthocyanidins and retinoic acid, which have previously been proven to be bioactive components, anti-angiogenic performances were experimentally tested in retinal pigment epithelial cells.

Impacts of microplastic accumulation in aquatic environment: Physiological, eco-toxicological, immunological, and neurotoxic effects.

The presence of microplastics (MPs) in aquatic ecosystem has become a pressing global concern. MPs pose a significant threat to aquatic ecosystems, with devastating consequences for both aquatic life and human health. Notably, freshwater ecosystems are particularly vulnerable to MPs pollution.

Lower Urinary Tract Symptoms and Fall Risk: An Important Problem in Older Women with Cognitive Frailty.

Introduction And Hypothesis: The objective of our study is to investigate the presence of lower urinary tract symptoms (LUTS) and its correlation with the risk of falling in older women with cognitive frailty.

Methods: The descriptive study was conducted on 102 female older adults, 60 women were classed as cognitively frail and 42 as healthy. Women were classified as having mild cognitive impairment based on the Clinical Dementia Rating Scale and as frail based on the Clinical Frailty Scale.

Cryptosporidiosis as an opportunistic infection in colorectal cancer patients.

Cryptosporidium spp. is an opportunistic protozoan parasite that primarily affects immunocompromised individuals, including those with colorectal cancer (CRC). This study investigates the prevalence and clinical significance of Cryptosporidium spp.

Design and Development of a Self-Report Competence Scale for The Assessment of Prehospital Health Professionals' Competence in Response to Radiological Events.

Objectives: The objective of this study was to develop a self-report scale for the assessment of the competence of pre-hospital health professionals in responding to radiological incidents.

Methods: Based on the findings of a systematic review analyzing the literature, the instrument followed the processes of item generation, expert opinion, language control, pilot study, and field testing.

Results: In the exploratory factor analysis, 48 items were excluded on the grounds of insufficient common variance (>0.

Examination of immunohistochemical of the effects of flattened and unflattened radiotherapy beams in nude mice breast cancer xenografts.

Purpose: The aim of this study was to investigate the radiobiological effects underlying the inhibition of breast cancer (BCa) following radiotherapy in nude mice models, and to evaluate the impact of changes in immunohistochemical parameters induced by FF and FFF beams.

Materials And Methods: The study included thirty-six adult nude mouse models, which were randomly assigned to five groups: control (G1), breast cancer (BCa) (G2), FF-400 MU/min (G3), FFF-1100 MU/min (G4), and FFF-1800 MU/min (G5). The control group received neither radiation nor treatment, while the BCa group had a cancer model without radiation.

[Measles, Rubella, Mumps and Varicella Seropositivity in Health Technician Students: A Seroprevalence Study].

Measles, rubella, mumps and chickenpox infections are among the childhood diseases that can be prevented by vaccination. Healthcare workers are at greater risk of diseases transmitted through contact with patients' respiratory secretions, infected blood and body fluids. Students studying in the field of health are at the risk of encountering infectious diseases as much as healthcare personnel during their internship and practice experience in healthcare institutions during their education.

Investigation of the antibacterial activity of L. and its anti-QS potential on PAO1.

The study aims to evaluate the Quorum Sensing (QS) system inhibition against some Gram-positive and Gram-negative bacteria detected by molecular modeling of R. cathartica L. plant extract.

The psychometric properties of the Four Square Step Test in older adults with mild cognitive impairment.

Purpose: The study aimed to determine the test-retest, interrater, and minimum detectable change, concurrent and known-groups validity in older adults with mild cognitive impairment. Minimal detectable change values are the degree of change needed to exceed a measurement's error within a confidence limit.

Methods: A total of 46 older adults with mild cognitive impairment and 34 healthy controls were included.

Greener Synthesis of Poly(LIM--DVB--AMPS): A Sustainable Approach to Methylene Blue Removal.

A novel environmentally friendly adsorbent, poly(limonene--divinylbenzene--2-acrylamido-2-methyl-1-propanesulfonic acid, LIM--DVB--AMPS), was synthesized and applied for the adsorption of methylene blue from aqueous solutions in this study. The structure, morphology, and thermal stability of the green adsorbent were determined by the FTIR, SEM, TGA/DTA/DTG, and BET techniques, ζ potential, and elemental analysis. The efficiency of the adsorption process was improved with respect to several experimental conditions, viz.

EEG channel and feature investigation in binary and multiple motor imagery task predictions.

Introduction: Motor Imagery (MI) Electroencephalography (EEG) signals are non-stationary and dynamic physiological signals which have low signal-to-noise ratio. Hence, it is difficult to achieve high classification accuracy. Although various machine learning methods have already proven useful to that effect, the use of many features and ineffective EEG channels often leads to a complex structure of classifier algorithms.