Retinal Vascular Complications in Cocaine Abuse: A Case Report and a Literature Review.

This comprehensive review examines the ocular vascular complications of cocaine use, focusing on its effects on retinal vasculature and inflammation. A rare case of bilateral frosted branch angiitis (FBA) in a 48-year-old man with a history of intranasal cocaine abuse is presented as an illustrative example to stimulate discussion. The case highlights severe retinal ischemia and vascular sheathing, with no identifiable infectious or autoimmune cause, ultimately complicated by systemic vascular events.

Urate Levels as a Predictor of the Prevalence and Level of Cardiovascular Risk Factors: An Identificación de La PoBlación Española de Riesgo Cardiovascular y Renal Study.

(1) Background: Urate levels lower than the classical cut-off point for defining hyperuricemia can increase cardiovascular risks. The aim of this study is to determine if there is a relationship between different urate levels and classic cardiovascular risk factors (CVRFs). (2) Methods: A cross-sectional study of the inclusion visits of the patients recruited to the IBERICAN study was conducted.

Biomechanical coordination and variability alters following repetitive movement fatigue in overhead athletes with painful shoulder.

Most sports and leisure activities involve repetitive movements in the upper limb, which are typically linked to pain and discomfort in the neck and shoulder area. Movement variability is generally expressed by changes in movement parameters from one movement to another and is a time-dependent feature of repetitive activities. The purpose of this study was to examine the effect of repeated movement-induced fatigue on biomechanical coordination and variability in athletes with and without chronic shoulder pain (CSP).

The influence of resistance training on inflammatory markers, body composition and functional capacity in healthy older adults: A systematic review and meta-analysis.

Background: Older adults experience chronic inflammation, which is associated with health conditions such as sarcopenia, and resulting in reduced functional capacity. Resistance training (RT) is a beneficial intervention for improving health in the elderly.

Objective: This study aimed to investigate the effect of RT on inflammatory biomarkers, body composition, and functional capacity in healthy adults aged 60 years and over.

Vasorelaxant effect of fennel seeds (Foeniculum vulgare Mill) extracts on rat mesenteric arteries: Assessment of phytochemical profiling and antioxidant potential.

Ethnopharmacological Relevance: Hypertension is a serious health problems and a leading cause of adult mortality worldwide. Foeniculum. vulgare Mill, a plant traditionally used for various ailments, including cardiovascular disorders such as hypertension.

The increasing role of the allergist in the management of infusion reactions at the Oncology Infusion Center.

Background: Hypersensitivity reactions to chemotherapy disrupt treatment schedules and compromise patient outcomes. Rapid Drug Desensitization (RDD) enables patients to tolerate future treatments after an allergy workup. However, Same-Day Desensitization (SDD) is a novel approach that capitalizes on RDD to allow the continuation of chemotherapy on the same day as the index reaction, preventing treatment delays.

Open-source LLMs for text annotation: a practical guide for model setting and fine-tuning.

Unlabelled: This paper studies the performance of open-source Large Language Models (LLMs) in text classification tasks typical for political science research. By examining tasks like stance, topic, and relevance classification, we aim to guide scholars in making informed decisions about their use of LLMs for text analysis and to establish a baseline performance benchmark that demonstrates the models' effectiveness. Specifically, we conduct an assessment of both zero-shot and fine-tuned LLMs across a range of text annotation tasks using news articles and tweets datasets.

A brief package of tele-sexual counseling based on Islamic emotion-focused therapy versus tele-sexual health education on sexual intimacy in pregnant women: A randomized clinical trial.

Background: Physical and emotional changes in pregnancy may reduce sexual intimacy. Pregnant women need empowerment through short-term cultural-based interventions regarding sexual intimacy for better expression of sexual beliefs and expectations. Since studies are limited regarding Islamic emotion-focused therapy (IEFT), this study was conducted to compare the effect of tele-sexual counseling (IEFT) versus tele-sexual health education on sexual intimacy in pregnant women.

A Nine-Year-Old Girl With Cornelia de Lange Syndrome: A Case Report and Review of the Literature.

Cornelia de Lange syndrome is a genetic disorder that affects multiple systems. It is characterized by growth delays and psychomotor retardation associated with various anomalies, including hirsutism, facial dysmorphism, cardiac abnormalities, upper-extremity malformations, and gastrointestinal disorders. Early detection and appropriate management of associated disorders are essential for achieving favorable outcomes.

Is there a correlation among landing stability, ankle dorsiflexion range of motion, and ankle stiffness during single-leg landing?

Background: Even though both landing stability and ankle dorsiflexion stiffness (ankle DR-stiffness) have been independently identified as risk factors associated with non-contact injuries, no study has specifically investigated the relationship between these two variables.

Methods: Twenty male recreational athletes volunteered to participate in this study. Their ankle DF-ROM based on the weight-bearing lunge test, and landing stability based on the dynamic postural stability index (DPSI) and time to stabilization (TTS) were evaluated during a single-leg landing (SLL).

A rare case of soft tissue chondroblastoma of the quadratus femoris muscle: A case report and literature review.

Chondroblastomas are very rare benign primary bone tumors that typically develop in bones in young adults. Extraosseous chondroblastomas are extremely rare, with a few case reports documented in the literature. The treatment is surgical with a high healing rate.

Catch-Up Saccades in Vestibulo-Ocular Reflex Deficit: Contribution of Visual Information?

Objectives: Catch-up saccades help to compensate for loss of gaze stabilization during rapid head rotation in case of vestibular deficit. While overt saccades observed after head rotation are obviously visually guided, some of these catch-up saccades occur with shorter latency while the head is still moving, anticipating the needed final eye position. These covert saccades seem to be generated based on the integration of multisensory inputs.

Mycotic aortic aneurysm secondary to spondylodiscitis: A case report and review.

Mycotic aneurysms are a rare but potentially life-threatening complication of infections, particularly those involving the spine. Spondylodiscitis, a bacterial or fungal infection of the intervertebral disc, is a known risk factor for the development of mycotic aneurysms. Early diagnosis and prompt treatment are crucial for improving patient outcomes.

Lifestyle Habits and Nutritional Profile of the Spanish Population: A Comparison Between the Period During and After the COVID-19 Pandemic.

The aim of this study was to investigate the changes in habits regarding the health and lifestyle of the Spanish population during and after the COVID-19 pandemic. A cross-sectional design was used. Data were collected during the pandemic from 22,181 participants and after the pandemic from 3907 participants using the NutSo-HH Scale, assessing demographic, nutritional, and lifestyle variables.

Graph analysis of guilt processing network highlights links with subclinical anxiety and self-blame.

Maladaptive forms of guilt, such as excessive self-blame, are common characteristics of anxiety and depressive disorders. The underlying network consists of multiple associative areas, including the superior anterior temporal lobe (sATL), underlying the conceptual representations of social meaning, and fronto-subcortical areas involved in the affective dimension of guilt. Nevertheless, despite understanding the circuitry's anatomy, network-level changes related to subclinical anxiety and self-blaming behaviour have not been depicted.

Rheumatoid Purpura in Children: A Retrospective Study.

Introduction Rheumatoid purpura, also referred to as Schönlein-Henoch disease, is a form of systemic vasculitis that is characterized by the presence of IgA deposits within the walls of small vessels. The primary symptoms include skin purpura, arthralgia, abdominal discomfort, and urinary tract abnormalities. While often benign, the disease can result in severe complications, particularly those affecting the digestive and renal systems, which require urgent medical attention.

Secretory Breast Carcinoma: A Rare Breast Cancer With an Excellent Behavior.

Secretory breast carcinoma (SBC) is a rare breast cancer subtype, histologically, defined by abundant eosinophilic secretions with a triple-negative staining on immunohistochemistry. The diagnosis is made histologically and often requires complementary methods such as immunohistochemical studies and fluorescence in situ hybridization (FISH). Surgery, whether conservative or radical, is the preferred treatment.

Prevalence of obesity in primary care patients: The IBERICAN study.

Background And Aims: Obesity has an important role in the prognosis of the patients, and important regional differences were described in Spain. The aim is to determine the prevalence of obesity in Spanish primary care patients and its geographical distribution.

Methods And Results: Prevalence study that included patients from the baseline interview of the IBERICAN study.

Evaluation of leg symmetry in muscle oxygen saturation during submaximal to maximal cycling exercise.

It is unclear whether physiological responses, such as muscle oxygen saturation (SmO), can be considered symmetrical during cycling. This knowledge has important practical implications for both training and performance assessment. The aim of this study was to determine whether oxygenation profiles in the three active muscles of both legs were symmetrical during cycling at different intensities.

[Combination drug therapy in pulmonary hypertension: switch from selexipaq to intravenous trepostinil].

A wide range of substances is currently available for the treatment of patients with pulmonary arterial hypertension. The current recommendations for initial drug therapy are based on the patient's risk profile. For patients at high risk, an initial triple combination therapy with different substances including prostanoids is recommended.