5 results match your criteria: "Yangzhou second people's Hospital[Affiliation]"
C-di-GMP@ZIF-8 nanocomposite injectable hydrogel based on modified chitosan and hyaluronic acid for infected wound healing by activating STING signaling.
Int J Biol Macromol
September 2024
Yangzhou Second People's Hospital (North District Hospital of Northern Jiangsu People's Hospital) Affiliated to Nanjing University, Yangzhou 225007, Jiangsu, China. Electronic address:
The treatment of infected wounds relies on antibiotics; however, increasing drug resistance has made therapeutic processes more difficult. Activating self-innate immune abilities may provide a promising alternative to treat wounds with bacterial infections. In this work, we constructed an immunogenic injectable hydrogel crosslinked by the Schiff base reaction of carboxymethyl chitosan (NOCC) and aldehyde hyaluronic acid (AHA) and encapsulated with stimulator of interferon genes (STING) agonist c-di-GMP loaded ZIF-8 nanoparticles (c-di-GMP@ZIF-8).
View Article and Find Full Text PDFIdentification of a lactylation-related gene signature to characterize subtypes of hepatocellular carcinoma using bulk sequencing data.
J Gastrointest Oncol
August 2024
Department of Oncology, Yangzhou Hongquan Hospital, Yangzhou, China.
Background: Prior studies indicate that lactylation regulates various biological mechanisms within cancer. However, lactylation-related genes (LRGs) have been found to have limited value in predicting the prognosis of hepatocellular carcinoma (HCC). The aim of this study was to review HCC LRGs using data from The Cancer Genome Atlas (TCGA).
View Article and Find Full Text PDFKnowledge graph construction for heart failure using large language models with prompt engineering.
Front Comput Neurosci
July 2024
Department of Cardiovascular, Northern Jiangsu Province People Hospital of Yangzhou University, Yangzhou, Jiangsu, China.
Article Synopsis
- Constructing a knowledge graph for diseases, specifically heart failure, is important for enhancing clinical diagnosis, treatment, and health management, but current methods often struggle with limited training data and out-of-distribution entities.* -
- This study introduces an innovative pipeline that uses large language models, prompt engineering, and expert refinement to improve the design and extraction phases of knowledge graph construction.* -
- Results show the proposed TwoStepChat method significantly outperforms traditional methods, saving 65% of annotation time and effectively handling information not present in training data.*
Effect of the theory of planned behavior on primipara breastfeeding.
Ann Palliat Med
April 2021
Department of Gynaecology, Yangzhou Second People's Hospital, Yangzhou, China.
Background: Breastfeeding is the most effective way to provide food for the healthy growth and development of babies. It has been reported in the literature that interventions on parturients, with the theory of planned behavior (TPB) as the guiding framework, can achieve good results. The purpose of the present study was to explore the effect of the TPB on primipara breastfeeding.
View Article and Find Full Text PDF[A prospective controlled study of psychosomatic and immunologic change in recently bereaved people].
Zhonghua Shen Jing Jing Shen Ke Za Zhi
April 1991
Yangzhou second people's Hospital, Jiangsu.
This research was carried out in 45 bereaved people who were the close relatives of a bus accident victims. Their mental and physical conditions, IgA, IgG, IgM, C3 and C4 levels were measured. It reveals that mental and physical conditions of the investigated group declined and the incidence of infectious diseases increased in comparison with the control group.
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