Long noncoding RNA enhances the malignant phenotype of bladder cancer by acting as a competing endogenous RNA on microRNA-496 thereby increasing HMGB1 expression.

The long noncoding RNA nicotinamide nucleotide transhydrogenase antisense RNA 1 () is a key malignancy regulator in a variety of human cancers. In this study, we first measured the expression of in bladder cancer and examined its role in cancer progression. The mechanisms behind the oncogenic functions of in bladder cancer were explored.