34 results match your criteria: "Yamashita Hospital[Affiliation]"

Article Synopsis
  • The TOKYO criteria, initially proposed for standardized reporting of endoscopic transpapillary biliary drainage outcomes, face limitations in newer techniques like endoscopic ultrasound and device-assisted endoscopy.
  • A new committee is updating these criteria to better reflect current clinical practices in managing various biliary conditions, recognizing the need for comprehensive outcome evaluations beyond just stent patency.
  • The revised TOKYO criteria 2024 aim to enhance the design and reporting of clinical studies by introducing a "stent-demanding time" concept for a more thorough assessment of endoscopic biliary drainage outcomes.
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Article Synopsis
  • The study aimed to predict the success of nonsurgical treatment, specifically extracorporeal shock wave lithotripsy (ESWL), for removing pancreatic stones in patients and to find the optimal number of treatment sessions needed.
  • Data from 164 patients treated between 1992 and 2020 indicated that 79% achieved total stone clearance, with an average of 3 ESWL sessions, and an optimal threshold of 7 sessions was identified for effective treatment.
  • Results showed that patients who underwent 7 or fewer sessions had a higher clearance rate (87%) compared to those with more sessions (48%), leading to the recommendation to consider other medical or surgical options if stones remain after 7 sessions.
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Objectives: We aimed to determine when a coexisting pseudocyst was likely to complicate the nonsurgical treatment of pancreatolithiasis.

Methods: We treated 165 patients with pancreatolithiasis nonsurgically between 1992 and 2020, including 21 with pseudocysts. Twelve patients had a single pseudocyst less than 60 mm in diameter.

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Article Synopsis
  • * Imaging suggested primary sclerosing cholangitis, and while steroid therapy improved some symptoms, a bile duct biopsy indicated a possible adenocarcinoma leading to surgery.
  • * After surgery complications arose, leading to the need for additional surgery, and prednisolone was reintroduced to manage recurring symptoms and increased eosinophil infiltration was observed in the tissue samples.
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Objectives: Optimal management of type 1 gastric neuroendocrine tumors (T1-GNETs) remains unknown, with few reports on their long-term prognosis. This study investigated the clinical characteristics and long-term prognosis of T1-GNETs.

Methods: We reviewed the medical records of patients diagnosed with T1-GNET during 1991-2019 at 40 institutions in Japan.

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Background: Many guidelines for nonsurgical treatment of pancreatolithiasis suggest little guidance for patients with pancreatolithiasis who do not have abdominal pain. Some patients with pancreatolithiasis whom we have treated nonsurgically with extracorporeal shock-wave lithotripsy did not have abdominal pain, and we describe one of them here.

Methods And Results: A 42-year-old man complaining of an 8-kg weight loss over 6 months was admitted to a nearby hospital, where fasting blood sugar and hemoglobin A1c values were 500 mg/dL and 11.

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Weight loss improves the liver pathophysiological status of nonalcoholic fatty liver disease (NAFLD) patients. However, there are few studies that investigate the accurate relationships between nutritional intake and disease progression in NAFLD patients. A total of 37 biopsy-confirmed NAFLD patients were enrolled in this study.

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Objectives: Endoscopists often suffer from musculoskeletal disorders due to posture-specific workloads imposed by precise maneuvering or long procedural duration. An ergonomic motion tracking system for endoscopy suite (EMTES) was developed using Azure Kinect sensors to evaluate the occlusion, accuracy, and precision, focusing mainly on upper and lower limb movements.

Methods: Three healthy male participants pointed the prescribed points for 5 s on the designated work envelopes and their coordinates were measured.

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Objective: Clinical guidelines consider abdominal pain an indication for nonsurgical treatment of pancreatolithiasis. We examined benefit from nonsurgically treating asymptomatic pancreatolithiasis.

Methods: We retrospectively reviewed 165 patients with pancreatolithiasis who underwent nonsurgical treatment between 1992 and 2020.

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Objectives: While chronic pancreatitis associated with pancreatolithiasis presents with pain, exocrine and endocrine pancreatic functions worsen with time. We examined outcomes of nonsurgical treatment.

Methods: Between 1992 and 2020, we treated pancreatolithiasis nonsurgically in 165 patients with chronic pancreatitis using extracorporeal shock wave lithotripsy alone or followed by endoscopic procedures.

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Article Synopsis
  • Due to new insights and updates to the Japanese autoimmune pancreatitis (AIP) diagnostic criteria in 2018, the existing 2013 consensus guidelines needed revision.
  • A group of 20 AIP specialists analyzed 5218 articles from 1963 to 2019 to extract clinical statements and developed 39 clinical questions and statements across various aspects of AIP.
  • A modified Delphi method was used to validate these statements, and with moderator evaluation, the revised Japanese consensus guidelines for AIP were proposed in 2020.
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There has been little evidence assessing the prevalence of musculoskeletal disorders (MSDs) among endoscopists performing recent diagnostic and therapeutic endoscopic procedures requiring prolonged procedural times. We evaluated the prevalence and identified the risk factors for developing MSDs, focusing on procedural time. An electronic survey of endoscopists (n = 213) employed at the Nagoya University Hospital and its affiliated hospitals was developed by a multidisciplinary group.

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Background: The closure of mucosal defects after colorectal endoscopic submucosal dissection (ESD) remains difficult. Therefore, various methods and devices have been developed to aid in this procedure. However, a standard method for mucosal defect closure after ESD has not been established.

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Background: The feasibility of magnetic anchor-guided endoscopic submucosal dissection (MAG-ESD) using a neodymium magnet for colorectal tumors has not been evaluated. The aim of this study was to clarify the feasibility of MAG-ESD for colorectal tumors.

Methods: This prospective trial was conducted at Yamashita Hospital.

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Background: The incidence of mixed hepatitis C virus (HCV) genotype infection is variable, and a few reports exist regarding the efficacy of direct-acting antivirals (DAA) therapy for mixed genotype. We aimed to investigate the prevalence of mixed genotype and its impact on the virologic response to DAA therapy.

Methods: A total of 365 patients with chronic HCV infection who completed antiviral therapy were recruited.

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Article Synopsis
  • The study aimed to assess the effectiveness and safety of administering S-1 chemotherapy on alternate days as a second-line treatment for patients with unresectable pancreatic cancer.
  • A total of 77 patients were involved, with similar median overall survival between those taking S-1 daily (4.5 months) and those taking it every other day (4.4 months), and low response rates in both groups.
  • While alternate-day treatment showed a lower incidence of severe side effects (25.6% vs. 47.2% for daily treatment), it ultimately did not prove to be noninferior in effectiveness to daily dosing.
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The optimal term of follow-up for patients who achieve sustained virological responses (SVR) is an important topic because of the widespread use of direct-acting antivirals (DAA), which achieve a high SVR rate. Investigations of long-term follow-up among patients with SVR after interferon (IFN) therapy have reported that approximately 80%-100% of patients maintained SVR. However, the long-term durability of SVR to DAA treatment is unknown.

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Background And Aims: The feasibility of magnetic anchor-guided endoscopic submucosal dissection (MAG-ESD) using a neodymium magnet for gastric lesions has not been clarified. The aim of study was to evaluate the feasibility of MAG-ESD using neodymium magnets while treating gastric lesions.

Methods: This prospective trial was conducted at the Yamashita Hospital.

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