29 results match your criteria: "Yale School of Medicine and Yale-New Haven Health[Affiliation]"

Most patients with end-stage kidney disease value their health-related quality of life (HRQoL) and want to know how it will be affected by their dialysis modality. We extended the findings of two prior clinical trial reports to estimate the effects of frequent compared to conventional hemodialysis on additional measures of HRQoL. The Daily Trial randomly assigned 245 patients to receive frequent (six times per week) or conventional (three times per week) in-center hemodialysis.

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Article Synopsis
  • End-stage renal disease (ESRD) leads to high circulating levels of prolactin, but its connection to health outcomes and the impact of hemodialysis frequency on prolactin levels is not well understood.
  • The FHN Trials investigated the effects of different hemodialysis frequencies on health-related quality of life and measured serum prolactin levels in a large patient cohort over one year.
  • Results indicated that while many ESRD patients had elevated prolactin levels, these levels did not correlate with age or health measures, and increased hemodialysis frequency did not lower serum prolactin concentrations.
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Management of older people on dialysis requires focus on the wider aspects of aging as well as dialysis. Almost all frail and older patients receiving dialysis will default to in-center hemodialysis, although the availability of assisted peritoneal dialysis enables dialysis at home. As with any disease management decision, patients approaching end-stage renal disease need all the appropriate facts about their prognosis, the natural history of their disease without dialysis, and the resulting outcomes and complications of the different dialysis modalities.

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Objectives: Racial/ethnic disparities in healthcare, including orthopedics, have been extensively documented. However, the level of knowledge among orthopedic surgeons regarding racial/ethnic disparities is unknown. The purpose of this study is to determine the views of orthopedic surgeons on (1) the extent of racial/ethnic disparities in orthopedic care, (2) patient and system factors that may contribute, and (3) the potential role of orthopedic surgeons in the reduction of disparities.

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