Hypoxia Regulates Brown Adipocyte Differentiation and Stimulates miR-210 by HIF-1α.

MicroRNAs (miRNAs) are short sequences of single-stranded non-coding RNAs that target messenger RNAs, leading to their repression or decay. Interestingly, miRNAs play a role in the cellular response to low oxygen levels, known as hypoxia, which is associated with reactive oxygen species and oxidative stress. However, the physiological implications of hypoxia-induced miRNAs ("hypoxamiRs") remain largely unclear.

Evaluation of as a Feed Additive in Low-Protein Diets of Broilers.

is a natural antioxidant product that has the ability to improve the performance of poultry. Therefore, the present study aimed to evaluate the effect of using as a feed additive in broiler diets. A total of 252 daily male Ross 308 chicks were randomly assigned to six groups.

Changes in the Phenotype and Metabolism of Peritoneal Macrophages in Mucin-2 Knockout Mice and Partial Restoration of Their Functions In Vitro After L-Fucose Treatment.

In the development of inflammatory bowel disease (IBD), peritoneal macrophages contribute to the resident intestinal macrophage pool. Previous studies have demonstrated that oral administration of L-fucose exerts an immunomodulatory effect and repolarizes the peritoneal macrophages in vivo in mice. In this study, we analyzed the phenotype and metabolic profile of the peritoneal macrophages from mice, as well as the effect of L-fucose on the metabolic and morphological characteristics of these macrophages in vitro.

Electrolytic Ni-P and Ni-P-Cu Coatings on PCM-Loaded Expanded Graphite for Enhanced Battery Thermal Management with Mechanical Properties.

This study addresses the thermal management challenge in battery systems by enhancing phase change material composites with Ni-P and Ni-P-Cu coatings on phase change material/expanded graphite structures. Traditional phase change materials are limited by low thermal conductivity and mechanical stability, which restricts their effectiveness in high-demand applications. Unlike previous studies, this work integrates Ni-P and Ni-P-Cu coatings to significantly improve both the thermal conductivity and mechanical strength of phase change material/expanded graphite composites, filling a crucial gap in battery thermal management solutions.

Creep Resistance and Microstructure Evolution in P23/P91 Welds.

This paper summarizes the results of investigations into heterogeneous P23/P91 welds after long-term creep exposure at temperatures of 500, 550 and 600 °C. Two variants of welds were studied: In Weld A, the filler material corresponded to P91 steel, while in Weld B, the chemical composition of the consumable material matched P23 steel. The creep rupture strength values of Weld A exceeded those of Weld B at all testing temperatures.

Detailed Analysis of the Debris-Fretting Damage Areas on Coated Fuel Cladding.

Fuel failure caused by fretting damage to cladding remains a relevant issue despite decades of research and development aimed at enhancing the physical parameters of fuel. This paper presents the results of experiments conducted at the Research Centre Řež on Zr-1%Nb alloy tube specimens covered with protective coatings made of chromium (Cr) and nitrogen (N) compounds. The experiments involved debris-fretting tests under dry conditions at room temperature as well as microscopic measurements of groove depths.

Properties, Advantages, and Prospects of Using Cobalt-Free Composites Based on Tungsten Carbide in Industry.

This paper reviews recent advances in the synthesis of cobalt-free high-strength tungsten carbide (WC) composites as sustainable alternatives to conventional WC-Co composites. Due to the high cost of cobalt, limited supply, and environmental concerns, researchers are exploring nickel, iron, ceramic binders, and nanocomposites to obtain similar or superior mechanical properties. Various synthesis methods such as powder metallurgy, encapsulation, 3D printing, and spark plasma sintering (SPS) are discussed, with SPS standing out for its effectiveness in densifying and preventing WC grain growth.

Full-Locked Coil Ropes with HDPE Sheath: Studies of Mechanical Behavior of HDPE Under Accelerated Aging.

In accordance with German guideline ZTV-ING Part 4, full-locked coil ropes are provided with a three-layer corrosion protection coating based on epoxy resin and polyurethane, which must be renewed regularly. An alternative method is to use a coating of high-density polyethylene (HDPE), which is extruded onto the rope. In this article, the mechanical behavior of the thermoplastic material is studied, taking into account various accelerated aging processes, which are derived from the climatic boundary conditions of a real bridge structure and implemented in tests.

Analysis of the Influence of Manufacturing Technology on Selected Static, Fatigue and Morphological Properties of CFRP Composites.

The aim of this study was to compare the mechanical properties of carbon-fiber-reinforced polymer (CFRP) composites produced using three popular technologies. The tests were performed on composites produced from prepregs in an autoclave, the next variant is composites produced using the infusion method, and the third variant concerns composites produced using the vacuum-assisted hand lay-up method. For each variant, flat plates with dimensions of 1000 mm × 1000 mm were produced while maintaining similar material properties and fabric arrangement configuration.

Analysis of Tool Wear in Finish Turning of Titanium Alloy Ti-6Al-4V Under Minimum Quantity Lubrication Conditions Observed with Recurrence Quantification Analysis.

Titanium alloys, particularly Ti-6Al-4V, are widely used in many industries due to their high strength, low density, and corrosion resistance. However, machining these materials is challenging due to high strength at elevated temperatures, low thermal conductivity, and high chemical reactivity. This study investigates Recurrence Plot (RP) and Recurrence Quantification Analysis (RQA) to analyze tool wear during the finish turning of Ti-6Al-4V.

The Effect of the Addition of Silicon Dioxide Particles on the Tribological Performance of Vegetable Oils in HCT600X+Z/145Cr46 Steel Contacts in the Deep-Drawing Process.

Friction is an unfavourable phenomenon in deep-drawing forming processes because it hinders the deformation processes and causes deterioration of the surface quality of drawpieces. One way to reduce the unfavourable effect of friction in deep-drawing processes is to use lubricants with the addition of hard particles. For this reason, this article presents the results of friction tests of dual-phase HCT600X+Z steel sheets using the flat die strip drawing test.

Evaluation of the Microstructure and Properties of As-Cast Magnesium Alloys with 9% Al and 9% Zn Additions.

The need to reduce energy consumption means that it is necessary to reduce the weight of vehicles. However, a thick wall of massive elements promotes the formation of casting defects, which must be removed by either plastic processing (straightening) or welding methods (surface and internal discontinuities). Basic alloys contain Al and Zn as the main alloying elements.

Enhanced Tribological and Mechanical Properties of Copper-Modified Basalt-Reinforced Epoxy Composites.

The increasing demand for high-performance materials in industrial applications highlights the need for composites with enhanced mechanical and tribological properties. Basalt fiber-reinforced polymers (BFRP) are promising materials due to their superior strength-to-weight ratio and environmental benefits, yet their wear resistance and tensile performance often require further optimization. This study examines how adding copper (Cu) powder to epoxy resin influences the mechanical and tribological properties of BFRP composites.

Shear Capacity of Hollow High-Performance Concrete Beams with Cross-Wound Carbon Fiber-Reinforced Polymer Reinforcement.

This paper introduces cross-wound CFRP shear reinforcement of hollow HPC beams. The CFRP reinforcement was manufactured in the form of a square tubular mesh from carbon rovings oriented at ±45° from the longitudinal axis. The shear reinforcement was made in two variants from carbon yarns with linear densities of 1600 and 3700 tex.

Advances in Electrically and Thermally Conductive Functional Nanocomposites Based on Carbon Nanotubes.

The paper presents a review of CNTs synthesis methods and their application as a functional filler to obtain polymer composites for various technical purposes for strain gauges, electrical heating, anti-static coatings, electrically conductive compounds, etc. Various synthesis methods allow CNTs with different morphology and structural properties to be created, which expands the possibilities of the application of such nanoscale structures. Polymers can provide such effects as 'shape memory' and self-repair of mechanical defects.

Influence of 3D Printing Conditions on Physical-Mechanical Properties of Polymer Materials.

The popularity of 3D printing technology is rapidly increasing worldwide. It can be applied to metals, ceramics, composites, hybrids, and polymers. Three-dimensional printing has the potential to replace conventional manufacturing technologies because it is cost effective and environmentally friendly.

Performance Restoration of Chemically Recycled Carbon Fibres Through Surface Modification with Sizing.

The recycling of Carbon Fibre-Reinforced Polymers (CFRPs) is becoming increasingly crucial due to the growing demand for sustainability in high-performance industries such as automotive and aerospace. This study investigates the impact of two chemical recycling techniques, chemically assisted solvolysis and plasma-enhanced solvolysis, on the morphology and properties of carbon fibres (CFs) recovered from end-of-life automotive parts. In addition, the effects of fibre sizing are explored to enhance the performance of the recycled carbon fibres (rCFs).

Multi-Parametric Optimization of 3D-Printed Components.

This study explores the experimental and theoretical optimization of process parameters to improve the quality of 3D-printed parts produced using the Fused Deposition Modeling technique. To ensure the cost-effective production of high-quality components, advancements in printing strategies are essential. This research identifies optimal 3D printing strategies to enhance the quality of finished products.

Impact of Cell Design Parameters on Mechanical Properties of 3D-Printed Cores for Carbon Epoxy Sandwich Composites.

The introduction of 3D printing technology has broadened manufacturing possibilities, allowing the production of complex cellular geometries, including auxetic and curved plane structures, beyond the standard honeycomb patterns in sandwich composite materials. In this study, the effects of cell design parameters, such as cell geometry (honeycomb and auxetic) and cell size (cell thickness and width), are examined on acrylonitrile butadiene styrene (ABS) core materials produced using fusion deposition modeling (FDM). They are produced as a result of the epoxy bonding of carbon epoxy prepreg composite materials to the surfaces of core materials.

Unveiling the Genetic Diversity and Demographic History of in Sierra Leone Using Genotyping-By-Sequencing.

is a rare Coffea species boasting a flavor profile comparable to Arabica coffee () and has a good adaptability to lowland tropical climates. This species faces increasing threats from climate change, deforestation, and habitat fragmentation in its West African homeland. Using 1037 novel SNP markers derived from Genotyping-by-Sequencing (GBS), we revealed the presence of three distinct natural populations (mean Fst = 0.

Physico-Chemical Properties of Granular Sorbents Based on Natural Bentonite Modified by Polyhydroxocations of Aluminum and Iron (III) by Co-Precipitation.

The physicochemical and adsorption properties of granular sorbents based on natural bentonite and modified sorbents based on it have been studied. It was found that modification of natural bentonite with iron (III) polyhydroxocations (mod. 1_Fe_5 GA) and aluminum (III) (mod.

Synthesis, Structure, and Electrophysical and Electrochemical Properties of Novel Composite LaMnO-LaFeO.

This article presents the synthesis, electrophysical, and catalytic properties of a LaMnO-LaFeO nanocomposite material. The nanocomposite was synthesized via the sol-gel (Pechini) method. X-ray diffraction (XRD) analysis revealed a polycrystalline, biphasic perovskite structure combining both hexagonal and cubic symmetry.

Heavy Metal Accumulation (Cd, As, Zn, Cu, Cr) in Hair and Bones of Small Mammal Prey of the Sentinel Species Common Genet () in an Anthropogenic Environment of Edough Mountain Forest, Northeastern Algeria.

Heavy metal pollution has complex impacts on terrestrial ecosystems, affecting biodiversity, trophic relationships, species health, and the quality of natural resources. This study aims to validate a non-invasive method for detecting heavy metals (Cd, As, Zn, Cu, Cr) in micromammalian prey, which constitute the primary diet of the common genet (), a mesocarnivore sensitive to habitat degradation. By focusing on prey remains (hair and bones) rather than entire fecal samples, this approach leverages the genet's selective feeding habits to assess the bioaccumulation of contaminants in its preferred prey.

Painful vision loss during air travel after vitrectomy with air tamponade: a case report.

Background: While the potentially hazardous effects of intraocular perfluorocarbon gases during air travel have been recognized, the equivalent risk of intraocular air tamponade is less known and has, to the best of our knowledge, not been reported yet.

Case Presentation: A 52-year-old white female experienced a complete loss of vision and pain in her left eye during air travel following pars plana vitrectomy with air tamponade. Clinical and multimodal imaging findings only a few hours after emergency landing indicated a transient central retinal artery occlusion due to a significant increase in intraocular pressure during the flight.

Astigmatism in Duane Retraction Syndrome.

Purpose: To compare the prevalence, magnitude, and type of astigmatism among patients with different Duane Retraction Syndrome (DRS) types.

Method: This retrospective cross-sectional study reviewed the records of 312 DRS patients. Patients were categorized into DRS Types 1, 2, 3, and bilateral cases.