1,725 results match your criteria: "Yüksek İhtisas Education Hospital[Affiliation]"

Background: No-reflow is a critical adverse event associated with percutaneous coronary intervention (PCI), particularly during saphenous vein graft (SVG) procedures. The Naples Prognostic Score (NPS) reflects inflammatory status, but its relationship with no-reflow remains unclear. Therefore, we aimed to evaluate the relationship between NPS and no-reflow occurrence following SVG PCI.

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Background: Mortality in patients after carotid artery stenting (CAS), a treatment approach for atherosclerotic carotid artery stenosis, is influenced by numerous factors. This study aimed to investigate the prognostic value of the Naples prognostic score (NPS), which reflects nutritional and inflammatory status, in CAS patients.

Methods: We retrospectively included 697 patients who underwent CAS from January 2016 to December 2020 at our institute.

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Background: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach was initially viewed as experimental and was reserved for highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, and in several centers, it is now offered as a standard of care option alongside surgical repair.

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Purpose: This study aimed to compare the effect of povidone iodine (PI) and chlorhexidine gluconate (CG) shower groups on the healing process in cesarean section operations.

Design: Randomized controlled trial.

Methods: Patients were recruited from Gynecology and Obstetrics Hospital in Turkey between February and May 2021.

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Coronary collateral flow (CCF) is crucial for myocardial viability in patients with obstructive coronary artery disease, specifically ST-elevation myocardial infarction (STEMI). However, hypertension can contribute to vascular dysfunction and hinder the formation of CCF. Wide pulse pressure (WPP), defined as ≥65 mmHg, may better reflect impaired cardiovascular health compared to classic blood pressure indices.

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: The prevalence of patent foramen ovale (PFO) has been found to be increased in patients with cryptogenic stroke, suggesting an association between these two clinical settings. Insulin resistance is a risk factor for the occurrence of stroke. The triglyceride glucose (TyG) index is a biomarker that reflects the IR status of the body.

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Article Synopsis
  • - The study aimed to assess how specific anatomical measurements from X-rays (volar tilt, radial length, radial inclination, and ulnar variance) can help predict deformities in patients with rheumatoid arthritis and diagnose the condition in those with nonspecific wrist pain.
  • - A total of 138 participants (98 with rheumatoid arthritis and 40 controls) were evaluated, revealing that those with rheumatoid arthritis had significantly lower volar tilt and radial length compared to the control group, but no differences were found between the rheumatoid arthritis groups with and without deformities.
  • - The findings suggest that low volar tilt and radial length may serve as early indications of rheumatoid arthritis on X-rays, potentially aiding in the diagnosis of hard-to-identify cases, especially
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Article Synopsis
  • AI technology in pathology relies on supervised machine learning and is increasingly used for tasks like detecting invasive breast cancer and analyzing tissue layers in colorectal specimens.
  • The study involved training convolutional neural networks (CNNs) using a large dataset of whole-slide images (WSIs) across different cancer types, achieving notable F1 scores for diagnostic accuracy.
  • After extensive training and external validation, the AI models demonstrated a high level of proficiency in identifying tumors and distinguishing between various tissue layers.
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Objective: Vascular endothelial growth factor is a signaling protein created by cells performing important bodily functions. Vascular endothelial growth factor is abundant in the lung, and plasma levels are elevated in patients with severe pulmonary arterial hypertension. An association between soluble urokinase plasminogen activator receptor, an inflammatory biomarker, and soluble urokinase plasminogen activator receptor levels and interstitial pulmonary and vascular involvement (e.

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Background: The Objective Structured Clinical Examination (OSCE) is a crucial assessment tool for evaluating learners' ability to apply theoretical knowledge in practical clinical situations. It is widely accepted by both students and educators, and the costs associated with conducting OSCE assessments vary depending on the field of study, how it is implemented, staffing needs, standardized patients, and duration of the examination. This study examines the expenses related to administering OSCEs in medical universities.

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Phantoms representing anatomical deformations are necessary to investigate and improve dynamic treatments. In this study, we aimed to produce a deformable liver phantom by simulating respiratory motion. The dynamically DEformable Liver Phantom (DELP) is designed to create a human-specific respiratory model and to produce synchronised, repeatable motion with this model.

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This study aimed long-term prognostic factors for percutaneous coronary intervention (PCI) in left main coronary artery (LMCA) disease, focusing on inflammatory parameters like Pan Immune-Inflammation Value (PIV) and Systemic Immune-Inflammation Index (SII). This retrospective, observational study involved 121 patients receiving unprotected LMCA PCI.The study's primary end point was MACE, including all-cause death, repeat revascularization and myocardial reinfarction.

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A case report with literature review: long-term follow-up of kidney autotransplantation in fibromuscular dysplasia.

J Nephrol

October 2024

Department of Internal Medicine, Division of Nephrology, Marmara University, School of Medicine, Pendik Research and Education Hospital, Fevzi Cakmak Mah. Mimar Sinan Cd. N:41, Pendik, 34854, Istanbul, Turkey.

Article Synopsis
  • * Treatment options include antihypertensive medication, surgical revascularization, and angioplasty, with kidney autotransplantation as an alternative for complex cases.
  • * A case study of a 22-year-old woman shows successful kidney autotransplantation led to improved kidney function and controlled blood pressure, highlighting it as a viable solution for severe cases of fibromuscular dysplasia.
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Background: We aimed to investigate effect of radiotherapy (RT) applications with different dose rates on cytogenetic damages, which focused on micronucleus (MN) formation, and evaluate how this damage varies by cisplatin in rats receiving head-neck RT.

Material And Methods: Thirty-six Sprague Dawley rats were divided into five groups. The first and second groups were irradiated at a dose rate of 300 monitor unit/minute (MU/min) and 600 MU/min, respectively.

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Background: Ralstonia pickettii is an aerobic Gram-negative non-fermentative bacillus. It is an opportunistic pathogen that has recently prompted nosocomial outbreaks. Although it has low virulence, it can cause a wide range of invasive diseases in immunosuppressive patients.

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  • The study investigates the effects of nanoencapsulated multi-strain probiotics on the health and performance of broiler chickens, specifically focusing on their ability to combat Salmonella Typhimurium.
  • A total of 2,800 Ross 308 chicks were divided into groups receiving different probiotic treatments, including standard and nanoencapsulated forms, before being challenged with Salmonella at 22 days old.
  • Results showed that birds fed the higher doses of nanoencapsulated probiotics (BLB-NPs II and III) had improved weight gain, enhanced immune response, lower Salmonella counts, and greater populations of beneficial gut bacteria compared to the control group.
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Article Synopsis
  • Congenital diarrhea can be tough to diagnose, especially when standard tests don't give clear results.
  • A female infant presented symptoms of osteopetrosis along with unexplained diarrhea, leading to genetic testing that uncovered a significant deletion on chromosome 16p13.3.
  • This case highlights the need to investigate genetic factors, like 16p13.3 deletions, when diagnosing conditions that seem to involve multiple symptoms.
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Background: Pericardial cysts, though rare and benign, can present with various clinical symptoms depending on their size and location in the body. The detection of these cysts typically relies on imaging studies for a conclusive diagnosis, with surgical removal being the definitive treatment.

Case Presentation: This case report details the clinical journey of a 32-year-old Iranian woman with a family history of breast and lung cancer, who experienced left-sided chest pain.

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This study aimed to identify the phenotypic features contributing to the development of left ventricular outflow tract obstruction (LVOTO) in patients with hypertrophic cardiomyopathy (HCM) and to evaluate the genotype‒phenotype relationship. This cross-sectional study included 96 patients diagnosed with HCM (mean age: 56.9 ± 13.

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Article Synopsis
  • * Data was collected from 16 centers, involving 142 patients, where 96.5% were stone-free 24 hours post-surgery, with a significant number achieving grade A (no fragments).
  • * The findings suggest that using FANS-UAS results in excellent safety and efficacy within 24 hours of surgery, with the only notable complication being transient fever in 7% of patients.
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Introduction: To investigate the presence of dysbiosis in patients with naive bladder cancer.

Methods: Twelve male patients with non-invasive bladder cancer and twelve age-matched healthy males had midstream urine and tissue samples taken. A history of endourological interventions was determined as an exclusion criterion, ensuring that the study was designed solely with naïve participants.

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Background: Unilateral chronic thromboembolism pulmonary disease (CTEPD) is very rare. There is limited information on the safety and efficacy of pulmonary endarterectomy (PEA) in this population. This study investigated the effectiveness of PEA in this unique disease.

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Purpose: This study aimed to compare the results of patients who underwent anterior component separation techniques (ACST) and those who did not undergo component separation techniques (non-CST) in complicated ventral hernia repairs (VHRs) and to investigate the effect of these techniques on quality of life (QoL).

Methods: A total of 105 patients who were operated for large ventral hernias were retrospectively analyzed. The patients were divided into the ACST group (n = 48) and the non-CST group (n = 57).

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The patient-reported outcomes for the new brand-generic teriflunomide in relapsing-remitting multiple sclerosis.

Clin Neurol Neurosurg

November 2024

Department of Neurology, Amiralam Hospital, Tehran University of Medical Sciences, Tehran, Iran,; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Unverstät zu Berlin, Experimental and Clinical Research Center, Berlin, Germany; Department of Regional Health Research and Molecular Medicine, University of Southern Denmark, Odense, Denmark. Electronic address:

Background: Patient-reported outcomes (PROs) provide valuable insights into the impact of disease-modifying therapies (DMTs) on patients' daily lives and disease progression. This study evaluates treatment satisfaction and tolerability among patients using a brand-generic Teriflunomide (Tebazio®, 14 mg tablet) manufactured by Zistdaru Danesh Biopharmaceuticals.

Materials And Methods: A Phase IV observational study was conducted on patients with Relapsing-Remitting Multiple Sclerosis (RRMS) who were either initiated on or switched to Teriflunomide 14 mg.

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